Head, Health System Strategy, Rare Diseases (Somerville)
$232.5k - $335.83kSanofi
Job title: Head, Health System Strategy, Rare DiseasesLocation: Cambridge, MA7 Products + 2 Launches$2.2B $3.1B (2030)2 Direct ReportsIncluding landmark AATD Therapy, 1H 2027, VENG 2H 2026About the jobJoin the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Head, Health System Strategy, Rare Diseases within our US Rare Disease Leadership Team, you'll lead provider-focused strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll build strategic partnerships with health systems and IDNs, optimize care pathways, and accelerate patient diagnosis and treatment access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started?You'll be joining Sanofi's US Rare Disease business at a pivotal moment—managing a portfolio with clear growth trajectory to $3.1B by 2030, leading health system strategy for breakthrough therapies, and shaping how we partner with leading academic medical centers and integrated delivery networks to transform patient outcomes.About SanofiWe're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.Main responsibilities:Health System Strategy & Care Pathway OptimizationLead integrated health system strategy to accelerate diagnosis, optimize care pathways, and improve treatment access across the rare disease portfolioIdentify barriers across the patient journey—diagnosis, referral, treatment initiation, reimbursement—and develop targeted, scalable solutionsLeverage patient journey analytics, health economics, and real-world evidence to guide pathway strategy and institutional engagementChampion launch readiness for the landmark AATD therapy (1H 2027) across provider and health system dimensionsCollaborate with Health System leads across business units; share best practices and leverage common resourcesInstitutional Partnership & Shared Value StrategyIdentify the shared strategic priorities—the main thing—between Sanofi Rare Disease and senior institutional leaders, finding the intersection where patient access goals align with the institution's own clinical, operational, and outcome objectivesBuild trust-based, mutually beneficial partnerships with health system executives, department chairs, and medical directors that go beyond transactional engagement toward genuine value co-creationDesign and execute collaborative frameworks where Sanofi and institutional partners work toward a common purpose: getting the right rare disease patients diagnosed and treated fasterEngage senior stakeholders at leading academic medical centers and IDNs to uncover and activate shared opportunities that benefit patients, providers, and the health systemNavigate Legal & Compliance requirements for all health system partnerships and B2B solutions, ensuring all engagements are structured for sustainability and integrityProvider Partnerships & B2B SolutionsBuild strategic partnerships with health systems, IDNs, and provider organizations across the rare disease landscapeDesign B2B solutions that address health system needs across health information technology (HIT), operations, and patient experienceExpand key opinion leader relationships to uncover value-creation opportunities and advance rare disease awareness and diagnosisCross-Functional Leadership & CollaborationServe as the US Leadership Team subject matter expert on health system dynamics, care delivery trends, and provider engagement strategyIntegrate health system considerations into launch planning, lifecycle management, and portfolio strategyMonitor the competitive landscape and evolving care delivery models in partnership with Business Insights & SolutionsBuild, develop, and lead a high-performing team of 2 direct reportsAbout youRequired:Bachelor's degree required; advanced degree (MBA, MPH, MS, PhD) strongly preferred10+ years of experience in pharma, biotech, healthcare (medical center or large practice), or payer environment7+ years of leadership experience managing teams and cross-functional initiativesDemonstrated expertise in health system/provider strategy and partnerships with IDNs, health systems, and medical groupsProven track record in care pathway optimization and patient journey analyticsStrong business acumen with understanding of health system economics and B2B solutionsExcellent communication skills with ability to influence and negotiate at the executive levelAbility to navigate complex, highly regulated environments while managing multiple prioritiesPreferred:Experience in rare disease or specialty therapeuticsTrack record with organized customers and health system partnershipsExperience with patient journey analytics, health economics, and real-world evidenceProduct launch experience, particularly in rare disease or specialty settingsExperience with HIT integration and operational solutions for health systemsWhy choose us?Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Lead health system strategy for a high-growth $2.2B rare disease business with a clear path to $3.1BPlay a pivotal role in launching a landmark AATD therapy that will transform patient livesJoin the US Leadership Team and shape strategy across the entire rare disease portfolioPartner with leading academic medical centers and health systems to co-create patient valueWork at the intersection of innovation, patient access, and institutional partnershipBe part of a mission-driven team chasing the miracles of science to improve patients' lives.Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SG #LI-GZ #LI-HYBRID#vhdPursue progress, discover extraordinaryBetter is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!US and Puerto Rico Residents OnlySanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.North America Applicants OnlyThe salary range for this position is:$232,500.00 - $335,833.33All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.SummaryLocation: Cambridge, MAType: Full time
$266.25k
...Job Title: US Medical Head, Rare Blood DisordersLocation... ...challenges, rare diseases, cancers, and neurological... ...on the medical brand strategy, collaborating closely... ...understanding of the immune system – and innovative... ...Collaborate with the health economic teams and Medical...SuggestedFull timePart timeLocal area$206.25k - $343.75k
...Clinical Research Director - Rare DiseasesLocation:... ...Research Director (CRD), Rare Diseases Therapeutic Area, is... ...clinical development strategy for assigned projects/... ...of the immune system – and innovative pipeline... ...regulatory approvalEngage with health authorities (contribute...SuggestedFull timePart time$232.5k - $387.5k
...Job Title: Medical Head, Early Pipeline, Specialty... ...immune challenges, rare diseases, cancers, and neurological... ...disease and assets strategies. About Sanofi:We’re an... ...understanding of the immune system – and innovative... ...with a wide range of health and wellbeing benefits...SuggestedFull timePart timeLocal area$232.5k - $335.83k
...Job Title: Global Head of Clinical Data and Business StrategyLocation... ..., supporting our Play to Win strategy to become more focused,... ...pillars: Clinical Data Technology, Systems/Tools/Processes, and Business... ...generated data from wearables, mobile health applications, and other...SuggestedFull timePart time$266.25k - $384.58k
...Job Title: NA Medical Head TransplantLocation: Cambridge, MA, Morristown... ...lead transformative medical strategies that directly impact patient... ...understanding of the immune system – and innovative pipeline –... ...understanding of and ability to integrate health economics research into...SuggestedFull timePart timeWork at officeWorldwide$197.2k - $266.8k
...position reports to the head of the Clinical Data... ...CRO outsourcing strategy and deliverables, including... ...for clinical data systems including 21 CFR Part... ...support your overall health and well-being. We offer... ...lives of people with rare and common diseases. Built on Nobel Prize...Full timeTemporary workPart timeLocal areaFlexible hours- ...that deliver the development strategies for therapeutic compound(s) under... ...the specific therapeutic and disease area(s) of assignment.... ...in protocol-related KOL and Health Authority interactionsEnsures... ...-malignant hematology and/or rare diseaseProven track record of...Full timeTemporary workPart timeLocal areaFlexible hours
$280k - $420k
...adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. As a global leader in myostatin biology, a field... ...development projects. Responsible for providing safety strategy, expertise, and guidance, pre- and post-approval...Full timeContract workPart timeLocal areaFlexible hours$259.3k - $350.8k
...which spans a number of disease areas including kidney... ...overall clinical development strategies for the programs and to... ...Clinical Research TA head.This position is hybrid... ...support your overall health and well-being. We... ...the lives of people with rare and common diseases. Built...Full timeTemporary workPart timeLocal areaFlexible hours$206.25k - $343.75k
...Lead in charge of the clinical strategy. In addition, the CRD is... ...understanding of the immune system – and innovative pipeline – enables... ..., DSUR, Briefing Package for Health Authorities).Participates in... ...deep understanding of the disease.Clinical research or pharmaceutical...Full timePart timeRemote work$255k - $345k
...expanding portfolio, which spans from rare genetic to common diseases.The successful candidate’s primary... ...in the overall clinical development strategies for the molecules and drive progress... ...is designed to support your overall health and well-being. We offer comprehensive...Full timeTemporary workPart timeWork at officeLocal areaFlexible hours2 days per week- ...that deliver the development strategies for therapeutic compound(s) under... ...the specific therapeutic and disease area(s) of assignment.May... ...external stakeholder (e.g., Health Authority and Independent Ethics... ...the lives of people with rare and common diseases. Built on...Full timeTemporary workPart timeLocal areaFlexible hours
- ...muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. As a global leader in myostatin... ...activities in alignment with corporate strategy. This position requires a highly... ...BLAExperience interacting with health authorities in the US and EUIn-...Full timePart time
$164k - $199k
...Proficiency in trial management systems, IVRS/IWRS, eTMF, EDC,... ...is a plus Current rare disease experience and/or gene... ...trial operational strategy and updates to... ...recently, Navreet was Head of Global Clinical Operations... ...to support the health, wellness, and financial...Full timeContract workLocal area- ...deep understanding of the immune system – and innovative pipeline –... ...leadership of the Global Project Head, with the Global safety... ...representatives to deliver development strategy and prepare/assist with... ...and answer to questions from health authorities. Be the scientific...Part timeLocal area
$236.25k - $393.75k
...Therapeutic Area, you will lead the clinical trial strategy for one or more multiple myeloma assets,... .... Our deep understanding of the immune system – and innovative pipeline – enables us to... ...and your family, with a wide range of health and wellbeing benefits including high-...Full timePart time$175.8k - $237.8k
...Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical... ...with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has...Full timeTemporary workPart timeLocal areaFlexible hours$210.9k - $379.2k
...This role will report to the Head of Early Clinical Development,... ...ScientistsScientific Leadership, Direction and Strategy: Employs visioning and... ...provide expert leadership of disease/therapeutic area specific... ..., mindfulness, and mental health supportFamily planning benefits...Part timeWork at officeWork from home$174k - $212k
...programs, each targeting a disease with well‑understood... ...to lead clinical data strategy and execution across gene... ...has experience in rare disease clinical trials... ...multi‑cohort studies). Systems & Infrastructure Contribute... ...package with robust health, financial, and wellness...Full timeTemporary work- ...Safety, and Regulatory to ensure alignment of data management strategies with overall clinical development goals. Provide oversight... ...Expert-level proficiency with Medidata Rave EDC, including system configuration, form design, and edit check programming. Strong...Part timeWork at office
$177k - $278.08k
...critical quality issues, and mitigation strategies, while leading inspection readiness across... ...for Clinical Trial Delivery and PV Systems by sharing insights, lessons learned, and... ...and QualificationsScientific or allied health/medical degree (BSc required; MSc or PhD...Minimum wageFull timeTemporary workPart timeLocal areaWorldwide$243.1k
...integrated and innovative clinical development strategy to support the creation and management of... ...thinking to provide expert leadership of disease/therapeutic area specific strategy for a... ...to fitness, mindfulness, and mental health supportFamily planning benefits, including...Part timeWork at officeWork from home$177k - $278.08k
...Cambridge, MA reporting to the Head, Clinical Program Quality... ...commitment to provide Better Health and a Brighter Future to people... ...market by proactively reducing systemic compliance risks.Serve as a... ...quality issues, and mitigation strategies that safeguard program...Minimum wageFull timeTemporary workPart timeLocal areaWorldwide$196k - $285k
...genetically driven neuromuscular diseases. We are developing... ...the central nervous system (CNS) to address the... ...Affairs leads Dyne’s medical strategy and execution within... ...closely and with the Head of the Medical Science... ...PharmD) with experience in rare diseases; neuromuscular...Work at officeLocal areaNight shift- ...weeks ago Boston, MA $190,000.00-$250,000.00 3 days ago Head (Executive Director) Rare Disease, US Medical Affairs Cambridge, MA $296,000.00-$418,000.... ..., MA Executive Director, Quality Management and GxP Systems Director, International Sales and Marketing - Medical Device...Contract workRemote work
$327k - $360k
...demonstrated the potential for disease modification in... ...of the central nervous system and the eye that are caused... ...will report into the Head of Pharmacovigilance.... ...within the organization. Rare disease carries... ...building, developing medical strategies, contributing medical expertise...Temporary workFor contractors$152.6k - $283.4k
...program or studies within BR. May act as Focus/Disease/Platform Area Lead. May function as a... ...with key partners to set vendor strategy and timelines for assigned studies.Responsible... ...comprehensive benefits package that includes health, life and disability benefits, a 401(k)...Full timePart time$183.8k - $330.3k
...development team, contribute to regulatory and clinical program strategy, clinical trial design and clinical study execution. Author and... ...to well-being, with access to fitness, mindfulness, and mental health supportFamily planning benefits, including fertility, adoption,...Permanent employmentFull timePart timeWork at officeWork from home$130k - $150k
...seeking a Director, Clinical Information Systems, to lead the planning, governance, and optimization... ...clinical technology with organizational strategy, regulatory requirements, and clinician... ...'s degree in Information Systems, Health Informatics, or related field required; Master...$280k - $420k
...adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. As a global leader in myostatin biology, a field... ...development projects. Responsible for providing safety strategy, expertise, and guidance, pre- and post-approval...Contract workLocal areaFlexible hours
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