Principal Software Engineer-Agentic AI
$115.4k - $192.3kRemitly
Are you a collaborative Agentic AI Engineer looking to work for a mission driven global organization? About the team: The Elsevier Healthcare Education (EHE) Data and Content Software Engineering team is responsible for building and maintaining scalable content ingestion pipelines that power critical health education products. Our work enables flagship platforms such as Sherpath and HESI, ensuring high-quality, reliable, and timely delivery of educational content to learners and educators worldwide. We focus on developing robust, efficient systems that transform and manage complex data, supporting innovation across Elsevier’s health education ecosystem. About the Role: We are seeking a Principal Software Engineer to join our team and play a key role in designing and delivering scalable, high-impact software solutions. In this role, you will lead the development of advanced content ingestion and processing systems, driving architectural decisions and engineering best practices across the team. You will collaborate closely with cross-functional partners, mentor engineers, and contribute to building resilient, high-performance platforms that support mission-critical products. This position offers the opportunity to influence technical strategy, champion innovation, and shape the future of content engineering within Elsevier Health Education. Requirements. Agentic AI & Advanced Tooling: • Experience designing, building, or integrating agentic AI systems (e.g., autonomous workflows, multi-step reasoning agents, AI copilots). • Hands-on experience with LLMs and orchestration frameworks (e.g., LangChain, OpenAI APIs, or similar). • Ability to design tool-augmented agents (function calling, retrieval-augmented generation, memory systems, planning/execution loops). • Experience with prompt engineering, evaluation, and guardrails for production-grade AI systems. • Understanding of AI system architecture, including latency, cost optimization, observability, and reliability of agent workflows. • Familiarity with vector databases, embeddings, and retrieval systems. • Experience integrating AI capabilities into enterprise systems and developer workflows. • Knowledge of responsible AI practices, including safety, bias mitigation, and governance. Responsibilities: Lead the design and development of agentic AI systems Architect and deliver autonomous workflows, multi-step reasoning agents, and AI copilots that solve complex business problems across the organization. Define and implement LLM-powered architectures Design scalable solutions leveraging large language models, orchestration frameworks (e.g., LangChain, OpenAI APIs), and modular service patterns to enable reusable AI capabilities. Build and optimize tool-augmented agents Develop agents that effectively utilize function calling, retrieval-augmented generation (RAG), memory systems, and planning/execution loops to perform reliable, context-aware tasks. Establish best practices for prompt engineering and evaluation Create standardized approaches for prompt design, testing, benchmarking, and continuous improvement to ensure high-quality outputs in production environments. Implement production-grade guardrails and safety mechanisms Design and enforce controls for hallucination mitigation, output validation, policy compliance, and safe execution of AI-driven workflows. Drive AI system performance and reliability Optimize latency, throughput, and cost efficiency of AI systems while ensuring high availability, observability, and fault tolerance across agent workflows. Design and manage retrieval systems Architect solutions using embeddings, vector databases, and hybrid search techniques to enable accurate, scalable knowledge retrieval. Integrate AI capabilities into enterprise platforms Embed AI services into existing products, APIs, and developer workflows, ensuring seamless interoperability with enterprise systems and data sources. Lead technical strategy and cross-functional alignment Partner with product, data, and engineering leaders to define AI roadmaps, prioritize initiatives, and align solutions with business objectives. Champion responsible AI practices Ensure systems adhere to standards for fairness, bias mitigation, transparency, and governance, while meeting regulatory and organizational compliance requirements. Mentor and elevate engineering teams Provide technical leadership, guide architectural decisions, and mentor engineers in building scalable, maintainable AI systems. Continuously evaluate emerging technologies Stay at the forefront of advancements in AI/ML, agent frameworks, and tooling, and drive adoption of innovations that create competitive advantage. Elsevier employs 10,000 people worldwide, including over 2,500 technologists. We have supported the work of our research and health partners for more than 140 years. Growing from our roots in publishing, we offer knowledge and valuable analytics that help our users make breakthroughs and drive societal progress. Digital solutions such as ScienceDirect, Scopus, SciVal, ClinicalKey and Sherpath support strategic research management, R&D performance, clinical decision support, medical education, and nursing education. Researchers and healthcare professionals rely on over 2,800 journals, including The Lancet and Cell; 46,000+ eBook titles; and iconic reference works, such as Gray's Anatomy. With the Elsevier Foundation and our external Inclusion & Diversity Advisory Board, we work in partnership with diverse stakeholders to advance inclusion and diversity in science, research and healthcare in developing countries and around the world. Elsevier is part of RELX a global provider of information-based analytics and decision tools for professional and business customers. U.S. National Base Pay Range: $115,400 - $192,300. Geographic differentials may apply in some locations to better reflect local market rates. This job is eligible for an annual incentive bonus. We know your well-being and happiness are key to a long and successful career. We are delighted to offer country specific benefits. Click here to access benefits specific to your location. We are committed to providing a fair and accessible hiring process. If you have a disability or other need that requires accommodation or adjustment, please let us know by completing our Applicant Request Support Form or please contact View phone number on click.appcast.io. Criminals may pose as recruiters asking for money or personal information. We never request money or banking details from job applicants. Learn more about spotting and avoiding scams here. Please read our Candidate Privacy Policy. We are an equal opportunity employer: qualified applicants are considered for and treated during employment without regard to race, color, creed, religion, sex, national origin, citizenship status, disability status, protected veteran status, age, marital status, sexual orientation, gender identity, genetic information, or any other characteristic protected by law. USA Job Seekers: EEO Know Your Rights. RELX is a global provider of information-based analytics and decision tools for professional and business customers, enabling them to make better decisions, get better results and be more productive. Our purpose is to benefit society by developing products that help researchers advance scientific knowledge; doctors and nurses improve the lives of patients; lawyers promote the rule of law and achieve justice and fair results for their clients; businesses and governments prevent fraud; consumers access financial services and get fair prices on insurance; and customers learn about markets and complete transactions. Our purpose guides our actions beyond the products that we develop. It defines us as a company. Every day across RELX our employees are inspired to undertake initiatives that make unique contributions to society and the communities in which we operate.
- ...strategies, establishes engineering standards, and... ...automation, CI/CD, and AI‑assisted development tools... ...modern environments. PRINCIPAL RESPONSIBILITIES AND DUTIES... ...generative and agentic AI tools to accelerate... ...experience across the full software development lifecycle...Suggested
- ...environments. Collaborate with architecture, data engineering, and platform teams to support multi‑... ...platform issues. Create and maintain software design documentation, DevOps process... ...controls in DevOps pipelines. Familiarity with AI/ML deployment pipelines and MLOps...SuggestedWork experience placementFlexible hours
- ...Boeing’s Digital Analytics and System Health Software team is seeking a talented and highly motivated Entry Level Software Engineer to join our team in Hazelwood, Missouri or Ridley... ...data scientists and developers to integrate AI capabilities. A successful candidate will...SuggestedHourly payFull timeContract work
$84.4k - $103k
Job Summary We are seeking an orchestration developer to design, build, and operate distributed execution platforms that support agentic, AI‑driven workflows and system‑to‑system coordination at scale. This role focuses on building reliable, asynchronous systems that enable...SuggestedShift work$142.8k - $207k
...repeatable, and efficient migrations. Collaborate with architects, engineers, product teams, security, operations, customers, and other... ...traditional data center to cloud. Experience in Artificial Intelligence (AI) technologies. Experience in cloud computing architecture and...Suggested- ...strategy, contributing to intelligent automation initiatives and AI enabled solutions. The ideal candidate is a hands on... ...Bachelor’s degree in Computer Science, Information Technology, Engineering, or a related field, or equivalent practical experience._______...Work at office
$84 - $120 per hour
...is currently seeking a talented Senior AI Engineer and Advisor. Do you have experience building... ...Skills & Experience 10+ years of software engineering experience, with at least 3... ...LLM‑based applications, including RAG, agentic patterns, structured generation, and prompt...Immediate start- ...ask for an accommodation or an alternative application process. Software Engineer - Frontend Full Time Technical Florissant, MO, US 6 days ago... ...+ CloudFront) Managing llms.txt standards and designing with AI discoverability ("AI SEO") in mind alongside traditional search...Full timeFor contractorsWork at office
- Vivos Holdings Llc is seeking a Cloud & Automation Architect to enhance our enterprise cloud platform with a focus on Azure operations. The position requires designing, implementing, and maintaining Azure infrastructure and governing cloud services effectively. The ideal...Work at office
- ...We are seeking a Software Engineer to design, develop, and maintain software that powers automated saw systems used in the truss and building... ...code and thoughtful system design over quick fixes. We embrace AI‑augmented development practices (e.g., GitHub Copilot and similar...Temporary workWork at office
- Boeing in Hazelwood is seeking Associate or Mid-Level Product Security Engineers to lead and support research projects applying advanced AI/ML technology to cyber security. The successful candidate will develop new concepts and lead initiatives that enhance Boeing's Cyber...Relocation package
- World Wide Technology is seeking an orchestration developer to design and build distributed execution platforms that support AI-driven workflows. The role involves developing reliable asynchronous systems for multi-step execution and agent collaboration. Candidates should...
- A leading aerospace company is seeking an Entry Level Software Engineer for a contract position in Hazelwood, Missouri. The role involves designing and integrating AI capabilities within internal platforms. Candidates should have a Bachelor's degree in a relevant field...Contract work
$136.85k - $185.15k
...future with us. The Boeing Company is currently seeking a Lead Software Engineer - DevSecOps to support our Phantom Works Virtual Warfare... ...warfighters-leveraging on-premises systems, cloud, containers, AI/ML, and high-performance computing to accelerate innovation....Permanent employmentWork experience placementInterim roleWork at officeRelocationVisa sponsorshipWork visaRelocation packageFlexible hoursShift workDay shift- A technology firm is seeking an Experienced Software Developer for their Manufacturing Quality IT Team in Hazelwood, MO. This contract role involves full stack development of Manufacturing Quality applications. Candidates should have over 5 years of software development...Hourly payContract work
- MiTek Industries in Chesterfield, MO is looking for a Software Engineer to design and evolve software solutions in the building industry. You... ...products. The role emphasizes continuous improvement, utilizing AI-assisted development and modern tools. Qualifications include...
- ...Description Description: Soleo Health is seeking a Senior Software Engineer in Frisco, TX or St. Louis, MO to design, develop, and... ...across frontend and backend ~ Experience using AI-assisted/agentic coding tools (e.g., coding agents) to accelerate development...Immediate startMonday to Friday
- ...on‑site. Overview Client is seeking a highly skilled DevSecOps Engineer to design, build, and operationalize secure, automated delivery... ...configuration, and deployment workflows for COTS applications. Apply AI‑assisted code analysis, test generation, and pipeline...Local area
$160.65k - $217.35k
Senior AWS Software Data Engineer - The Boeing Company The Boeing Company is looking for a Senior AWS Software Data Engineer to join our Digital Analytics and System Health (DASH) software team in Hazelwood, MO. The role focuses on designing, implementing, and scaling...Work experience placementInterim roleRelocationFlexible hours- MiTek Industries is seeking a Software Engineer in Earth City, Missouri. In this hybrid position, you will design and develop software that drives automated saw systems in the building materials sector. The role requires strong programming skills, particularly in .NET and...
- A leading technical consulting firm is seeking an experienced Data Scientist for a remote position. This role involves implementing advanced Machine Learning solutions, managing MLOps practices, and engaging directly with clients. A minimum of 4 years of experience in ML...Remote job
$67k - $136.8k
...solutions. We are looking for Fullstack Engineers who will collaborate with clients to... ...integrate, test, and deploy distributed software applications. You will deliver high qualify... ...in capital markets. Enabled by data, AI and advanced technology, EY teams help clients...Full timeSummer holidayFlexible hours- ...Software Developer Job Title: Software Developer Job Type: Full-Time Start Date: 2026-05-26 End Date: 2026-06-26 No Of Openings: 3 Salary... ...’s degree in Computer Science/Information Technology/IS/Engineering (Any) or closely related field with Twelve (12) months of experience...Full timeRelocation
$105k - $128.14k
...business where your contributions truly matter. Position Tapestry Solutions, a part of Boeing Global Services (BGS), is seeking a Software Engineer in Maryland Heights, MO . In this role you will develop C# software for the MQ-28 program, following a Scaled Agile Framework...Permanent employmentWork experience placementInterim roleWorldwideRelocationVisa sponsorshipWork visaFlexible hoursShift workDay shift$126.66k - $171.35k
..., with great opportunity for professional growth. Find your future with us. About the team The Boeing Company is looking for Software Engineers (Experienced, Senior) for a Phantom Works Proprietary program located in Berkeley, MO . This position will focus on developing...Permanent employmentWork experience placementInterim roleRelocationRelocation packageFlexible hoursShift workDay shift$105k - $140k
...small business where your contributions truly matter. Tapestry Solutions, a part of Boeing Global Services BGS, is seeking a Software Engineer in Hazelwood, MO for the Department of Navy Tomahawk Land-Attack Missile program. The Tomahawk program is expanding to include...WorldwideRelocationVisa sponsorshipWork visaRelocation packageFlexible hoursShift workDay shift$133k - $160k
...Senior Software Engineer – Maryland Heights, MO This role involves software development for the next generation Mission Planning system for the Department of Defense. You will be a member of a software development scrum team and follow the SAFe Agile software development...Interim roleFlexible hoursShift workDay shift$133k - $160k
...Senior Software Engineer – Maryland Heights, MO We are looking for a Senior Software Engineer to support future franchise programs and develop next‑generation Mission Planning system for the Department of Defense. The role involves software development in an Agile Scrum...RelocationVisa sponsorshipWork visaRelocation packageFlexible hours$82k - $115k
...Description As a member of the R&D organization responsible for creating software for the development of innovative in vitro diagnostic solutions, the Senior Software Engineer contributes to the design and delivery of scalable, cloud-native software solutions by implementing...Temporary workWork from home2 days per week3 days per week$126.66k - $171.35k
...Software Engineer (Experienced, Senior) The Boeing Company is looking for Software Engineers for a Phantom Works proprietary program located in Berkeley, MO. The position focuses on developing Vehicle Management System (VMS) software to support Boeing Defense, Space &...Work experience placementRelocation package
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Software Engineer-Agentic AI. Be the first to apply!
- software support Maryland Heights, MO
- software sales Maryland Heights, MO
- remote software sales Maryland Heights, MO
- software technical support Maryland Heights, MO
- software Maryland Heights, MO
- senior c# .net software developer Maryland Heights, MO
- entry level software sales Maryland Heights, MO
- healthcare software sales Maryland Heights, MO
- id software Maryland Heights, MO
- software implementation project manager Maryland Heights, MO

