Principal Scientist II: Targeted Therapeutics & ADC Platforms
U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
Novartis Institutes for BioMedical Research, Inc. in Cambridge is seeking a highly motivated Principal Scientist to join the xDC team. This role involves advancing targeted therapeutic platforms, particularly biologics and drug-conjugates. The ideal candidate will possess strong scientific judgment and technical expertise, with industry experience in biologics or related modalities. Key responsibilities include driving scientific activities, designing experiments, and collaborating with cross-functional teams to support therapeutic development. A Ph.D. and relevant postdoctoral experience are required. #J-18808-Ljbffr U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
$126k - $234k
...Job Summary Band Level 4 – Principal Scientist II or Senior Principal ScientistLocation... ...accelerate oligonucleotide therapeutics (xRNA), including antibody‑... .... Collaboratively develop platform disease (QSP) and PBPK/PD... ...antibody‑drug conjugates (ADCs). Demonstrated ability to...PlatformPrincipal$126k - $234k
...Principal Scientist II Or Senior Principal Scientist Novartis is a leader in... ...accelerate oligonucleotide therapeutics (xRNA), includingantibody-xRNA... .... Collaboratively develop platform disease (QSP) and PBPK/PD... ...antibody-drug conjugates (ADCs) is strongly preferred. Collaboration...PlatformPrincipal$119.7k - $222.3k
...Principal Scientist This role is based in Cambridge, MA. Please only apply if this location... ...and help advance next-generation targeted therapeutic platforms. This role will contribute to thedevelopment... ...and scientific landscape in ADCs, biologics, and targeted...PlatformPrincipal$181.01k - $200.07k
...application process. Principal Scientist, Medicinal Chemistry... ...00 Annually About C4 Therapeutics: C4 Therapeutics (C4T... ...delivering on the promise of targeted protein degradation... ...its TORPEDO® platform to efficiently design... ...modalities, including ADC / DACs. Hands‑on experience...PlatformPrincipalFull timeContract work- ...utica in Cambridge, MA is seeking a highly motivated Principal Scientist to contribute to xDC and biologics platforms. The role involves working with cross-functional... ...industry experience, particularly in biologics or ADCs. The position offers a competitive salary and a...PlatformPrincipal
$130k - $160k
About Ratio Therapeutics Ratio Therapeutics is committed... ...a team of passionate scientists, engineers, and business... ...advancing the field of targeted radioligand therapy.... ...TRILLIUM™ and MACROPA™ platforms: TRILLIUM™ allows fine... ...is seeking a Scientist II, Process Development,...PlatformWork experience placementWork at office- ...; direct experience with Bruker Beacon platform required. Deep expertise in antibody cloning... ...managing and developing research scientists (preferred). Location / Work Setup Onsite... ..., wellness days, holidays, and two recharge breaks #J-18808-Ljbffr Scorpion TherapeuticsPlatformPrincipalFlexible hours
- ...Intelligence is seeking a Principal Scientist – Computational... ...approaches on high value targets. This position will... ...’s scientific platforms. Position Summary... ...cutting-edge antibody therapeutics across Flagship’s portfolio... ...-drug conjugates (ADCs), and antibody fragments...PlatformPrincipal
$166.77k - $202.09k
## Principal Scientist, AI-Driven Oncology Target DiscoveryCambridge Crossing - MA - USFind out how well you match... ...and development and across all therapeutic areas at BMS. We do this in close... ...design and scale advanced analytical platforms and agent-based systems that...PlatformPrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$156.18k - $189.25k
## Principal Scientist, Discovery BioSciences - Integrative New Targets, OncologyCambridge Crossing - MA - USFind out how well... ...development of novel oncology therapeutics for patients. Centered at our... ...leverage our multiple modality platforms to best match the modality to...PlatformPrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$108.5k - $201.5k
...the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...in discovery or clinical development to be considered for Principal Scientist II • Extensive and in-depth knowledge of pharmacokinetics...Principal$122.25k - $176.58k
...Job Title : Principal Scientist, Neurology Research, Cambridge MA Location: Cambridge, MA About... ...the above data sets to accelerate new target and biomarker discovery efforts. Join... ...harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. Why...PlatformPrincipalShift work$187.63k - $207.38k
...Job Description About C4 Therapeutics: C4 Therapeutics (C4T) (... ...delivering on the promise of targeted protein degradation science... ...leveraging its TORPEDO® platform to efficiently design and optimize... ...motivated and innovative Principal Scientist in Immunology to lead...PlatformPrincipal$103.5k - $115k
...leveraging its proprietary Prime Editing platform, a versatile, precise and efficient... ...diversified portfolio of investigational therapeutic programs organized around our core areas... ...on a set of high value programs, each targeting a disease with well-understood biology...PlatformFull timeTemporary work$165k - $200k
...unlocking biologically important targets long considered undruggable... ...? We are seeking a Principal Scientist with deep expertise in drug... ...formulation development for peptide therapeutics to play a critical role in... ...'s pipeline and delivery platforms from early development...PlatformPrincipalShift work$200k - $250k
...unlocking biologically important targets long considered undruggable... ...and self-motivated Senior Principal Scientist to be a versatile, hands-on... ...is part of Parabilis's platform discovery engine for... ...undruggable" genes of major therapeutic interest to patients. Key...PlatformPrincipalShift work- Seeking an accomplished and highly driven Principal Scientist to lead from the bench in-depth... ...-generation antibody-drug-conjugates (ADCs). This role is a critical lab-facing leadership... ...dynamics across multiple ADC therapeutic programs, ensuring alignment with program...Principal
$126k - $234k
...medicines for cancer patients through a combination of treatment approaches including targeted therapies, immunotherapies, CAR‑T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge, MA. The successful candidate...PrincipalRemote work- ...Principal Scientist, Analytical Sciences At Lilly, the work is demanding because patients are waiting... ..., we invite you to join us. Orna Therapeutics, Inc., a wholly owned subsidiary of Eli... ...-of-the-art expression and delivery platform positions us to tackle complex diseases...PlatformPrincipalContract work
$137k - $215.27k
...discovery process from target identification through... ...and dynamic AI/ML scientist with a passion for leveraging... ...antibodies, antigens, ADCs, and other modalities)... ...experimental platforms generating quality data... ...novel tools that enhance therapeutic discovery and development...PlatformTemporary workLocal area- CRISPR Therapeutics in Boston is seeking a highly motivated Scientist II with expertise in lipid nanoparticle design and a strong background in bioconjugation chemistry... ...delivery systems to drive our delivery platform's development. The ideal candidate will possess...Platform
- ...Principal Scientist Our mission at Asimov is to advance humanity's ability to design living systems... ...a mammalian synthetic biology platform––from cells to software––to enable the... ...design and manufacture ofnext-generation therapeutics. We are seeking a Principal Scientist...PlatformPrincipal
- ...OverviewFounded over a decade ago, CRISPR Therapeutics is a leading... ...and proprietary gene-editing platform designed to enable precise,... ...seeking a highly motivated Scientist II to join our LNP team. This is... ...Experience in the space of target delivery or extra-hepatic delivery...Platform
$160k - $190k
...diseases using its proprietary RNA editing platform. Korro is generating a portfolio of... ...Bio is seeking an experienced analytical scientist to join the growing CMC team. You will... ...method development for small molecule therapeutics. Experience in synthetic oligonucleotide...PlatformPrincipalFlexible hours$142.5k - $256.5k
...Principal Scientist, Computational Protein Design page is loaded## Principal Scientist, Computational... ..., binders, and antibodies for mRNA therapeutics, applying state-of-the-art deep... ...to build the leading mRNA technology platform, the infrastructure to reimagine how medicines...PlatformPrincipalPermanent employmentWork at officeWork from home$30.05 - $43.75 per hour
...the world. Position: Medical Technologist II Department: Labs-Hematology Schedule:... ...CLIA '88. May also perform phlebotomy or therapeutic procedures. Job Requirements EDUCATION Requires... ...over text messages or social media platforms. We do not ask individuals to purchase...PlatformFixed term contractInternshipFlexible hoursAfternoon shift$142.5k - $256.5k
...The Role Moderna is seeking a Principal Scientist to support the AI‑enabled design of de novo antibodies... ...function in vivo as part of mRNA therapeutics. The Principal Scientist will work... ...Contribute to cross‑functional program and platform strategy discussions, helping shape...PlatformPrincipalPermanent employment$119.7k - $222.3k
...the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...clinical development, or in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior...PrincipalFull timeLocal area$166.77k - $202.09k
...experienced, creative, and highly collaborative scientist to join our Biotherapeutics Computational... ...portfolio (antibodies, multispecifics, ADCs, and novel scaffolds) and play a pivotal... ...in scaling an agentic antibody design platform from prototype to a core engine of...PlatformPrincipalFull timeTemporary work- ...that need them most. Raven’s experienced scientists, operators, and healthcare innovators have deep sector expertise across therapeutics, diagnostics, devices and services. They... ...innovators a collaborative and comprehensive platform to explore the novel and the re‑imagined....PlatformPrincipal
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