Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Scientist, Systems Biology

BioSpace

Job Title: Senior Scientist, Systems Biology Location: Cambridge, MA About The Job As a Senior Scientist in Systems Biology within our Systems and Disease Biology Cluster, you will decode disease mechanisms at cellular resolution and pioneer AI-powered workflows that accelerate the path from discovery to patient impact. Ready to get started? The Systems and Disease Biology Cluster, part of the Target, Disease, and Systems Biology function at Sanofi Research, is dedicated to delivering first-in-class medicines to patients. Our approach involves deconstructing disease mechanisms into cellular building blocks and advancing innovative therapeutics for the precise targeting of pathogenic cell types. We are in search of a highly skilled, independent, proactive, and well-organized Senior Scientist. The ideal candidate will possess expertise in complex cellular analytics, as well as strong data science skills to help build upon our current achievements and secure our future success. Experience in developing and deploying modern agentic analysis workflows to accelerate discovery timelines and create reusable analytical templates is highly valued. Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives. Main Responsibilities Analyze and leverage spatial and single-cell multiomic data to delineate pathogenic cell states and tissue microenvironments, generating actionable mechanistic insights and novel target hypotheses that directly inform drug discovery decisions. Design intelligent agentic workflows that streamline the deployment of innovative algorithms and computational models. Contribute to the evaluation and application of foundation models and virtual cell models to advance our understanding of disease biology. Collaborate closely with interdisciplinary and cross-functional teams, including biologists, chemists, data scientists, and other stakeholders. Lead and contribute to high-profile presentations and publications, ensuring effective communication of research findings and methodologies. Support the growth of the team by mentoring interns and junior scientists, sharing knowledge and fostering a collaborative research environment. About You PhD completed by August 2026 in systems biology, computational biology, computer science, applied mathematics, or a related field with 0-3 years of relevant academic or industry experience. Experience in analyzing cellular multiomic data in academia or industry using Python. Hands-on experience building or deploying agentic analysis workflows. Record of productivity, innovation, and impact, demonstrated through publications or patents. Strong communication, organizational, interpersonal, and teamwork skills, with a successful history of collaboration across analytical disciplines. Preferred Postdoctoral training experience. Familiarity with or interest in addressing challenges related to combinatorial synergy and tailored deployments of foundation and virtual cell models. Why Choose Us Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave. Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs. Help improve the lives of millions of people globally by making drug development quicker and more effective. Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affinitive Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SA #vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here. #J-18808-Ljbffr BioSpace

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Senior Scientist, Systems Biology in Cambridge, MA vacancy
  • $100.5k - $145.17k

    Job Title: Senior Scientist, Systems BiologyLocation: Cambridge, MAAbout the JobAs a Senior Scientist in Systems Biology within our Systems and Disease Biology Cluster, you will decode disease mechanisms at cellular resolution and pioneer AI-powered workflows that accelerate... 
    Senior
    Full time

    Sanofi

    Cambridge, MA
    17 hours ago
  • $115k - $209k

     ...Summary We are seeking a Principal Scientist to join Pioneering...  ...that today lives in the heads of senior strategic and translational leaders into autonomous systems that identify, evaluate, and prioritize...  ...Background in computational biology, bioinformatics, or a... 
    Senior
    Casual work

    Seres Therapeutics

    Cambridge, MA
    3 days ago
  • Sanofi in Cambridge, MA is seeking a Senior Scientist in Systems Biology to decode disease mechanisms at cellular resolution and develop AI-powered workflows that accelerate translation from discovery to patient impact. The role focuses on integrating spatial and single... 
    Senior

    BioSpace

    Cambridge, MA
    4 days ago
  • $160k - $220k

     ...structural sciences, chemical biology, and data science to drug...  ...Position Overview We are seeking a scientist who builds. As a member of a...  ...will turn them into agentic systems that reliably orchestrate our...  .... The role is offered at the Senior Scientist I or Senior... 
    Senior

    Antares Therapeutics

    Boston, MA
    2 days ago
  • $115k - $215k

     ...using state-of-the-art LC-MS systems—including nano-LC and Orbitrap...  ...across a wide variety of biological matrices (e.g. cells, tissues...  ...recommendations to project teams, senior leadership, and external...  ...organized, solutions-oriented scientist with the ability to manage multiple... 
    Senior

    Kymera Therapeutics

    Watertown, MA
    2 days ago
  • $126k - $234k

     ...Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal ScientistLocation: Cambridge...  ...programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK...  .... Essential requirements · Ph.D. in biology, bioengineering, pharmaceutical sciences... 
    Senior
    Full time

    Novartis

    Cambridge, MA
    17 hours ago
  • $143k - $214.5k

     ...innovative and strategic Principal Scientist, Molecular Cloning...  ...Partner closely with Molecular Biology, Delivery, Discovery, Sequencing...  ...findings, and recommendations to senior leadership. PROFESSIONAL...  ...laboratory information management systems (LIMS). Working knowledge of... 
    Senior

    Seres Therapeutics

    Cambridge, MA
    3 days ago
  • $148.5k - $214.5k

    Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsLocation: Cambridge, MAAbout the JobJoin Sanofi's Target, Disease and Systems Biology (TDSB) team and become a key contributor to our Disease Genetics and Genomics cluster.... 
    Senior
    Full time

    Sanofi

    Cambridge, MA
    1 day ago
  • $146k - $236k

     ...beyond.About the Role Pioneering Intelligence (PI) is building AI systems that accelerate translational decision making. This forward-...  ...Personally execute problems that require expert judgment: novel biology, new modalities, or high-consequence analyses Set quality... 
    Senior

    Seres Therapeutics

    Cambridge, MA
    3 days ago
  • $125k - $175k

     ...organism-scale models of living systems. Using proprietary molecular...  ..., and computational scientists works across this full stack...  ...biotherapeutic candidates. This is a senior, hands-on role at the intersection...  ...QualificationsPhD in cell biology, immunology, biochemistry,... 
    Senior

    Manifold Bio

    Boston, MA
    3 days ago
  • $126k - $181.5k

     ...recruiting a team of top-tier scientists to build this powerful and...  ...motivated and highly collaborative Senior Scientist to join FL129’s...  ...technical innovation in molecular biology and small molecule screening,...  ...Ph.D. in molecular biology, systems biology, chemical biology, or... 
    Senior
    Contract work

    Seres Therapeutics

    Cambridge, MA
    3 days ago
  • $145k - $161k

     ...targeting a disease with well-understood biology and a clearly defined clinical...  ...exceptionally driven, discovery-minded Senior Scientist to join our Platform Technology & Innovation...  ...engineering of RNA components for Prime Editing systems, while also applying molecular biology... 
    Senior
    Full time
    Temporary work

    Prime Medicine

    Cambridge, MA
    17 hours ago
  • $160k - $190k

     ...cell (SC)-islet differentiation. As a Senior Scientist, you will execute optimization experiments...  ...-on experience with closed systems (tube welder, sealer, single-use assemblies...  ...cultureWhat we’re looking forPhD in Stem cell biology, biochemical/biomedical Engineering or... 
    Senior
    Temporary work
    Immediate start

    Sana Biotechnology

    Cambridge, MA
    3 days ago
  • $129k - $203.1k

     ...is seeking a curious and collaborative Senior Scientist for our growing Translational PK/PD organization...  ...discovery strategy with a focus on biologics, protein therapeutics, and peptides.The...  ...data to build PKPD, PBPK, quantitative systems pharmacology (QSP), or other... 
    Senior
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    Boston, MA
    2 days ago
  • $126k - $160k

     ...seeking a highly motivated and experienced Senior Scientist to join our research team. The...  ..., FACS, MACS) from various tissues and biological samples.Execute in vivo mouse studies,...  ...confocal, live-cell, and high-content imaging systems.Strong quantitative data analysis,... 
    Senior

    Seres Therapeutics

    Cambridge, MA
    1 day ago
  • $180k - $258.5k

     ...is seeking a motivated and innovative (Senior) Scientist, Machine Learning to join our team. In...  ...and evaluated on high-quality, biologically and chemically meaningful dataDevelop...  ...through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted... 
    Senior

    Seres Therapeutics

    Cambridge, MA
    4 days ago
  • $100k - $180k

     ...assembling a multidisciplinary team to invent, build, and rapidly test innovative technologies for observing biological systems. We are looking for a scientist with deep hands-on experience in optics and vibrational spectroscopy to join the team and help turn promising... 
    Senior
    Full time
    Part time

    Seres Therapeutics

    Cambridge, MA
    4 days ago
  •  ...staffingfuture.comWe are seeking a highly motivated Senior Scientist to join our growing Chemistry and...  ...in organic chemistry, chemical biology, or biochemistry. This hands-on laboratory...  ...(UF/DF), and automated chromatography systems (e.g., AKTA FPLC).Characterize... 
    Senior

    Planet Pharma

    Boston, MA
    2 days ago
  •  ...Time Our Client is Looking an innovative Senior Research Scientist – Agentic AI for Drug Discovery to develop next-generation AI systems that transform scientific research and accelerate...  ...sciences organizations Background in biology, chemistry, or disease biology Experience... 
    Senior
    Full time

    SoTalent

    Boston, MA
    2 days ago
  • $192k - $265k

     ...and execution-oriented machine learning scientist to join our Model-Driven Design team. This...  ..., data strategies, and closed-loop systems that determine what we design, build, test...  ...:PhD in machine learning, computational biology, computer science, applied mathematics,... 
    Senior
    Work at office
    Shift work

    Generate Biomedicines

    Somerville, MA
    3 days ago
  • $145k - $161k

     ...targeting a disease with well-understood biology and a clearly defined clinical...  ...used to treat disease.Position SummaryThe Senior Scientist / Senior Engineer, LNP Process Development...  ...with defining and setting up equipment systems for LNP and TFF processesKnowledge of CMC... 
    Senior
    Full time
    Contract work
    Temporary work

    Prime Medicine

    Cambridge, MA
    17 hours ago
  • $70k - $113k

     ...people, tech experts, researchers, and systems analysts to advance our mission. As a not...  ..., collaborative, and innovative Senior Scientist to lead high-impact translational research...  ...neurodegenerative diseases, stem cell biology, functional genomics, and computational... 
    Senior
    Remote work
    Shift work

    Massachusetts General Hospital

    Boston, MA
    4 days ago
  • Prime Medicine is recruiting a Senior Scientist to join the Platform Technology & Innovation team in Cambridge, MA. You will...  ...design and engineer RNA components for Prime Editing systems, translating deep RNA biology expertise into platform-level advances with... 
    Senior

    Primemedicine

    Cambridge, MA
    2 days ago
  • Antares Therapeutics is seeking a senior scientist to lead the development of AI-enabled workflows for discovery. You will integrate LLM-driven...  ..., biologies, and computational teams, delivering multi‑agent systems that accelerate design‑make‑test‑analyze cycles. You will sit... 
    Senior

    Antares Therapeutics

    Boston, MA
    2 days ago
  • Prime Medicine is seeking an exceptionally driven Senior Scientist for the Platform Technology & Innovation team. This role focuses on RNA component design for Prime Editing systems, applying molecular biology and editing expertise to tackle platform-level challenges with... 
    Senior

    American Society of Gene & Cell Therapy

    Cambridge, MA
    3 days ago
  • Flagship Pioneering in Cambridge, MA seeks a (Senior) Scientist in Optical Technologies to design and test innovative optical and vibrational spectroscopy methods for observing biological systems. You will lead hands-on experiments across instrumentation, biology, and external... 
    Senior

    Flagship Pioneering

    Cambridge, MA
    4 days ago
  • $228k - $358k

     ...Scientist II / Senior ML Scientist, Cofolding and Structure-Aware ML Cambridge, MA USA; London, UK...  ...ML models, not only using pretrained systems. You will work with ML researchers, computational...  ...in machine learning, computational biology, computational chemistry,... 
    Senior
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    Cambridge, MA
    17 hours ago
  • Generate Biomedicines, a clinical-stage generative biology company, seeks a machine learning scientist to lead ML methods, data strategies, and closed-loop systems for protein design. You will partner with protein designers and wet-lab scientists to translate ideas into... 
    Senior

    Generate Biomedicines

    Somerville, MA
    2 days ago
  •  ...optimize protein purification and analytical methods to support biologics discovery and development. Design, develop, and optimize...  ...troubleshoot liquid‑handling platforms and laboratory automation systems for protein purification, sample preparation, and analytical workflows... 
    Senior

    Commonwealth Sciences, Inc.

    Boston, MA
    1 day ago
  •  ...platform integrates synthetic biology, RNA engineering, machine...  ...are seeking a highly motivated scientist to lead the development and execution...  ...are seeking an experienced Senior Scientist or Scientist with...  ...in relevant cellular systems. Develop scalable, plate‑based... 
    Senior

    C10 Labs

    Cambridge, MA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Scientist, Systems Biology. Be the first to apply!