Associate Director, Externally Sponsored Research Contracts

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking an initiative-taking and detail-oriented individual to manage all aspects of Externally Sponsored Research (ESR) contracts, including Investigator-Sponsored Trial (IST) and Collaborative Research (CR) agreements, globally. The AD of ESR Contracts plays a pivotal role in the management of the contracts and budgets to ensure alignment with protocol specifications, ensuring compliance with company regulatory, and fair market value (FMV) standards are aligned. The successful candidate will serve as a key contributor and emerging leader, partnering closely with cross-functional teams including Medical Affairs, Finance and Legal reporting to the Director, Global Clinical Site Contracts. Additional responsibilities include:

• Lead the end-to-end negotiation, execution, amendment, and closeout of global ESR agreements, including Investigator-Sponsored Trials (ISTs), Collaborative Research (CR) agreements, and other externally sponsored research arrangements.

• Develop, review, and negotiate ESR budgets to ensure alignment with protocol requirements, internal funding guidelines, Fair Market Value (FMV) standards, and applicable regulations.

• Serve as the primary contracts liaison for Medical Affairs, Legal, Finance, Compliance, and other cross-functional stakeholders to facilitate timely agreement execution and funding decisions.

• Partner with Medical Affairs and research sponsors to evaluate contract and budget terms, identify risks, and recommend mitigation strategies while supporting business objectives.

• Ensure ESR contracting processes comply with company policies, industry regulations, transparency reporting requirements, and applicable local laws across global regions.

• Track and manage ESR contract lifecycle activities, including milestones, amendments, payment schedules, and reporting obligations, ensuring accurate documentation and audit readiness.

• Drive process improvements, standardization initiatives, and development of templates, playbooks, and best practices to enhance efficiency and consistency across ESR contracting activities.

• Monitor and analyze ESR contracting metrics, cycle times, and operational performance indicators, providing regular updates and recommendations to leadership.

• Support inspection and audit readiness by maintaining complete and accurate contract documentation and responding to internal and external audit requests.

• Provide guidance and mentorship to contract professionals and cross-functional stakeholders regarding ESR contracting strategies, budget development, and compliance requirements.

• Contribute to the development and implementation of departmental policies, procedures, and training programs related to externally sponsored research contracting.

• Stay informed of evolving industry practices, regulatory requirements, and market trends impacting externally sponsored research and investigator-sponsored studies.

• Represent the ESR Contracts function in cross-functional governance meetings, strategic initiatives, and continuous improvement projects.

Required Skills, Experience and Education:

• RN or bachelor’s or master’s degree in biological sciences or health-related field required.

• 11+ years direct clinical operations experience in the pharmaceutical or biotech industry. Relevant indirect experiences may also meet the requirement.

• Contract and budget negotiation experience with Institutions.

• Strong MS Word knowledge.

• Grant Plan for Investigators (GPI) or similar FMV assessment tool experience.

• Strong analytical and business communication skills.

• Ability to work effectively in a team/matrix environment.

• Ability to implement methods, techniques, procedures, and evaluation criteria to achieve results.

• Thinks strategically to anticipate future needs and success related to ESR contracting and FMV budget assessment.

• Strong organization skills.

• Understands ESR processes from proposal submission through study close-out.

Preferred Skills:

• Oncology experience.

• Biotech/pharma experience.

• CMS experience.

• Smartsheet experience.

• Knowledge in creating/managing spreadsheets. 

  #LI-Remote #LI-DN1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact View email address on click.appcast.io.

Base Pay Salary Range $177,000—$221,000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.


Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.


If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to View email address on click.appcast.io so we can share these impersonations with our IT team for tracking and awareness.