Clinical Research Coordinator, Senior - Duke Cancer Institute

Position Overview The Oncology Clinical Research Unit (CRU) within the Duke Cancer Institute is seeking a Clinical Research Coordinator Sr. to support the Leukemia/MPN Clinical Research Team (CRT) within the Hematologic Malignancies & Cellular Therapy (HMCT) Clinical Research Program. In this role you will supervise a team of study coordinators and data managers/coordinators and lead day‑to‑day operations of multiple complex oncology clinical trials, including studies involving Investigational Products (IP). Responsibilities Lead study operations and coordination for multiple complex oncology clinical trials, including participant recruitment, screening, enrollment, and retention strategies; evaluate processes and implement solutions to improve study performance. Oversee study and site management activities, including regulatory compliance, maintenance of study documentation (regulatory binders, enrollment logs, Delegation of Authority logs), adverse event reporting, and participant registration in systems of record. Collaborate with Principal Investigators and study teams to implement new studies, develop key documents such as COI, DSMPs, and RDSPs, and troubleshoot study‑related challenges. Manage financial and operational aspects of trials, including tracking study milestones, documenting study payments and participant care expenses, supporting budget development, and assisting with study closeout activities. Serve as the primary liaison between sponsors, PIs, and study personnel, communicating effectively and professionally while ensuring timely responses to inquiries and study needs. Support data integrity and management, including use of EDC systems, resolving sponsor queries, identifying data issues, and ensuring completeness, accuracy, and security of research data. Lead and supervise research staff, including assigning work, managing performance, supporting professional development, conducting training, and ensuring compliance with protocols, SOPs, and regulatory requirements. Foster a collaborative and high‑performing team culture by promoting open communication, mentoring staff, setting measurable goals, and encouraging innovation and accountability. Ensure ethical conduct of clinical research, educating staff and participants on the distinction between clinical care and research, and reinforcing adherence to professional guidelines, regulatory standards, and institutional policies. Perform other related duties as assigned. Minimum Requirements Associate’s degree. Minimum of six years of research experience. A Bachelor’s degree may substitute for two years of required experience. Preferred Qualifications Oncology, hematology, or cellular therapy research experience. Clinical trials coordination experience. Experience in complex, multi‑protocol research environments. Management experience. Other Requirements Basic Life Support (BLS) certification from the American Heart Association or a Duke‑approved equivalent is required. Must maintain required certifications, training, and compliance with SOPs, regulations, and protocol requirements. Work Location Onsite. The work is performed on‑site within the Oncology Clinical Research Unit. Compensation and Benefits Annual base salary range: $69,362.00 to $110,658.00. Duke University provides comprehensive medical and dental care programs, generous retirement benefits, and family‑friendly and cultural programs for eligible team members. Equal Opportunity Employer Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy‑related conditions), sexual orientation, or military status. Essential Physical Job Functions Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and reasonable accommodation(s) can be requested with Duke Access and Accommodations Services (email: View email address on click.appcast.io; phone: View phone number on click.appcast.io). #J-18808-Ljbffr