Scientist, Dissolution & Biopharmaceutical Modeling

At Lilly, Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre‑clinical phases through commercialization of drug substances and drug products. Our scientists and engineers develop key technical and business solutions across the portfolio using their deep technical expertise to accelerate testing of clinical hypothesis and overall drug development. Candidates should have hands‑on experience in analytical chemistry and/or pharmaceutical sciences, including exposure to techniques such as spectroscopy, chromatography, formulation development, or biopharmaceutics. They should be motivated to continue building their skills and deepen their understanding of molecular properties, product and process design, and product performance in order to support drug product development from early research through commercialization. Responsibilities Develop analytical methods and conduct experiments to aid early clinical formulation development to enable drug delivery of a broad range of synthetic drug molecules. Collaborate with formulation scientists to design experiments and guide selection and characterization of formulations for pre‑clinical and early clinical drug candidates. Partner with biopharmaceutical modeling scientists, analytical chemists, pharmaceutical scientists, and engineers to identify the appropriate drug form, formulation, and process characteristics that provide the desired drug product performance. Identify and mitigate technical risks for the performance and production of clinical and commercial drug products. Execute with attention to safety, quality, regulatory, GLP/GMP, and legal requirements for all activities. Author key regulatory documents, demonstrating appropriate understanding of product performance control strategy, and biopharmaceutics risk mitigation for clinical trials and product commercialization. Embrace diverse thought, background, and experience to deliver innovative solutions. Possess strong communication (oral, written), organizational, and leadership skills. Engage and influence the external scientific community to foster collaborations for innovation and to advance Lilly’s internal portfolio. Basic Requirements B.S. in Chemistry or Pharmaceutical Science, or other related discipline (e.g., material science). Understanding of analytical techniques and methods for characterizing physicochemical properties of drug molecules and performance of drug products (e.g., HPLC, UV, NIR, dissolution). Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F‑1 CPT, F‑1 OPT, F‑1 STEM OPT, J‑1, H‑1B, TN, O‑1, E‑3, H‑1B1, or L‑1. Additional Preferences Industry, research or internship experience relevant to the position is strongly preferred. Strong leadership, supervisor, teamwork, communication and writing skills. Knowledge of biopharmaceutics and pharmacokinetic principles, formulation development and pharmaceutical material sciences, and drug product factors impacting in vivo performance and manufacture. Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products. General understanding of techniques and instrumentation used in characterization of pharmaceutical drug products, especially dissolution and other product performance tests. Other Information Location: LTC‑N Campus in Indianapolis, IN. Travel: 0-10%. If you require accommodation, please complete the accommodation request form. EEO Statement Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Salary Range: $65,250 – $169,400. Full‑time employees also are eligible for a company bonus (depending, in part, on company and individual performance). Lilly offers a comprehensive benefit program that includes 401(k), pension; vacation; medical, dental, vision, prescription drug; flexible benefits; life insurance; leave benefits; well‑being benefits; etc. #J-18808-Ljbffr Initial Therapeutics, Inc.