Principal Scientist - Clinical Research, Immunology Biomarker Lead
$190.8k - $300.3kMerck
Principal Scientist position leading immunology biomarker strategy across clinical development programs. The role combines scientific expertise with cross-functional leadership to design and execute biomarker strategies that inform clinical decisions and support precision medicine approaches in immunology.
Responsibilities
- Lead integrated biomarker strategies across discovery and clinical programs, connecting drug mechanism to clinical endpoints
- Serve as biomarker strategy lead for cross-functional program teams and represent them in governance forums
- Direct biomarker sub-teams and working groups spanning clinical, discovery, translational, regulatory, and data sciences
- Champion analysis plans and provide scientific interpretation of complex datasets for clinical conclusions
- Support external engagement including publications, presentations, and key opinion leader interactions
Requirements
- PhD or MD in Immunology, Biology, or related STEM field with 7+ years immunology experience
- Deep expertise in immune-mediated diseases, particularly rheumatology, GI/mucosal inflammation, or dermatology
- Proven track record translating biomarker strategies into clinical development decisions
- Demonstrated ability to lead highly matrixed teams and influence cross-functional stakeholders
- Working knowledge of biostatistics, bioinformatics, and advanced data analytics
- Strong analytical and problem-solving skills with ability to synthesize complex data into actionable insights
- Experience advancing precision medicine and personalized medicine strategies
Vacancy posted 22 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist - Clinical Research, Immunology Biomarker Lead in West Point, PA vacancy
$142.4k - $224.1k
...Merck seeks an Associate Principal Scientist to lead clinical operations for early-phase immunology trials, spanning Phase 1 and 1b studies. The role involves designing clinical strategies, managing cross-functional teams, ensuring regulatory compliance, and authoring...Principal- Johnson & Johnson's Biologics Discovery seeks a Principal Scientist and Team Lead in Protein Purification. The role focuses on advancing therapeutic antibodies, multispecifics, and recombinant proteins for preclinical studies. You will lead a team, define purification strategies...Principal
- ...Title): Associate Principal Scientist Department... ...Translational Medicine, Clinical Operations Brief... ...-Stage Clinical Research to translate... ...the execution of Immunology programs including... ..., novel endpoint/biomarker collection processes... ...development teams. Leads the development...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work
- Role Principal Scientist and Team Lead in Protein Purification within Johnson & Johnson's Biologics Discovery, focusing on advancing therapeutic antibodies, multispecifics, and recombinant proteins for preclinical studies. Responsibilities Responsibilities include building...Principal
- Role Principal Scientist in High-Content Imaging within Johnson & Johnson's Innovative Medicine division, focusing on advancing therapeutic discovery in Immunology, Neuroscience, and Oncology. Responsibilities include developing, validating, and deploying complex high-...Principal
$231.9k - $365k
...Merck's Research Laboratories seeks an experienced veterinary pathologist to lead nonclinical drug safety assessments for oncology, immunology, vaccines, and biologics candidates. The role emphasizes... ...Contribute to developing novel biomarkers and predictive models to de-...Principal$117k - $201.25k
...Job Function Discovery & Pre-Clinical/Clinical Development Job... ...Clinical Pharmacology (CP) Principal Scientist . Purpose The Clinical Pharmacology... ..., safety), PK, PD (e.g., biomarker, efficacy, and/or safety),... ..., Report Writing, Researching, Research Proposals, Scientific...PrincipalLocal areaImmediate start$137k - $235.75k
...Function Discovery & Pre-Clinical/Clinical Development... ...& Development Biomarkers Job Category Scientific... ...Manager, Global Diagnostic Lead, Oncology Precision Medicine... ...with Translational Research, Clinical Development,... ..., genetics, immunology, pathology, biomedical...Contract workLocal area- ...Oncology Statistics team seeks a Senior Principal Statistician to provide strategic... ...oncology drug discovery programs in the US. Lead statistical strategy, apply advanced modeling, AI/ML, and biomarker analytics to accelerate research. You will design experiments, analyze...Principal
- ...treatments and cures. We lead where medicine is... ...the Oncology Discovery Scientist role, you will be a member... ...team dedicated to the research and development of new... ...process and clinical research Data collection... ...biochemistry, genetics, immunology/immuno-oncology, computational...Full timeInternshipSummer internshipH1bLocal areaRemote work
$282.2k
...Senior Principal Scientist position leading clinical research strategy and execution for oncology drugs across all development phases. Responsible for study design, trial management, regulatory submissions, and cross-functional collaboration within a global healthcare...Principal$255.8k - $402.7k
...Principal Scientist role overseeing clinical research activities for oncology medicines across all development phases. Responsibilities include study design, trial management, regulatory reporting, and cross-functional collaboration to advance new and marketed drugs through...Principal$190.8k - $300.3k
...Senior Principal Scientist leading nonclinical drug safety strategy for immunology programs at Merck. Responsible for overseeing development progression, regulatory submissions... ...and regulatory submissions supporting global clinical development and registration Provide...Principal$282.2k
...Senior Principal Scientist position in breast cancer clinical research at a pharmaceutical company. Responsibilities include developing clinical trial strategies, evaluating preclinical data, managing ongoing studies, and collaborating across functional teams to advance...Principal- Role Associate Director Clinical Scientist providing scientific leadership across multiple clinical studies... ...and drug development expertise; experience in immunology preferred. High-Value focus on autoimmune diseases, biomarker and efficacy data interpretation, and...
$156.9k - $247k
...Description We are a research-driven biopharmaceutical company... ...opportunity for a new Associate Principal Scientist to join our Oncology health... ...and use of industry-leading predictive and economic models... ...discovery, real world evidence, clinical trial and published data,...PrincipalFull timeFor contractorsWork experience placementWork at officeLocal areaFlexible hoursMSD
West Point, PA2 days ago- Johnson & Johnson Innovative Medicine is seeking a Senior Principal Scientist, CMC Regulatory Affairs - Combination Products. This hybrid role... ...; Titusville, NJ; Spring House, PA; or Horsham, PA. You will lead complex regulatory strategies for drug-device combinations, mentor...Principal
- Merck & Co., Inc. in the United States is seeking an Associate Principal Scientist to advance biologics pipeline programs. You will lead process characterization, scale-up, transfer and process validation activities to support late-stage and commercial products. The role...Principal
- Johnson & Johnson is seeking a Clinical Pharmacology (CP) Principal Scientist to lead PK/PD analyses, PK/PD modeling, and MIDD applications across development programs. You will author CP sections for regulatory submissions and influence study designs in collaboration...Principal
- Scorpion Therapeutics is seeking a Lead statistician to oversee safety analyses in Oncology programs as part of the CSS group, providing scientific expertise and strategic oversight for safety analyses throughout the product lifecycle. You will partner with cross‑functional...Principal
- Johnson & Johnson in Spring House, PA is seeking a Principal Scientist, High-Content Imaging, to advance therapeutic discovery across Immunology, Neuroscience, and Oncology. You will design and execute end-to-end imaging workflows in 2D/3D models, develop novel molecular...Principal
- Role Principal Scientist, Biostatistics at Johnson & Johnson's Innovative Medicine division, providing... ...expert statistical input across research, clinical development, and manufacturing... ...regulatory submissions optimize trial designs lead methodological advancements...PrincipalRemote work
- Role: Lead statistical safety evaluation within the CSS group for Oncology Therapeutic Area programs, providing scientific expertise... ...software (SAS/R); knowledge of regulatory safety requirements, clinical trial design, and real-world data analysis. Preferred: knowledge...Principal
$82k - $92k
Postdoctoral Research Fellow - Vaccine Preclinical Development... ...in virology, immunology, computational biology... ...successful candidate will lead independent and... ...frameworks leading to biomarker discovery Present findings... ...analysis of clinical cohort datasets Why Join...For contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- Role: Senior Scientist, Global Labeling Lead, responsible for developing and maintaining compliant labeling content for development and marketed biopharma products, including Core, US, and EU Labeling. Objectives: ensure high-quality, regulatory-compliant labeling documents...
- Role Principal Scientist, CMC Regulatory Affairs - Combination Products, providing regulatory expertise for drug-device combination products... ...components. Responsibilities Developing regulatory strategies for clinical, marketing, and lifecycle activities; Preparing submission...Principal
$137k - $235.75k
...Job Function Discovery & Pre-Clinical/Clinical Development Job... ...is recruiting for a Senior Principal Scientist, CMC Regulatory Affairs - Combination... ...expert responsible for leading complex combination product... ...Regulatory Environment, Scientific Research, Strategic Thinking, Subject...PrincipalLocal areaImmediate start- Johnson Service Group, Inc. is seeking a Senior Chemist for a lab-based role in West Point, PA. This on-site position involves routine pharmaceutical testing including stability assays and may involve method validation. Strong HPLC and GMP experience are required. BS in...
- ...Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: Scientific/... ...searching for the best talent for a Principal Scientist, High-Content Imaging role... ...discovery across the Immunology, Neuroscience, and Oncology...PrincipalLocal area
- Johnson & Johnson's Innovative Medicine division seeks a Principal Scientist in High-Content Imaging based in Spring House, PA. You will lead the development and deployment of complex imaging assays across immunology, neuroscience, and oncology programs, driving technical...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist - Clinical Research, Immunology Biomarker Lead. Be the first to apply!
Related searches
- drug safety scientist West Point, PA
- materials scientist West Point, PA
- senior scientist West Point, PA
- scientist biology West Point, PA
- manufacturing scientist West Point, PA
- cell culture scientist West Point, PA
- water quality scientist West Point, PA
- lab scientist West Point, PA
- research scientist West Point, PA
- deep learning scientist West Point, PA