USA - Bench Scientist - II - USD (contract)

Location: Cambridge, MA, United States (On-site) Contract (1 year 11 months 15 days) Published 9 days ago On hold Skills: LIMS, DNA production, Automation, Scripting, Biotage system, nanoparticles, QC Testing Overview Pfizer’s BioMedicine Design (BMD) organization is seeking a highly motivated Biochemist/Molecular Biologist to join the Biotherapeutic Expression and Purification (BEP) group in Cambridge, MA. This position plays a critical role in a fast‑paced DNA production and protein expression research laboratory. The BEP team supports non‑GMP transient protein lead production across Pfizer's diverse biotherapeutics discovery portfolio, enabling research and preclinical in vitro and in vivo studies across multiple therapeutic areas. Key Responsibilities DNA Production & Molecular Biology : Independently execute high-throughput plasmid DNA production workflows, including bacterial culture growth, plasmid purification, and large‑scale DNA production using standardized protocols. Manage plasmid DNA inventory, storage, and tracking within electronic databases and sample management systems. Automation & Laboratory Operations : Operate, maintain, and troubleshoot automated instrumentation such as Biotage systems and related liquid‑handling technologies. Support high-throughput laboratory operations while maintaining quality and efficiency. Quality Control & Sequencing Support : Conduct DNA quality control testing—nucleic acid quantification, purity assessment, endotoxin testing—and prepare and submit samples for next‑generation sequencing (NGS). Assist with basic review and interpretation of sequencing results. Documentation & Compliance : Maintain accurate and complete records in electronic laboratory notebooks (ELNs) and ensure documentation complies with laboratory and organizational standards. Adhere to laboratory safety requirements and regulatory guidelines. Partner with expression and purification scientists to ensure timely DNA delivery for downstream applications. Identify and implement process improvements to enhance throughput, reproducibility, and operational efficiency. Communicate project status, priorities, and potential risks to support production timelines and deadlines. Qualifications Bachelor's degree (B.S.) in biological sciences, molecular biology, biotechnology, biochemistry, or related field. 2+ years of experience with molecular biology techniques, including plasmid preparation, nucleic acid purification, quantitative DNA analysis. Proficiency in DNA quality control methods, including gel electrophoresis and sequencing sample preparation. Experience operating automated or semi‑automated laboratory instrumentation. Strong organizational skills with the ability to manage multiple projects in a high-throughput environment. Experience using electronic laboratory notebooks (ELNs) and sample tracking systems. High attention to detail, particularly when performing repetitive, high-volume tasks. Strong communication, collaboration, and teamwork skills. Commitment to laboratory safety, quality, and compliance. Preferred Qualifications Experience with next‑generation sequencing (NGS) library preparation and sequencing workflows. Familiarity with Python scripting for data analysis or laboratory workflow automation. Experience working with 96‑well and/or 384‑well high-throughput plate-based workflows. Familiarity with Laboratory Information Management Systems (LIMS) and sample management platforms such as Genedata. Pay Rate Range Hourly: $38 - $43 USD Benefits Information Comprehensive Benefits Package available based on eligibility Short‑Term Disability (STD) Long‑Term Disability (LTD) Supplemental and Voluntary Life Insurance #J-18808-Ljbffr Pfizer