Lead Purification Scientist for Large Molecule Downstream
Denali-Therapeutics
Denali Therapeutics is seeking a highly qualified candidate to lead and validate purification processes for large molecule development. The role entails authoring IND/BLA sections, coordinating studies, and supporting manufacturing activities with contract manufacturers. The ideal candidate will have a PhD in relevant fields, along with extensive experience in process characterization and a proven track record in cross-functional collaboration. A competitive salary and benefits are offered. #J-18808-Ljbffr Denali-Therapeutics
$159k - $207k
Denali Therapeutics Inc in South San Francisco is seeking a Scientist to lead purification processes for large molecule pipelines. The candidate will develop protocols and validate methods while collaborating across teams. A PhD in a relevant field and over 10 years of...Suggested- AbbVie is seeking a highly motivated Senior Scientist II to lead laboratory-based scale-up purification processes in South San Francisco. The ideal candidate will have strong expertise in downstream development, technology transfer, and hands-on experience with AKTA systems...Suggested
$147k - $191k
...translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that... ...execution of protein characterization activities in our large molecule CMC analytical development group.Key Accountabilities/Core...SuggestedLocal area$147k - $191k
Denali Therapeutics Inc in South San Francisco seeks an experienced professional to lead mass spectrometry and characterization activities for large molecule CMC. The role involves developing strategies for product characterization, maintaining lab records, and overseeing...Suggested$159k - $207k
...founded on the collaboration of leading scientists, industry experts, and... ...and validating purification processes, as well as authoring... ...BLA sections to support our large molecule pipeline.Key Accountabilities... ...lead purification/downstream process characterization,...SuggestedContract workWork experience placementLocal area- ...lives of patients while transforming your career. Principal Scientist - PKDM (Large Molecule Project Team Representative) What you will do Let’s do... ...conjugates, and other emerging modalities Leading team discussions around pharmacokinetics, biodistribution...Flexible hours
- ...team of highly experienced scientists and managers who have... ...Scientist II to join the Downstream Development team as a Scale-Up Laboratory Purification Leader. In this role, you will lead laboratory-based scale-up... ...Provide hands-on leadership in large column packing (AxiChrom,...Local area
- Amgen SA in South San Francisco seeks a Principal Scientist to lead pharmacokinetics and drug metabolism projects for large molecules. This role involves serving as a subject matter expert and provides strategic leadership across project teams. Ideal candidates will have...Flexible hours
$147k - $191k
Denali-Therapeutics is looking for a Senior Scientist in South San Francisco to lead analytical development of protein therapeutics. Candidates should hold a PhD and possess 3+ years of experience in CMC-focused analytical development. Applicants will be responsible for...$124.3k - $230.9k
Senior Scientist / Principal Scientist - Synthetic Molecule Analytical Chemistry We are seeking an experienced scientist... ...Ability to collaborate, learn, and lead in a CMC/cross‑functional environment... ...effective use of AI tools such as large language models. Relocation...Local areaRelocation package- A leading biopharmaceutical company in South San Francisco seeks a Senior Bioanalytical Scientist to design and execute bioanalytical strategies for discovery and preclinical development... ...bioanalytical methods for small molecules and antibody-drug conjugates, managing CRO...
$163.5k - $281.6k
...proof-of-concept, putting Lilly's industry-leading capabilities behind their missions. We... .... Prioritize opportunities that impact molecule quality, cycle time, and probability of... ...selection, human‑relevant pharmacology models, purification and formulation best practices and...Full timeFlexible hours$117k - $139k
Scientist, Analytical Development and Mass Spectrometry Position Overview Sutro Biopharma... ...to support analytical upstream, downstream, and formulation process development teams... ...experience in the characterization of large molecule biologics is required Experience with...Contract work$142.52k - $192.82k
Senior Scientist, Membrane Protein Biochemistry page is loaded## Senior Scientist, Membrane... ...protein (MP) targets and their purification with detailed analytical characterization... ...that increase the success rates of large-molecule and small-molecule therapeutic discovery...Flexible hours$120k - $160k
...is developing precision-engineered small molecule therapies to address core drivers of neurological... ...teams. The ideal candidate is a rigorous scientist with strong molecular design &... ...target validation, hit identification, hit-to-lead, and lead optimization activities Partner...Local area$120k - $160k
Tenvie Therapeutics, located in Brisbane, California, is seeking a motivated medicinal chemist for the Small Molecule Discovery team. The successful candidate will design and execute experiments to advance innovative small molecule therapeutics. Responsibilities include...$124.3k - $265.9k
F. Hoffmann-La Roche AG is seeking a Senior Scientist / Principal Scientist specializing in synthetic molecule analytical chemistry in South San Francisco, California. The role involves troubleshooting analytical methods and contributing to regulatory submissions. Ideal...- Scientist II - Oligonucleotides South San Francisco, United States... ...automated synthesizers Perform purification and characterization of... ...scalable synthesis methods for lead compounds Support... ...therapeutic applications Exposure to large molecule drug discovery #J-18808-...
$124.3k - $230.9k
Overview We are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record of laboratory innovation and technical depth to join our Synthetic Molecule Analytical Chemistry (SMAC) group. The successful candidate will thrive at the bench and solve...Local areaRelocation package$90k - $117k
...Denali is founded on the collaboration of leading scientists, industry experts, and investors who... ...the group with primary or secondary purifications and early analytical... ...the Protein Sciences team to prepare large-molecule biotherapeutics for preclinical in vivo...Full timeWork at officeLocal area- ...Scientific in South San Francisco is looking for an Expert Protein Biochemist to perform high-throughput molecular cloning, protein purification, and biophysical characterizations. This full-time day shift role requires a PhD in Biology or Biochemistry and offers...Full timeRelocation packageDay shift
- F. Hoffmann-La Roche AG is looking for a highly motivated Medicinal Chemist (Senior Principal Scientist) to lead a multidisciplinary team in the Peptide Therapeutics department. This role focuses on advancing peptide therapeutics from discovery through clinical development...
$129.2k - $240k
Genentech is seeking a highly skilled Computational Scientist in South San Francisco to join the Research Pathology Department. The role focuses on developing models and AI pipelines for spatial omics initiatives, requiring expertise in computer vision and advanced machine...- MSD Malaysia is seeking an Associate Principal Scientist in South San Francisco to contribute to innovative therapies for respiratory diseases. This role involves designing complex studies, integrating insights, and collaborating across teams to advance drug discovery....
$270k - $340k
Databricks is looking for a Principal Research Scientist - Scaling to lead a team in advancing large-scale machine learning methods. You will focus on optimizer design, low-precision training, and scalable architectures. Ideal candidates will have significant research leadership...- .... Hoffmann-La Roche AG is seeking an exceptional computational scientist in South San Francisco to enhance peptide therapeutic discovery... ...with 0-6 years of post-doctoral experience. This role involves leading model developments, contributing to platform design, and collaborating...Relocation package
$165k - $184k
A cutting-edge biotechnology firm in South San Francisco is seeking a highly motivated Principal Scientist in Bioanalytical to lead bioanalytical strategies. The ideal candidate will have a Ph.D. and over 8 years of experience in bioanalytical methods, including assay...- ...rigorous, and human-centered model evaluations. Leading enterprises and AI labs rely on our... ...is looking for a Machine Learning Scientist to lead our open-source research, including... ...looking for: Hands-on experience training large-scale models, including reward models, preference...Permanent employmentWork at officeWorldwide
- ...technology and CDMO company specializing in small molecule drug development, chemical synthesis,... .... Headquartered within one of China’s leading national biopharmaceutical industrial... ...R&D laboratories, synthesis centers, and large‑scale GMP production facilities supporting...Remote jobLong term contractContract workWorldwide
- A Bay Area biotechnology company seeks an experienced Computational Scientist to enhance virtual hit discovery and CADD initiatives. The successful candidate will collaborate with a diverse team to integrate advanced modeling and deep learning into drug development. Ideal...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Lead Purification Scientist for Large Molecule Downstream. Be the first to apply!
- safety scientist South San Francisco, CA
- image scientist South San Francisco, CA
- regulatory scientist South San Francisco, CA
- water quality scientist South San Francisco, CA
- senior principal scientist South San Francisco, CA
- pharmaceutical scientist South San Francisco, CA
- downstream processing scientist South San Francisco, CA
- remote scientist South San Francisco, CA
- genomics scientist South San Francisco, CA
- scientist biology South San Francisco, CA

