Director, Nonclinical Toxicology & PK — Biologics Safety Lead
Pinetree Therapeutics, Inc
Pinetree Therapeutics, Inc is seeking a Director or Senior Director of Nonclinical Toxicology & PK to provide scientific leadership across multispecific antibody programs. You will own nonclinical safety, PK, and clinical translation strategies from discovery through IND-enabling development, designing and overseeing GLP studies and CRO collaborations. The ideal candidate is tox-first, biology-driven, with deep experience advancing biologics into the clinic and a track record in regulatory #J-18808-Ljbffr Pinetree Therapeutics, Inc
- Pinetree therapeutics is seeking a Director or Sr. Director of Nonclinical Toxicology & PK to lead integrated nonclinical safety and PK for multispecific antibody programs. This role may be remote or hybrid, with 2-4 onsite days monthly. The candidate should have a PhD,...SuggestedRemote job
- Director / Sr. Director, Nonclinical Toxicology & PK Pinetree therapeutics 25.11.05 Location: Cambridge... ...integrated nonclinical safety, PK, and clinical... ...candidate is a tox-first, biology-driven drug developer with... ...the nonclinical safety lead on cross-functional program...SuggestedFull time
$212k - $333.19k
...group of experienced biologic drug hunters with... ...resources of a leading pharmaceutical company... ...cost, and the safety call is the one that... ...it forward. As Nonclinical Safety Lead, you own... ...risk-proportionate toxicology plan aligned to... ...DMPK to integrate PK/TK, metabolite profiling...SuggestedMinimum wageTemporary workLocal areaImmediate startRemote work$174k - $184.95k
...subsidiary of Bayer AG, is a leading engineered cell... ...the convergence of cell biology and genetic... ...strategic leadership for nonclinical studies in support of... ...leverage their expertise in toxicology to advance the company... ...study design Identify safety-related knowledge gaps...SuggestedLocal areaWorldwide- Beam Therapeutics is seeking an Associate Director/Director of Toxicology to lead nonclinical safety assessments supporting discovery and development programs. You will design and execute safety studies and author nonclinical sections for regulatory filings. This role...Suggested3 days per week1 day per week
$176.2k - $277.3k
...Leader (DPL) to represent Nonclinical Drug Safety (NDS) on discovery research... ...small molecules, peptides, biologics and ADC programs) from Target... ...for defining the GLP toxicology study strategy and execution... ...identification/validation through lead optimization in Infectious...Full timeFor contractorsLocal areaWorldwideFlexible hours$156.9k - $247k
...seeking a curious and collaborative Scientific Associate Director for our growing Translational PK/PD organization. The Translational PK/PD Associate... ...supervision, guiding drug discovery strategy with a focus on biologics, protein therapeutics, and peptides.The Translational...Full timeFor contractorsLocal areaFlexible hours$269k - $291.67k
...The Opportunity The Senior Director Toxicology will support the strategy, design, and execution of nonclinical safety programs to aid in the development... ...closely with Discovery Biology, Bioanalytical and... ...risk‑benefit assessments. Lead the design, oversight, and...Local areaRemote work$170k - $230k
...optimally address disease biology. Our diversified... ...Possible”, we are leading the charge toward... ...to the safety assessment of novel... ...investigative and regulatory toxicology, and have... ...authoring and reviewing nonclinical regulatory... ...tolerability assessment and PK/PD evaluation.Lead...Temporary workSummer workLocal area$170k - $210k
...with serious diseases by unlocking biologically important targets long considered... ...conventional medicines. The company's lead investigational medicine,... ...highly motivated and driven Associate Director, Toxicology to lead nonclinical safety programs across a diverse pipeline...Contract workInterim roleLocal areaShift work$152.6k - $283.4k
...provide global, end to end nonclinical safety leadership across multiple modalities... ...you.Key Responsibilities:• Lead PCS Target Teams to design,... ..., PharmD, or equivalent) in Toxicology, Pharmacology, or related... ..., pharmacologist, study director).• Demonstrated expertise across...Full timeRelocation package- Flagship Pioneering is seeking a DMPK project representative to provide scientific and strategic DMPK guidance across our biologics portfolio. You will lead PK/BA/immunogenicity studies, influence discovery and development strategies, and collaborate with multi-disciplinary...Remote job
$229k - $280k
...strategic decision. Job DescriptionRole SummaryThe Senior Director, Head of Cancer Biology, will report to the Head of U.S. Research and serve as a key... ...site leadership team.Provide cancer biology expertise to lead target identification and validation as well as drug...Full timeTemporary workWork at officeFlexible hours$183k - $290k
Our mission is to make biology easier to engineer. Ginkgo... ...new organisms. Senior Director, Multiomics - Ginkgo... ...GM of Datapoints, and lead a multidisciplinary team... ...applications for DRUG-seq — safety first. Expand our high-... ...safety and predictive toxicology chief among them.Turn...Full timeWork at office$179k - $202k
...has demonstrated encouraging safety and clinical activity across... ...Overview: The Associate Director, Nonclinical Development will serve as a... ...anti-fibrotic therapeutics. Lead the planning, oversight, and... ..., Physiology, Pulmonary Biology, Biochemistry, or a closely...Local area$212k - $333.19k
...true to the best of my knowledge.Job DescriptionSenior Director, AIRx Discovery Biology Lead Takeda Research is constructing the Discovery Automation... ...cycles alongside medicinal/computational chemists, DMPK, safety, and structural biology Challenge scientific assumptions...Minimum wageTemporary workLocal areaRemote work$185k - $260k
...company committed to establishing the leading, fully integrated platform for... ...highly talented and motivated Associate Director / Director, Toxicology to join our growing Non-Clinical... ...Toxicology will be responsible for the nonclinical safety assessments supporting Beam's...Full time3 days per week1 day per week- OverviewThe Associate Director, Nonclinical Writing Innovation, will lead the strategy and adoption of AI-enabled capabilities across nonclinical workflows. This high-visibility role will translate organizational priorities into scalable digital solutions that improve productivity...Full timeContract workTemporary workLocal areaFlexible hours
$166.4k - $249.6k
...DescriptionGeneral Summary:The Chemistry Manufacturing Controls (CMC) Associate Director leads and executes global regulatory CMC strategies across investigational and commercial products focusing on biologics. This role is accountable for authoring, reviewing, and delivering...Full timeSummer workRemote workFlexible hours2 days per week- ...Senior Director, AIRx Discovery Biology Lead Responsibilities / Accountabilities Own disease biology and target validation strategy across the... ...cycles with medicinal/computational chemists, DMPK, safety, and structural biology. Challenge scientific assumptions...
- Responsibilities: Design, execute, and interpret nonclinical safety studies across all phases of drug development, including GLP toxicology, reproductive toxicology, carcinogenicity, and safety pharmacology. Use pharmacokinetic data to justify toxicology study doses and...
$176.1k - $287.3k
Associate Director of Pathology has primary responsibility... ...efficacy and safety studies in a variety... ...Pathology support for GLP toxicology and PK studies of Regeneron... ...leader supporting nonclinical drug development across... ...have Regeneron is a leading biotechnology company...$94.6k - $141.8k
...DescriptionGeneral Summary:The Associate Director, GMP Operational Quality... ...complex programs. This role leads day-to-day quality operations... ...decisions align with patient safety, product quality, regulatory... ...a key member of the Vertex Biologics and Devices Quality Team,...Full timeContract workSummer workRemote workFlexible hours2 days per week$100k - $250k
Nonclinical Safety & Pharmacokinetics, Director, Contract, Onsite Contract Director, Developability and Early CMC Development... ..., ADC or protein/antibody fusion lead screening and further development... ...with Discovery, Molecular Biology, and Translational Research teams...Full timeContract workImmediate start- Director of Nonclinical Safety, Cambridge, MA Cambridge, MA Isomorphic Labs is applying... ...symmetry between biology and information science. By... ...diseases. We have built a world-leading drug design engine... ...MAA-enabling) nonclinical toxicology work, including chronic, reproductive...Work at office3 days per week
$181k - $192.06k
...independently operated subsidiary of Bayer AG, is a leading engineered cell therapy company... ...forefront of the convergence of cell biology and genetic engineering. Our mission is... ...across multiple disease areas. The Associate Director, TMND, will be expected to take on a...WorldwideShift work$160k - $240k
Job DescriptionGeneral Summary:The Associate Director, Technical Services is accountable for the technical execution of biologics drug substance manufacturing at external... ...manufacturingDemonstrated experience supporting or leading manufacturing execution at a site or...Full timeSummer workRemote workFlexible hoursShift work2 days per week$174k - $196k
Associate Director, Clinical Pharmacology Cambridge, Massachusetts... ...deep expertise in RNA biology, we are building a... ...for pharmacokinetic (PK), pharmacodynamic (PD),... ...Key Responsibilities Lead development and... ...submissions. Integrate nonclinical, translational, biomarker...Work at officeWork from homeFlexible hours$240k - $389.4k
...Senior/Executive Director [commensurate with... ...for the medical and safety leadership for all... ...plans.Workswith toxicology and pharmacokinetics... ...emerging human PK/PD data to inform... ...asset and disease biology) and applying this... ...and ADME functional leads and, as part of the...Local areaRemote workFlexible hours$177k - $278.08k
...capabilities into Takeda’s nonclinical research workflows... ...of efficacy and safety assessment... ...Pathologist and/or Project Toxicology representative on... ...into development.Lead pathology... ...pathology, computational biology, or translational... ...consistent with a Director-level roleTakeda...Minimum wageLocal area
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