Associate Rare Disease Sales Representative

Position will cover a broad region along the US East Coast, across several multi-state territories.


About Krystal Bio: At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs.

Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient's end-to-end experience.

Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK®, for the treatment of Dystrophic Epidermolysis Bullosa (DEB), an ultra-rare disease. Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology.

Krystal is headquartered in Pittsburgh, PA, which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values.

Job Description Summary:

The Regional Gene Therapy Liaison (RGTL) will be a highly motivated, field-based professional who places a strong value on accountability, collaboration, and patient-centricity. This individual is a results-driven sales professional who utilizes their role to build trust with both internal and external stakeholders while executing against defined regional and territory objectives.

This role is an exceptional entry point into the ultra-rare disease and gene therapy space, offering meaningful territory ownership and the potential for long-term career growth.

The RGTL will support the promotion of Vyjuvek, a non-invasive, topical gene therapy for the treatment of patients with dystrophic epidermolysis bullosa (DEB). Vyjuvek is designed to treat DEB at the molecular level by delivering functional copies of the COL7A1 gene to enable production of COL7 protein and address the underlying disease-causing mechanism.

This role is highly field-intensive, requiring extensive travel (at least 75%), and will execute across multiple territories within a region with a focus on market development. The Regional Gene Therapy Liaison will contribute to the successful commercialization of Vyjuvek within their assigned region and will represent the "voice of the customer" to internal Krystal teams. They will bring energy and enthusiasm to the dermatology community and other specialties involved in the diagnosis, management, and treatment of DEB.

We are seeking a creative and adaptable sales professional, who values and excels in a collaborative team environment while also having strong capabilities in strategic thinking and time management. Krystal employees are expected to embrace diversity and work effectively with internal and external partners from a variety of backgrounds and experiences. The successful candidate must demonstrate integrity, professionalism, and strict adherence to corporate and industry compliance standards. Krystal offers a supportive, fast-paced, and industry-competitive environment.

The Regional Gene Therapy Liaison is a key member of Krystal's customer-facing field organization and partners with healthcare professionals to identify needs while compliantly educating stakeholders about Vyjuvek.

Employment Term:

This is an at-will, full-time, benefits-eligible position with an initial fixed term of six (6) months . Continued employment beyond the initial term, including extension or conversion to a full-time role, will be considered based on individual performance and business needs, but is not guaranteed.

Primary Responsibilities:

• Support achievement of sales objectives within the assigned region through effective promotion of Vyjuvek to pediatric dermatologists and other key stakeholders involved in the diagnosis, management, and treatment of DEB
• Execute territory strategies focused on market development, brand awareness, and patient identification through appropriate, HCP-driven initiatives
• Promote and educate healthcare professionals on the indication, usage, safety, and efficacy of Vyjuvek through in-person and virtual meetings, presentations, and educational interactions
• Effectively prioritize and manage time, travel, activities, and resources to optimize access to academic and community-based healthcare professionals
• Build and maintain consultative sales relationships and ensure consistent, professional communication with customers and prospects
• Collaborate cross-functionally with internal stakeholders and other commercial partners to support access and coordination at sites of care
• Utilize data, insights, and CRM tools to identify opportunities, prioritize accounts, and support informed territory execution
• Develop and implement a territory business plan aligned with regional goals and launch objectives
• Responsibly manage company resources, including in-office education (IOE) budgets, promotional materials, and patient-facing materials
• Foster teamwork and proactive communication to ensure alignment and coordination with peers across the field organization
• Demonstrate Krystal's corporate values through adherence to company policies, guidelines, and mission
• Maintain administrative requirements associated with territory management, including CRM documentation, expense reporting, business planning, and performance review
• Attend national, regional, and local meetings and conferences as assigned
• Perform other duties as assigned

Experience and Skills Desired:

• Strong patient-first mindset
• Bachelor's degree (BS/BA) required
• Minimum 5+ years of relevant sales experience, with at least 1+ year of pharmaceutical sales experience required
• Experience in specialty, hospital, or complex selling environments is a plus
• Exposure to complex reimbursement environments and multi-stakeholder selling models
• Demonstrated ability to build relationships, manage a territory, and consistently deliver strong performance against objectives
• Strong communication, facilitation, and presentation skills in both virtual and in-person settings
• Ability to work independently in a high-travel role (≥75% overnight and regional travel)
• Ability to collaborate effectively across cross-functional teams in a dynamic environment
• Must reside within or near the assigned territory
• Valid driver's license required

Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc. will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc.