Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Method Development Scientist II / Senior Scientist I - Small Molecule / Peptides

AbbVie

AbbVie Analytical R&D seeks a Method Development Scientist II to independently develop and optimize analytical methods for small molecule pharmaceuticals. The role spans preclinical through late-stage clinical programs, requiring expertise in chromatography, spectroscopy, and cross-functional collaboration with process chemistry and drug product development teams.

Responsibilities

  • Develop, test, and implement analytical control strategies and methods for drug discovery candidates
  • Apply separation and detection techniques to profile impurities in pharmaceutical products across cGMP manufacturing
  • Conduct method development, validation, and technical data generation to support regulatory requirements
  • Interpret multidisciplinary data and design follow-on experiments to advance projects through development pipeline
  • Collaborate with cross-functional teams including Process Chemistry, Drug Product Development, and Quality Assurance

Requirements

  • Bachelor's degree in Chemistry/Analytical Chemistry with 7+ years experience, or Master's degree with 5+ years experience
  • Strong analytical chemistry background with hands-on chromatography (HPLC, UPLC, GC) and spectroscopic technique experience
  • Expert proficiency in Waters Empower CDS and LIMS systems for electronic data management
  • Ability to develop and troubleshoot analytical methods with minimal guidance
  • Knowledge of organic structure, functional groups, and modern spectroscopic techniques for small-molecule analysis
  • Self-motivated, detail-oriented, with strong written and oral communication skills
Vacancy posted 17 days ago
Similar jobs that could be interesting for youBased on the Method Development Scientist II / Senior Scientist I - Small Molecule / Peptides in North Chicago, IL vacancy
  •  ...Analytical Research & Development (Analytical R&D) is a...  ...pipeline of innovative small molecule medicines and spans from...  ...a world-class team of scientists and leaders who will...  ...For the Scientist II position, we are seeking...  ...develop and optimize new methods and techniques to... 
    Senior
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    18 days ago
  • AbbVie in the United States seeks a Senior Scientist I-II to advance AI-enabled drug discovery across small molecules. You will identify, develop, and deploy computational hit generation methods, collaborating with chemists, biologists, and other cheminformatics experts... 
    Senior

    ABBVIE

    North Chicago, IL
    4 days ago
  •  ...is seeking a driven Senior Scientist II to support AbbVie’s drug discovery and development programs through the...  ...Additional expertise in peptide chemistry, structural...  ...mass spectrometric methods, including assays involving...  ...experience in small-molecule drug development.... 
    Senior
    Local area

    AbbVie

    North Chicago, IL
    18 days ago
  • $109.5k - $208.5k

    Senior Scientist I - II, Computational HitGen / LeadGen Full-time Salary Min...  ...drug discovery across our small molecule portfolio. The key responsibilities...  ..., and deploy innovative methods for computational hit...  ...target Contribute to development of methods / workflows for... 
    Senior
    Full time

    ABBVIE

    North Chicago, IL
    5 days ago
  •  ...Biologics Drug Product Development (Bio DPD), a part...  ..., conjugates, peptides etc.). AbbVie...  ...the position of Senior Scientist I, Biologics Drug...  .... Scientist I or II depending on...  ...characterization methods. Solid understanding...  ...synthetic molecules and/or genetic medicine... 
    Senior
    Full time
    Temporary work
    Local area

    AbbVie Inc.

    North Chicago, IL
    27 days ago
  •  ...Biologics Drug Product Development (Bio DPD), a part of Development...  ...(proteins, conjugates, peptides, neurotoxins etc.) and genetic...  ...candidate for the position of Senior Scientist II, located in North Chicago,...  ...), parenteral synthetic molecules and/or genetic medicine (AAV... 
    Senior
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    26 days ago
  •  ...AbbVie seeks a Senior Scientist to develop and deploy computational methods for AI-enabled hit and lead generation in small molecule drug discovery. This role requires expertise in machine...  ...-functional teams Contribute to development of workflows for predicting binding... 
    Senior

    AbbVie

    North Chicago, IL
    18 days ago
  •  ...Description For the Senior Scientist I – Peptide Analytical Chemistry position...  ...scientific research and development. You will independently...  ...and optimize analytical methods and techniques to generate...  ...Opportunities to support small-molecule projects may also arise.... 
    Senior
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    22 days ago
  • $141.5k - $268.5k

    Principal Research Scientist II, Computational...  ...within the Synthetic Molecule CMC organization...  ...discovery and development. From virtual screening...  ...-based atomistic methods, including...  ...address AbbVie’s small-molecule and synthetic...  ...teams, and senior leaders. Identify... 
    Full time
    Work experience placement

    AbbVie

    North Chicago, IL
    5 days ago
  •  ...Biologics Drug Product Development (Bio DPD), a part of Development...  ...(proteins, conjugates, peptides, neurotoxins etc.) and genetic...  ...candidate for the position of Senior Scientist II, located in North Chicago,...  ...), parenteral synthetic molecules and/or genetic medicine (AAV... 
    Senior
    Full time
    Temporary work
    Local area

    AbbVie Inc.

    North Chicago, IL
    more than 2 months ago
  •  ...Biologics Drug Product Development (Bio DPD), a part of Development...  ...(proteins, conjugates, peptides, neurotoxins etc.) and genetic...  ...candidate for the position of Senior Scientist II / Principal Scientist I,...  ...neurotoxins), parenteral synthetic molecules and/or genetic medicine (... 
    Senior
    Full time
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    1 day ago
  •  ...AbbVie seeks a Senior Scientist II or Principal Scientist I to lead biologics drug product formulation and process development within the R&D organization. The role involves designing development studies, managing scale-up and technology transfer, and collaborating across... 
    Senior

    AbbVie

    North Chicago, IL
    18 days ago
  •  ...leverages AI-enabled drug discovery across our small molecule portfolio. The key responsibilities of...  ...optimization   Qualifications Senior Scientist I : Degree in relevant field (...  ...commensurate to experience.  Senior Scientist II : Degree in relevant field (chemistry... 
    Senior
    Local area

    AbbVie

    North Chicago, IL
    16 days ago
  • $141.5k - $268.5k

    Principal Research Scientist II, Process Chemistry Full-time Salary...  ...responsible for the chemical development of AbbVie’s clinical...  ...substance modalities, including small molecules. The candidate must be able...  ...with subordinates, peers, and senior management. Mentor staff in... 
    Full time
    Work experience placement

    AbbVie

    North Chicago, IL
    2 days ago
  •  ...Senior Scientist II role supporting drug discovery through design and execution...  ...to guide compound development and regulatory submissions....  ...chromatographic and mass spectrometric methods including radiolabeled...  ...skills Preferred: peptide biotransformation expertise... 
    Senior

    AbbVie

    North Chicago, IL
    17 days ago
  • Principal Research Scientist I/II Or Associate Director, Process...  ...AbbVie's Research and Development Process Engineering...  ...to drive synthetic molecule candidates from concept...  ...peers and influencing senior leadership with your expert...  ...that expand AbbVie's small molecule formulation... 
    Senior
    Work experience placement

    AbbVie

    Great Lakes, IL
    5 days ago
  •  ...Process Engineering, a part of AbbVie R&D’s Development Sciences organization, is responsible...  ...and drug products, including small molecules and antibody drug conjugates (ADCs), throughout...  ...engineers, drug product development scientists, program managers, and regulatory... 
    Senior
    Work experience placement

    AbbVie

    North Chicago, IL
    22 days ago
  •  ...The candidate for this Senior Scientist position will be working...  ...Author and approve method documents for regulated...  ...bioanalysis support in the drug development process. Experience...  ...methods for small molecules, large molecules, and peptides. Experience with operating... 
    Senior
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    8 days ago
  •  ...approach includes the discovery and development of novel positron emission tomography...  ...imaging (MRI), and related imaging methods in drug discovery and development....  ...years of experience, depending on the Senior Scientist level (I or II) Demonstrated skills in the quantitative... 
    Senior
    Full time
    Temporary work
    Local area

    AbbVie

    North Chicago, IL
    3 days ago
  •  ...under Biologics CMC, Development Sciences, R&D. TCT...  ..., and innovative scientist with expertise in...  ...CMC and Synthetic Molecule CMC. The work...  ...laboratory research or method development,...  ...or equivalent.  Senior Scientist I : BS...  ...experience.  Scientist II : BS with 7+... 
    Senior
    Full time
    Temporary work
    Local area
    Flexible hours

    AbbVie

    North Chicago, IL
    1 day ago
  •  ...Senior Scientist position in the Regulated Bioanalysis group managing...  ...across the drug development lifecycle. Responsibilities...  ...management, method development, and regulatory...  ...bioanalytical methods for small molecules, large molecules, and peptides Familiarity with WATSON... 
    Senior

    AbbVie

    North Chicago, IL
    7 days ago
  • AbbVie is seeking a Principal Scientist II/Associate Director in Analytical Platform Sciences & Characterization within the tLNP CMC team...  ...therapeutics. You will partner with drug product development, process development, and external collaborators, mentoring scientists... 

    BioSpace

    North Chicago, IL
    2 days ago
  •  ...AbbVie seeks a Senior Scientist to develop and deploy machine learning models for molecular optimization in drug discovery. The role involves...  ...properties, then communicate results to guide small molecule optimization. Responsibilities Work with project teams... 
    Senior

    AbbVie

    North Chicago, IL
    15 days ago
  •  ...Process Engineers in Product Development Science & Technology support...  ...successful job performance.    The Peptide Process Engineer will...  ...project activities with a group of scientists within the individual’s area...  ...subordinates, peers, and senior management. Mentors and trains... 
    Full time
    Temporary work
    Work experience placement
    Local area

    AbbVie Inc.

    North Chicago, IL
    a month ago
  •  ...Job Description AbbVie's Product Development Science & Technology (PDS&T) organization...  ..., and creative Principal Research Scientist II to be a key contributor for our Process...  ...from troubleshooting, implementation of small-scale models to the development and application... 
    Local area

    AbbVie

    North Chicago, IL
    25 days ago
  •  ...Organization, a part of AbbVie’s Development Sciences organization, is...  ..., including synthetics molecules, antibody drug conjugates (ADCs...  ...experience in the biologics, peptides, ADC development and genetic...  ..., drug product development scientists, program managers, and regulatory... 
    Senior
    Full time
    Temporary work
    Work experience placement
    Local area

    AbbVie Inc.

    North Chicago, IL
    more than 2 months ago
  •  ...Principal Research Scientist I position, we...  ...to lead a small team within Analytical...  ...for synthetic molecule programs,...  ...and drug product development from early development...  ...in PAT method development, chemometrics...  ...serving as a senior PAT subject...  ...), therapeutic peptides, or related... 
    Local area

    AbbVie

    North Chicago, IL
    15 days ago
  • $125k - $195k

     ...therapeutics. We are dedicated to the development of these novel therapies to help patients...  ...a highly motivated and skilled Scientist II/Senior Scientist to join the Bioanalysis team...  ...limited to: laboratory notebook records, method qualification reports, and bioanalytical... 
    Senior
    Full time
    Relocation package
    Flexible hours

    Enlaza Therapeutics

    Mundelein, IL
    19 days ago
  •  ...seeking a highly motivated and experienced scientist to join our Quantitative, Translational...  ...role will support sample preparation, method development, bioanalytical assay operations, data...  .../ supervise team of 2-3 scientist/senior scientist Qualifications PhD in Biological... 
    Senior
    Full time
    Local area

    AbbVie Inc.

    North Chicago, IL
    more than 2 months ago
  •  ...point of contact for the internal project development teams, QA, Business Operations, and...  ...training requirements. Qualifications Senior Scientist I Requirements: Bachelor’s Degree or equivalent...  ...environment). Senior Scientist II Requirements: Bachelor’s Degree or... 
    Senior
    Contract work
    Temporary work
    Local area
    Shift work

    AbbVie

    North Chicago, IL
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Method Development Scientist II / Senior Scientist I - Small Molecule / Peptides. Be the first to apply!