Research Associate / Sr. Research Associate - Cell Therapy

Job Description

Job Description

About the Company:

BriaCell Therapeutics is a clinical-stage immuno-oncology company developing novel cell-based immunotherapies for solid tumors, including metastatic breast cancer. Our mission is to advance innovative immunotherapy approaches that improve outcomes for patients with difficult-to-treat malignancies.

Bria-IMTTM, BriaCell’s lead candidate, was awarded Fast Track status by FDA and is being evaluated in a pivotal Phase 3 combination study for metastatic breast cancer (MBC). MBC is breast cancer that has spread to other tissues. Bria-IMTTM is a targeted cell-based immunotherapy.

Bria-OTSTM, a platform of personalized off-the-shelf cell-based immunotherapies, is being evaluated in a Phase 1/2 clinical study initially targeting breast cancer, with extension to prostate cancer, and other cancers.

Learn more at: BriaCell | Advancing Cancer Immunotherapy Treatment

About the Position:

We are seeking a motivated Research Associate / Senior Research Associate to join our research and development team in Philadelphia, PA. This position offers the opportunity to contribute to the development of novel cell-based immunotherapies in a dynamic, collaborative biotechnology environment.

The successful candidate will work closely with senior scientists and cross-functional teams to execute laboratory studies, support preclinical development activities, and contribute to the advancement of BriaCell's immuno-oncology pipeline. This is a hands-on laboratory position requiring strong technical expertise, independent problem-solving skills, and the ability to manage multiple priorities in a fast-paced environment.

Responsibilities:

• Independently plan, execute, troubleshoot, and analyze laboratory experiments supporting the preclinical development of cell-based immunotherapeutic candidates.

• Perform in vitro studies using tumor cells, immune cells, and other relevant cellular models to evaluate therapeutic activity and biological mechanisms.

• Conduct immunological and cell-based assays, including multicolor flow cytometry, cytotoxicity assays, cytokine release assays, and cellular proliferation assays.

• Maintain and expand mammalian cell lines and primary cell cultures using established aseptic techniques.

• Support genetic engineering studies involving transfection, transduction, and other molecular biology techniques, as appropriate.

• Develop, optimize, and troubleshoot experimental protocols and analytical methods to improve assay performance, reproducibility, and reliability.

• Analyze experimental data, interpret results, identify trends, and communicate findings and recommendations to scientific leadership.

• Maintain accurate, complete, and timely laboratory records, experimental documentation, and data in accordance with established procedures and Good Documentation Practices.

• Collaborate with research, manufacturing, quality, and other cross-functional teams to support development objectives and project timelines.

• Contribute to the preparation of technical reports, scientific presentations, posters, manuscripts, and documentation supporting regulatory submissions.

• Assist in training and provide technical guidance to junior research associates, as needed.

• Support laboratory operations, including equipment maintenance, inventory management, reagent preparation, and compliance with laboratory safety procedures.

Qualifications:

Education and Experience

• Bachelor's or master’s degree in Immunology, Cell Biology, Molecular Biology, Biotechnology, or a related scientific discipline with 2 – 4+ years of relevant laboratory experience.

• Prior experience in biotechnology, biopharmaceutical research, or an academic research environment focused on immunology, oncology, or cell-based therapeutics.

• Demonstrated ability to independently execute experiments, troubleshoot technical challenges, and analyze complex scientific data.

Technical Skills and Knowledge

• Strong hands-on experience with mammalian cell culture, including established cell lines and primary cells.

• Proficiency in immunological and cell-based assays, including flow cytometry, cytotoxicity assays, cytokine release assays, and cell proliferation assays.

• Experience with experimental design, assay optimization, data analysis, and interpretation.

• Working knowledge of molecular biology techniques and cellular engineering approaches.

• Familiarity with laboratory documentation standards, experimental protocols, and scientific reporting.

• Proficiency with common laboratory data analysis and presentation tools.

Preferred Qualifications

• Experience in cell therapy, cancer immunotherapy, or immuno-oncology research.

• Hands-on experience with genetic engineering, transfection, and lentiviral transduction.

• Familiarity with Good Laboratory Practice (GLP), Good Manufacturing Practice (GMP), and Good Documentation Practices (GDP).

• Experience supporting preclinical development programs or preparing scientific documentation for regulatory submissions.

  To apply , To apply, please visit to and click on “About Us” and "Careers" and submit your application.

Equal Employment Opportunity Statement

BriaCell is an Equal Opportunity Employer. We are committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, pregnancy, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

Third-Party Agency Statement

BriaCell does not accept unsolicited resumes or candidate submissions from search firms, staffing agencies, or other third-party recruiters without a signed agreement in place. Any unsolicited resumes submitted to BriaCell, its employees, or hiring managers will be considered the property of BriaCell, and no fees will be paid in the event the candidate is hired.

\nCompany Description

BriaCell Therapeutics is a clinical-stage immuno-oncology company developing novel cell-based immunotherapies for solid tumors, including metastatic breast cancer. Our mission is to advance innovative immunotherapy approaches that improve outcomes for patients with difficult-to-treat malignancies.

Company Description

BriaCell Therapeutics is a clinical-stage immuno-oncology company developing novel cell-based immunotherapies for solid tumors, including metastatic breast cancer. Our mission is to advance innovative immunotherapy approaches that improve outcomes for patients with difficult-to-treat malignancies.