Lead Purification Scientist for Large Molecule Downstream
Denali-Therapeutics
Denali Therapeutics is seeking a highly qualified candidate to lead and validate purification processes for large molecule development. The role entails authoring IND/BLA sections, coordinating studies, and supporting manufacturing activities with contract manufacturers. The ideal candidate will have a PhD in relevant fields, along with extensive experience in process characterization and a proven track record in cross-functional collaboration. A competitive salary and benefits are offered. #J-18808-Ljbffr Denali-Therapeutics
$106k - $138k
Denali Therapeutics Inc seeks an Associate Scientist for its Purification Process Development team in South San Francisco. The successful candidate will support late-stage downstream process development for large molecules, including purification characterization and analytics...Suggested$159k - $207k
Denali Therapeutics Inc in South San Francisco is seeking a Scientist to lead purification processes for large molecule pipelines. The candidate will develop protocols and validate methods while collaborating across teams. A PhD in a relevant field and over 10 years of...Suggested$159k - $207k
...founded on the collaboration of leading scientists, industry experts, and... ...and validating purification processes, as well as authoring... ...BLA sections to support our large molecule pipeline. Responsibilities... ...Independently lead purification/downstream process characterization,...SuggestedContract workWork experience placementLocal area$147k - $191k
Denali Therapeutics Inc in South San Francisco seeks an experienced professional to lead mass spectrometry and characterization activities for large molecule CMC. The role involves developing strategies for product characterization, maintaining lab records, and overseeing...Suggested$147k - $191k
...translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that... ...therapeutics to patients. Responsibilities Lead internal large molecule CMC-focused mass spectrometry and extended characterization...SuggestedLocal area$106k - $138k
...founded on the collaboration of leading scientists, industry experts, and... ...Associate Scientist to join our Purification Process Development team.... ...responsible for supporting late‑stage downstream process development activities for our large molecule pipeline. Key...Local area- ...sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance... ...our clients. We currently have a role available for a Large Molecule Scientific Lead. Job duties include, but are not limited to, the following...Contract workLocal areaRelocation packageDay shift
- Cogent Scientific is seeking a Large Molecule Scientific Lead in South San Francisco to design and execute antibody-drug conjugates (ADC) linker studies. This role involves developing innovative linker designs, evaluating compatibility with various payloads, and collaborating...
- ...team of highly experienced scientists and managers who have... ...Scientist II to join the Downstream Development team as a Scale‑Up Laboratory Purification Leader. In this role, you will lead laboratory‑based scale‑up... ...Provide hands‑on leadership in large column packing (AxiChrom,...
$124.3k - $230.9k
Senior Scientist / Principal Scientist - Synthetic Molecule Analytical Chemistry We are seeking an experienced scientist... ...Ability to collaborate, learn, and lead in a CMC/cross‑functional environment... ...effective use of AI tools such as large language models. Relocation...Local areaRelocation package- PowerToFly is looking for a Senior Scientist II in South San Francisco to join the Downstream Development team. The role focuses on leading laboratory-based scale-up activities and optimizing downstream processes for biologic drug substances. The ideal candidate will have...
$124.3k - $230.9k
...We are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record... ...technical depth to join our Synthetic Molecule Analytical Chemistry (SMAC) group. This role... ...to collaborate, learn, and eventually lead in a CMC/cross‑functional environment. Ability...Local areaRelocation package$124.3k - $230.9k
...Overview We are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record of laboratory innovation and technical depth to join our Synthetic Molecule Analytical Chemistry (SMAC) group. The successful candidate will thrive at the bench and...Local areaRelocation package- Job Title : Oligonucleotide Scientist II Working Model : Fully on-site, South San Francisco... ..., oligonucleotide synthesis, purification, and characterization techniques. Strong... ...environments. Preferred experience in large molecule drug discovery, oligonucleotide...Local areaImmediate startMonday to Friday
- Cytokinetics, located in South San Francisco, is seeking a Senior Scientist to lead efforts in small molecule synthesis and process development. The ideal candidate will have a Ph.D. in Organic Chemistry with a focus on drug substance development. This role encompasses...
- Genentech is looking for a motivated Senior Scientist or Principal Scientist for its Synthetic Molecule Analytical Chemistry group in South San Francisco. This role involves designing analytical methods and collaborating across teams for drug discovery and development while...Relocation package
- Scientist II - Oligonucleotides South San Francisco, United States... ...automated synthesizers Perform purification and characterization of... ...scalable synthesis methods for lead compounds Support... ...therapeutic applications Exposure to large molecule drug discovery #J-18808-...
$36.97 - $51.73 per hour
Role: Oligonucleotide Scientist II Location: 1 DNA Way, South San... ...oligonucleotide therapeutics, large molecule drug discovery would be... ...for scaled‑up synthesis of lead molecules and coordinate material... ...chemistry, oligonucleotide purification and characterization using HPLC...Contract workFor contractorsLocal area- A leading biopharmaceutical company located in South San Francisco is looking for a Senior Scientist or Principal Scientist to join their Synthetic Molecule Analytical Chemistry group. The role requires a PhD in relevant sciences with industry experience and a proven track...Relocation package
$124.3k - $265.9k
Dormont Manufacturing Co is looking for a motivated Senior Scientist or Principal Scientist to join their Synthetic Molecule Analytical Chemistry group in South San Francisco, California. The ideal candidate will possess a PhD in relevant scientific fields and a record...$120k - $160k
...is developing precision-engineered small molecule therapies to address core drivers of neurological... ...teams. The ideal candidate is a rigorous scientist with strong molecular design &... ...target validation, hit identification, hit-to-lead, and lead optimization activities Partner...Local area- Alumis Inc. in South San Francisco is seeking a highly motivated Sr. Scientist I of Analytical Development to join their small molecule CMC team. This role focuses on supporting analytical development and quality control throughout clinical development. The ideal candidate...
$142.52k - $192.82k
Senior Scientist, Membrane Protein Biochemistry page is loaded## Senior Scientist, Membrane... ...protein (MP) targets and their purification with detailed analytical characterization... ...that increase the success rates of large-molecule and small-molecule therapeutic discovery...Flexible hours$120k - $160k
Tenvie Therapeutics, located in Brisbane, California, is seeking a motivated medicinal chemist for the Small Molecule Discovery team. The successful candidate will design and execute experiments to advance innovative small molecule therapeutics. Responsibilities include...- Scientist II - Oligonucleotides South San Francisco, United States... ...oligonucleotide synthesis, purification, and characterization, and will... ...therapeutic discovery and lead molecule progression. Operate, maintain... .... Experience with large molecule drug discovery , oligonucleotide...Long term contract
$124.3k - $265.9k
F. Hoffmann-La Roche AG is seeking a Senior Scientist / Principal Scientist specializing in synthetic molecule analytical chemistry in South San Francisco, California. The role involves troubleshooting analytical methods and contributing to regulatory submissions. Ideal...- ...Therapeutics, Inc. in South San Francisco is looking for an Associate Scientist to join our Protein Sciences team. The ideal candidate will be involved in developing protein production and purification strategies, facilitating therapeutic program transitions. This full-...Full time
$115k - $135k
Associate Scientist, Protein Sciences Headquarters Location... ...production and purification strategies to support... ...characterize these novel molecules. Additionally, you will... ...Support the lead selection process by developing... ...required. Expertise in large and small‑scale...Full timeRelocation- Position Overview Machine Learning Scientist / Senior Machine Learning Scientist building agents for applied small‑molecule drug design at Roche’s Computational Sciences Center of Excellence. Responsibilities Design, build, and apply agentic workflows and ML models to...Local areaRelocation package
- Position Title: Scientist I, Protein Purification & Expression Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug...Full time
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