Principal Scientist
Genentech
Genentech in South San Francisco seeks a Principal Scientist (Group Leader) to drive oligonucleotide modalities across drug-discovery programs. You will design, synthesize, purify, and characterize ASOs/siRNAs, mentor scientists, and partner with biology teams to enable rapid decision-making. You are a scientific leader with a Ph.D. and 3+ years postdoc/industry experience, fluent in communicating complex concepts and advancing cross-functional initiatives. #J-18808-Ljbffr Genentech
- ...responsible for CMC analytical development of AbbVie's pipeline of innovative therapeutic biologic products. We are a world-class team of scientists and leaders united by a shared mission to advance industry-leading analytical capabilities and meaningfully contribute to the...PrincipalFull timeLocal area
$228.7k - $309.4k
...in foundation models to build an intelligence layer on top of one of the world's largest music and podcast catalogs.As a Principal Applied Scientist, you'll drive innovation in music content understanding, leveraging foundational models to enrich catalog data intelligence...PrincipalTemporary workLocal areaWorldwideFlexible hours$168.6k - $313k
...s what makes us Genentech. The Opportunity We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and development team. This is a technical leadership position within our Peptide Therapeutics...PrincipalLocal areaRelocation package$255.8k - $402.7k
...Job Description The Clinical Director (Principal Scientist) has primary responsibility for the strategic planning and directing clinical research activities involving investigational compounds in Immunology. With a focus on late-stage development, the Clinical Director...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$143.2k - $265.9k
...The Position The Opportunity We are seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join our R&D team. This is a primarily lab-based, technical leadership position within the Peptide Therapeutics department. In this lab-based leadership...PrincipalLocal areaRelocation package- Amgen na nasu mission to serve patients seeks a Principal Scientist to advance the GEM Molecular Validation & Technologies program. This role provides technical leadership in molecular characterization of genetically engineered models, supporting integrity from generation...Principal
- Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages...Principal
- Amgen seeks a highly skilled Principal Scientist to lead GEM molecular characterization and validation. You will advance CRISPR‑based model generation, orthogonal QC, and sequencing workflows, enabling scalable, AI‑driven analysis. The role requires deep experience with...Principal
- IDEAYA Biosciences in South San Francisco is seeking a talented discovery medicinal chemist to lead projects and propose novel molecules that advance oncology programs. You will work in a cross-functional team, design and synthesize drug-like candidates, and push compounds...Principal
$173.1k - $321.5k
The PositionWe advance science so that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy in support of our Cell Therapy portfolio. In this role, the individual will define and drive the...PrincipalFull timeLocal areaRelocation package$143.29k - $266.11k
The PositionThis role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization...PrincipalFull timeLocal areaRelocation package$147.8k - $274.4k
...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative... ...are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group...PrincipalFull timeLocal areaWorldwide$155k - $200k
...biology of epigenetic aging and disease using experiments of unprecedented scale. This Position NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development. In this role, you will lead the discovery...Principal$201.3k - $373.8k
...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative... ...engineering acumen. We're looking for an exceptional Principal Scientist who can architect how our computational models become...PrincipalFull timeLocal areaWorldwide- Client is seeking an experienced and driven scientist/engineer to lead late-stage upstream cell culture process development activities for clinical and commercial-stage large molecule programs. This individual will serve as the upstream lead for scale-up and tech transfer...PrincipalContract work
$194.1k - $305.6k
...Job Description The South San Francisco DMPK organization is seeking an accomplished and highly collaborative Senior Principal Scientist to provide scientific leadership across drug conjugate discovery and development programs, support strategic portfolio decisions,...PrincipalFull timeContract workFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$130.8k - $242.8k
...power of data and Artificial Intelligence (AI) to assist our scientists in delivering more innovative and transformative medicines for... ...postdoctoral research or ≥3 years equivalent experience after PhD (Principal Scientist). The ideal candidate will have deep experience in...PrincipalLocal areaWorldwideRelocation package3 days per week- About the Role Onsite (South San Francisco, CA). Principal Scientist, Potency; reports to Sr. Director, Head of Molecular and Potency Method Development. Responsibilities Develop and qualify pivotal stage potency, immunoassay, and other cell-based methods to support characterization...PrincipalWork at office
$150k - $180k
We are seeking a Senior/Principal Scientist to lead the bioanalytical/analytical characterization of our oligonucleotide therapeutics. The role blends strong mass spectrometry capability with a broader bioanalytical and pharmacokinetic remit: you will develop and apply...PrincipalFull time$180k - $215k
...opportunity to change the cell therapy landscape. Overview Nkarta is seeking a highly motivated, collaborative, detail-oriented Principal Scientist to join our Translational Medicine team. This is a high-impact, hands-on leadership role for a senior bioinformatics...PrincipalFull timeWork at officeFlexible hoursShift work$200k - $240k
...medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Principal Scientist, Potency, you will report to the Sr. Director, Head of Molecular and Potency Method Development. You will either lead or...PrincipalTemporary workWork at officeImmediate startWeekend work$159k - $207k
...consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation and drug product process development lead...PrincipalContract workLocal area$159k - $207k
## Principal Scientist, Commercial & Late-Stage Cell Culture Process DevelopmentApplylocations: South San Franciscotime type: Full timeposted on: Posted 2 Days Agojob requisition id: R-1619Neurodegenerative diseases are one of the largest medical challenges of our time....PrincipalWork experience placementLocal area$92.6k - $172k
...centered parenteral drug products including Formulation and Process Development and Drug Delivery Systems.The OpportunityThe Principal Associate Scientist ensures robust clinical and commercial parenteral drug product process designs for effective process validation and...PrincipalFull timeLocal area$143.2k - $265.9k
The Position The Opportunity SE7 As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our Drug Metabolism and Pharmacokinetics (DMPK) team, you will play a key role in advancing safe and effective therapeutics for patients. Joining Genentech...PrincipalLocal areaRelocation package- ...them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Scientist - GEM Molecular Validation & Technologies What you will do Let’s do this. Let’s change the world. We are seeking an experienced...PrincipalFlexible hours
$143.2k - $265.9k
The PositionTHE OPPORTUNITYThe Department of Immunology Discovery at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation cell therapies to treat autoimmune diseases. The successful...PrincipalFull timeLocal area$209k - $313k
...Engineering, Strategy, and Sales to ensure Snap’s ad products are effective, efficient, and customer‑centric.We’re looking for a Principal Marketing Scientist to join Snap inc.!What You’ll DoSet and influence the measurement strategy for Snap’s third-party (3P) ecosystem,...PrincipalFull timeLive inWork at officeLocal area$120k - $165k
...that behind every test there is a patient waiting.Learn about the Danaher Business System which makes everything possible.Principal Clinical Scientist. This role is responsible for clinical trial strategies within the US and EU regions for Danaher Diagnostics. This role...PrincipalFull timeImmediate startRemote workWork from homeFlexible hours- ...Job Description Job Description Job: Associate Director/Principal Scientist, CMC Analytical Chemistry Location: San Francisco, CA or Thousand Oaks, CA Position type: Full Time Reports to: Director of Analytical Chemistry Organization Overview Latigo...PrincipalFull timeContract workWork at office
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