Research Associate - Gene Therapy Analytical Development 3663083

Job Description

Job Description

Be Part Of A High-Performing Team

Join a science-driven biopharmaceutical organization focused on developing innovative therapies for patients with serious and rare diseases. This opportunity sits within a Gene Therapy Analytical Development group responsible for building reliable analytical methods that support advancing gene therapy programs through development. The environment is highly collaborative and hands-on, bringing together analytical development, quality, bioinformatics, and regulatory expertise to solve complex scientific challenges.

What's In Store For You

• Engagement: W2 only (no C2C/1099)
• Gain hands-on experience supporting analytical method development for gene therapy programs.
• Work closely with experienced scientists while developing deeper expertise in molecular biology and viral vector analytics.
• Collaborate with cross-functional partners across QC, Bioinformatics, and Regulatory CMC.
• Contribute to assays that directly support the characterization and development of advanced therapeutics.

How You Will Make An Impact

• Develop, execute, and optimize viral genome titer assays using ddPCR and qPCR technologies.
• Design and evaluate primers and probes for specificity, sensitivity, precision, and reproducibility.
• Optimize PCR assay conditions, including cycling parameters, template concentrations, and inhibitor-related variables.
• Perform DNA and RNA extraction, purification, quantification, and sample preparation across multiple sample types.
• Apply restriction enzyme digestion and other molecular biology techniques to support assay development.
• Troubleshoot assay performance issues and conduct structured investigations into inconsistent or unexpected results.
• Analyze experimental data and maintain accurate technical reports, laboratory notebooks, and supporting documentation.
• Maintain laboratory records consistent with applicable GMP/GLP documentation practices.
• Partner with analytical development, quality, bioinformatics, and regulatory colleagues to advance gene therapy programs.
• Stay current with developments in ddPCR, molecular analytics, NGS, and gene therapy technologies.

Are You an Experienced Molecular Biology Research Associate Ready to Make an Impact?

• B.S. or M.S. in Molecular Biology, Biochemistry, Biotechnology, or a closely related life sciences discipline.
• Hands-on laboratory experience with qPCR and/or ddPCR , including assay setup, data interpretation, optimization, and troubleshooting.
• Experience designing and evaluating PCR primers and probes .
• Strong experience with DNA and RNA purification and quantification .
• Familiarity with restriction enzyme digestion and standard molecular biology or cloning techniques.
• Strong attention to detail with the ability to produce accurate, complete laboratory documentation.
• Ability to work effectively in a fast-paced laboratory environment while receiving scientific direction from senior team members.
• Strong written, verbal, analytical, and collaborative communication skills.
• Direct experience with Bio-Rad QX200, QXOne, or another ddPCR platform is highly desirable.
• Exposure to AAV or other viral vectors , analytical method development, GMP/GLP laboratories, NGS workflows, or JMP/statistical analysis is preferred.