Senior Principal Scientist, Cardiovascular, Translational Development

Position Summary Translational Development is part of the Global Research organization in BMS and leads late‑stage clinical, pharmacological, and translational research and development activities for the pipeline and supports the late‑stage portfolio for regulatory and life‑cycle management. Translational Development drives strategy across core therapeutic areas at BMS, including hematology, oncology, immunology, cardiovascular, and neuroscience. This group integrates laboratory science, clinical trial/biomarker, and asset development, as well as disease research, to maximize the potential of BMS’s current and future therapeutics. Incumbents with deep training and education in cardiovascular or related disease areas, including but not limited to neurocardiac research, are preferred. Key Responsibilities Designs and implements program‑specific development biomarker/translational plans. Responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement. Determines appropriate assays and vendors for clinical biomarkers and manages outsourcing of biomarker assay development and validation, partnering with Translational Sciences colleagues when applicable. Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs. Prepares and delivers internal and external translational/biomarker presentations. Maintains timelines for biomarker data‑related publication through interaction with Medical Communications and Publication team as needed. Keeps up‑to‑date on relevant scientific/technical literature to apply external knowledge to internal research programs and acts as a subject‑matter expert within the team to critically evaluate the literature regarding the asset and disease biology. Works with TM laboratory scientists and academic TLs to address nonclinical translational questions as needed. Participates or leads post‑hoc biomarker analysis and publication efforts. Supports regulatory submissions and regulatory interactions as needed. Participates in Diagnosis (PDx) biomarker assay development through collaboration with precision medicine group. Qualifications & Experience PhD with 5‑8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early‑ and/or late‑stage clinical programs in biotech or pharma. Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct, and completion. Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables. Demonstrated scientific and project leadership experience, including working in cross‑functional teams, mentoring, and managing projects, with the ability to identify risks and implement contingency plans. Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses. Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross‑functional issues across the organization. Ability to support multiple projects in a fast‑paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping. Compensation Overview Brisbane, CA – US: $184,060 – $223,036 Cambridge Crossing: $184,060 – $223,036 Princeton, NJ – US: $160,060 – $193,949 Benefits Health Coverage: Medical, pharmacy, dental, and vision care. Well‑being Support: Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Paid Time Off: US Exempt Employees: flexible time off (unlimited, with manager approval); Phoenix, AZ, Puerto Rico and Rayzebio exempt, non‑exempt, hourly employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays. Additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs, and an annual global shutdown between Christmas and New Year's Day. Bristol Myers Squibb is an equal‑opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law. #J-18808-Ljbffr