Biological Scientist

General Information Name Biological Scientist Employment Type Temporary Position level Full-time Virtual/Remote? No Labor Category Scientific Date 26-Jun-2026 City Bethesda State Maryland Country United States Ref # 9247861931 Description & Requirements Description Biological Scientist - NIH - Bethesda, MD Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world. We are currently seeking a Biological Scientist with the National Institutes of Health in Bethesda, MD. This is a long-term contract position which offers: Competitive compensation and comprehensive benefit package Optional health, vision, and dental plans Paid leave (min 120 hours; prorated for part-time position) as well as 11 paid federal holidays and 401K plan. Access to NIH's unparalleled resources and niche scientific initiatives. Learn more about what Kelly can do for you at TASKS. The contractor shall: Design and optimize recombinant protein expression vectors for various host systems e.g., Mammalian/Expi293/CHO, Insect/Baculo Perform in silico design of chimeric proteins, including the strategic selection of fusion tags HIS, Fc , protease cleavage sites TEV, HRV-3C , and signal peptides Perform in vitro biochemical and biophysical assays to evaluate proteins and constructs (e.g., SDS-PAGE, Western Blotting, UV-Vis (NanoDrop), SEC-HPLC) Perform and evaluate recombinant protein-antibody interactions and identify biologically relevant findings (e.g., ELISA, BLI) Operate and maintain FPLC systems (e.g., Cytiva ÄKTA Pure/Start) and associated software (UNICORN). Operate high-throughput Biolayer Interferometry (BLI) and Surface Plasmon Resonance (SPR) instruments (e.g., Octet RH96, Carterra, LSA) Utilize specialized analytical software (e.g., Octet Analysis Studio, Carterra Analysis Software, GraphPad Prism) for advanced kinetic modeling and epitope binning determination Conduct structure prediction and modeling as needed to inform experimental design (AlphaFold) REQUIREMENTS. The contractor must have: Master's in Biology, life sciences or related field 7-8 years experience in biology or related field performing biological research functions in a research setting and laboratory environment. Demonstrate knowledge of proper laboratory disposal methods and safety procedures. Experience maintaining and utilize cell lines for protein expression, and perform downstream supernatant harvest, cell lysis, and clarification Expertise developing and optimize multi-step protein purification protocols to improve yield, purity, and stability using diverse purification and chromatography techniques

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