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Sr Scientist, Discovery Sciences and Technologies

$169.32k - $219.12k

Gilead

Responsibilities

  • Serve as subject-matter expert on ionizable lipid chemistry and tissue-selective mRNA delivery
  • Drive design, sourcing, synthesis, and evaluation of ionizable lipids and lipid libraries
  • Design and optimize mRNA-LNP formulations and targeted architectures for project needs
  • Execute high-throughput screening campaigns to evaluate transfection, cellular tropism, and immune activation
  • Establish LNP characterization workflows and quality control assays for discovery stage

Requirements

  • Ph.D. in pharmaceutical sciences, chemistry, chemical engineering, bioengineering, or biochemistry
  • 2+ years post-doctoral experience in LNP-based nucleic acid delivery
  • Hands-on expertise in mRNA-LNP formulation, lipid selection, microfluidic mixing, and LC-based analysis
  • Demonstrated proficiency with tangential-flow filtration purification methods
  • Experience designing high-throughput or design-of-experiments formulation screening campaigns
  • Ability to lead scientific projects independently and mentor junior scientists
  • Strong project management and cross-functional communication skills
Vacancy posted 21 days ago
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