US Senior Medical Director, Rare Hematology

Job title: US Senior Medical Director, Rare Hematology

Location: Cambridge, MA / Morristown, NJ

About the job

Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you'll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.

The US Senior Medical Director (SMD) is a Cambridge/Morristown-based member of the US Medical Affairs team within the Rare Blood Disorders franchise, covering the US geography. The mission of this team is to support the company by functioning as the internal expert in rare hematologic conditions - focusing on recent launch in Immune Thrombocytopenia (ITP), and potentially including warm Autoimmune Hemolytic Anemia (wAIHA), and Sickle Cell Disease (SCD) among other rare blood disorders - and helping Health Care Professionals and Payers optimize patient care and treatment outcomes through evidence-based decisions. This is best accomplished through the generation, interpretation, and communication of accurate clinical and scientific information.

The Senior Medical Director plays a key role in this mission by providing strategic leadership across the rare hematology portfolio and reports to the Head of US Medical Affairs, Rare Blood Disorders.

The Senior Medical Director has a national scope and is responsible for the rare hematology therapeutic area. The Senior Medical Director will establish and maintain collaborative medical and scientific relationships with key external physicians and internal constituencies from multiple functional groups - including, but not limited to, Medical Affairs, Clinical Research, Regulatory, Science, Marketing, Sales, Commercial Operations, and Patient and Product Services - while maintaining full compliance with all relevant company, industry, legal, and regulatory requirements.

We are an innovative global healthcare company, committed to transforming the lives of people with immune challenges, rare diseases and blood disorders, cancers, and neurological disorders. From R&D to sales, our talented teams work together, revolutionizing treatment, continually improving products, understanding unmet needs, and connecting communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

Main Responsibilities

Medical Strategy & Leadership

• Develop U.S. medical objectives and strategies across the rare hematology portfolio, aligned with U.S. commercial goals

• Provide medical input to brand teams regarding strategy, tactics, and development of claims

• Serve as the internal expert for rare hematologic conditions and products, and support the field-based U.S. Medical Affairs team

• Develop strategies for and implement medical advisory boards

• Lead execution of the strategic U.S. investigator-sponsored study program

• Develop U.S. scientific communication and publication strategies

• Partner with the R&D organization to support clinical trials across the rare hematology portfolio

• Lead medical affairs activities in support of the near-term launch of rilzabrutinib (rilza) for ITP, serving as a key strategic and scientific resource during this critical launch phase

• Engage and present to cross-functional leadership and governance forums to advance TA strategy

• Drive preparation for future lifecycle management and upcoming product launches across the rare hematology portfolio, ensuring medical readiness and cross-functional alignment

Field Medical & MSL Direction

• Provide strategic direction to disease-specific MSL teams responsible for translating medical strategy into operational tactics

• Support product and disease-state training of internal colleagues across the rare hematology portfolio

Payer & Access Support

• Support the Managed Markets group, particularly in discussions with payers regarding rare hematology therapies

• Review Educational Outreach Grants to ensure alignment with strategic goals

Compliance & Ethics

• Ensure ethical and credible promotion; potentially sit on Promotional and Medical Review boards

• Ensure full compliance with all corporate and industry policies and legal and regulatory requirements for all Medical Affairs activities

Scientific Excellence

• Maintain medical and scientific knowledge through continuing education, including attending symposia and keeping abreast of current literature across rare hematologic conditions

• Stay updated on emerging scientific, technological, and regulatory developments to inform strategic decision-making

Travel

• Approximately 20% travel expected

About You

Basic Qualifications

• Doctorate degree (PhD, or PharmD). Will consider MD with relevant experience.

• At least 10 years of Medical Affairs experience with strategic and tactical planning and execution

• Experience in rare hematology or a related therapeutic area (ITP, wAIHA, SCD, or adjacent rare blood disorders)

Preferred Qualifications

• Proven success as a strategic thinker and planner

• Superb communication skills - oral and written, including presentation skills

• Outstanding interpersonal skills, including building strong working relationships and managing and resolving conflict

• Well-organized, with demonstrated ability to work effectively in a highly matrixed, cross-functional environment; strongly team-oriented

• Experience in developing, conducting, and publishing peer-reviewed scientific or clinical research

• Additional training or experience in epidemiology, health economics, or health policy and outcomes-based research and practice

• Hard-working, energetic, and passionate about improving outcomes for patients with rare hematologic conditions

• An unwavering commitment to upholding the highest ethical, legal, regulatory, and scientific standards

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

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US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$206,250.00 - $343,750.00

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK ( .

We are an R&D driven, AI-powered biopharma company committed to improving people's lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people's lives.

We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world.

Discover more about us visiting or via our movie We are Sanofi (

Start a career that makes a difference.

Reinvention is in our DNA. It's what drove our evolution from a small French enterprise to one of the world's leading biopharma companies. Whether it's using AI to shorten drug-discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities.

This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people's lives.