Scientific Manager, Translational Biology, CVRM
$115.9k - $215.3kF. Hoffmann-La Roche AG
The Opportunity A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech! Primary Responsibilities Provide scientific and technical hands-on support for research involving but not limited to in vivo and ex vivo studies in animal models of cardiovascular, renal, obesity, and metabolic conditions with the goal of progressing novel drug candidates into clinical development and beyond. Plan and execute experiments, develop and follow protocols, document data, troubleshoot problems, interpret data and communicate results, and maintain up-to-date knowledge in the fields. Advise on technical or project strategy as appropriate. Mentor and train junior members to be scientifically and technically proficient. Manage studies performed at CROs, evaluate the resulting data, develop technical documents and assist with the preparation and/or review of information supporting regulatory submissions. Work collaboratively within multidisciplinary project teams. Effectively communicate lab activities, timelines and results to team members and collaborators. Who You Are PhD in Pharmacology, Biology or other related field with 3+ years relevant post-graduate experience. Knowledge in the cardio-metabolic disease field with a strong in vivo background is essential. Hands-on experience with cardiovascular models (heart and kidney ischemia reperfusion injury, transverse aortic constriction) and phenotyping (echocardiography, heart catheterization) to answer questions about CVRM biology and drug discovery. A scientist with passion for hands-on research and desire to lead from the bench. Ability to multitask and contribute to several projects while remaining well organized. Ability to take unique and creative approaches to solve challenging problems. Good interpersonal skills and ability to work well with a multidisciplinary team and effectively communicate in cross-functional forums. Preferred Experience in rodent surgeries (in addition to cardiovascular), ex vivo experiments, and isolation of primary cells is a plus. Prior experience working in a biotech or pharmaceutical industry setting, understanding the demands and timelines of a drug discovery and development environment. Relocation and Compensation Relocation benefits are available for this job posting. The expected salary range for this position based on the primary location of South San Francisco, CA is $115,900 to $215,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. Who We Are Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world’s most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours. #J-18808-Ljbffr F. Hoffmann-La Roche AG
$115.9k - $215.3k
...Genentech! The Opportunity The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech... ...Primary Responsibilities Provide scientific and technical hands‑on support... ...and technically proficient. Manage studies performed at CROs, evaluate...ScientificLocal areaRelocation package$85.5k - $158.7k
The PositionThe Opportunity The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is... ...studies and prioritization.Familiar with relevant scientific literature. Understand and apply relevant...ScientificFull timeLocal areaRelocation package$111.8k - $207.6k
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...love. That’s what makes us Genentech!The Translational Genomics and Proteomics Center at... ...to advance our understanding of human biology and disease.A position is available in... ...mechanisms and therapeutic hypotheses.Drive scientific strategy and contribute to target identification...ScientificFull timeLocal areaRelocation package- ...Francisco is seeking a Scientist III to join Translational Medicine. You will help identify and... ...understanding across MS-related biology. The role demands expertise in human-relevant... ...systems, multi-omics data, and strong scientific communication to inform development and...Scientific
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...time with the people we love.Genentech's Translational Medicine OMNI (TM OMNI) team supports... ...translate data-driven insights into functional biology.Lead and coordinate exploratory... ...across the organization and the broader scientific community through high-quality reports,...ScientificFull timeLocal areaRelocation package$202.8k - $376.6k
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...patients worldwide. The OpportunityThe AI Biology & Translation (AIBT) department within Genentech's... ...logic that makes these systems scientifically useful, and the infrastructure, AgentOps... ...agent memory and context management for long-horizon workflowsModels and...ScientificFull timeLocal areaWorldwideRelocation package$175k - $200k
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$159.6k - $251.2k
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Scientist II - Translational Sciences (Contract) At Pliant, we believe... ...position will be to design and manage preclinical in vivo and in... ...required. PhD in Molecular Biology, Biochemistry, Immunology,... ...follow-through, and vigorous scientific curiosity Exceptional interpersonal...ScientificHourly payFull timeContract workFor contractorsFor subcontractorWork at officeImmediate startFlexible hours$143.2k - $265.9k
...a growing metabolism biology group at Genentech? Are... ...therapeutic development?The CVRM Discovery within... ...pharmacology, and clinical translatability. The incumbent will... ...driven, building and managing a team (approximately... ...and publish impactful scientific discoveries.Manage day...ScientificFull timeLocal areaRelocation package$136.9k - $254.2k
...that provides strategic leadership and scientific rigor across Development at Roche. Biostatistics... ...Cardiovascular, Renal, and Metabolism (CVRM), and Immunology portfolios—serving as a... ...trial operations with cutting-edge translational research. You will be responsible for...ScientificFull timeLocal area$169.32k - $219.12k
...development of life-changing scientific innovations. Our employees... ...clinical programs, from early translational research through Phase I-III... ...CRO oversight, vendor management, and data quality assurance.... ...in Immunology, Inflammation Biology, Translational Medicine, or...ScientificFull timeFor contractorsLocal area$135k - $175k
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$95.6k - $153k
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...landscapes, trends, and dynamics to translate high-level plans into... ...organizations ~ A track record of managing complex sales cycles within... ...technical requirements and scientific/regulatory use cases ~... ...much in common with physics and biology as with traditional efforts in...ScientificWork at officeVisa sponsorshipFlexible hours$43 - $64 per hour
...is also developing foundation models for biology and disease to enable better target... ...walkthroughs and coordinate equipment relocations Manage the onboarding setup and decommissioning... ...regulatory compliance Partner with scientific staff to identify and remediate safety...ScientificHourly payContract workRelocation
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