Director, Global Health Economics Lead, Oncology Business Unit

Job Description About the role: As a member of Takeda Oncology, your work will contribute to our bold, inspiring vision: We aspire to cure cancer. Here, you'll build a career grounded in purpose and be empowered to deliver your best. As part of the Global Health Economics team, you will report to the Head of Global Health Economics and US HEOR. Drive and realize value demonstration strategies for Takeda’s global oncology portfolio, achieving rapid, broad patient access and delivering differentiated, evidence-based pricing through best-in‑class health technology assessment (HTA; including the EU Joint Clinical Assessment [JCA]) and payer decision outcomes. Lead cross‑functional integration and impact, resulting in accelerated market access, measurable commercial performance, and sustainable advantage across various assets and indications worldwide. Lead the strategic development, execution, and continuous optimization of global health economics (HE) plans, reimbursement strategy, and evidence communication. Build and deploy best‑practice tools and training to maximize adoption and impact of global HE deliverables across all regions. Mobilize and align cross‑functional and cross‑regional stakeholders at all enterprise levels, including R&D, Market Access, and local operating companies (LOC), to ensure seamless integration of evidence requirements and accelerate value realization for patients and payers. Co‑lead the vision, development, and adaptive evolution of enterprise‑level frameworks (e.g., Integrated Evidence Generation Plans [EGPs]), ensuring that all evidence and access strategies are fully aligned with evolving payer, HTA, and policy needs globally. Pioneer and implement innovative digital, data science, and AI‑driven health economics and outcomes research (HEOR) approaches, actively shaping Takeda’s future market access strategy. Influence enterprise‑level decision‑making and mentor emerging leaders through formal educational and strategic thought leadership programs. Advance Takeda’s global reputation and influence by proactively shaping thought leadership at international and industry forums, policy discussions, and leading scientific consortia—building strong partnerships with HTA, payer, academic and clinical stakeholders, and elevating Takeda’s position as a recognized leader in HE and value demonstration. How you will contribute: Global Value Proposition: Drive and deliver differentiated, evidence‑based global HE value propositions resulting in best‑in‑class HTA/payer decisions, accelerated market access, and sustainable competitive advantage across the oncology portfolio. Anticipate and capitalize on emerging payer and societal needs. Direct and oversee the co‑development with Global Pricing, Value & Access (PVA) and cross‑functional leaders to build compelling, evolving value narratives that impact payer decisions and drive optimal patient access worldwide. Drive strategic identification and prioritization of high‑value opportunities—including new indications, lifecycle extensions, and innovative contracting models—across the portfolio. Evidence Generation: Provide enterprise‑wide vision and impactful leadership in evidence generation to secure HTA, payer, and market access objectives, integrating payer and real‑world data needs across global, regional, and local programs. Pioneer new approaches, including digital, data science, and AI, to transform evidence generation and proactively shape Takeda’s response to dynamic global value trends. Review recommendations for advanced evidence needs (e.g., RWE, patient‑centered outcomes), ensuring that internal and external partners are aligned to address emerging payer trends and requirements. Lead the incorporation of innovative and payer‑relevant endpoints in clinical development strategies and ensure robust HTA (including JCA) readiness. HE and Value & Access Tools: Set enterprise‑wide benchmarks for scientific rigor in HEOR studies; ensure continuous innovation, external credibility, and differentiation with HTA bodies and payers. Drive the implementation of global HE strategies and tools (Value Platforms, Dossiers, value‑based contract (VBC) toolkits) and ensure consistent capability build across regions and LOCs, directly spearheading global rollouts and advanced training programs. Co‑lead the conceptualization and execution of VBC options in collaboration with Market Access and Pricing, assessing and advancing their commercial impact. Continuously advance all HE and Market Access tools in response to dynamic evidence and payer environments. Market Access: Serve as enterprise expert and spokesperson for Takeda’s global product value proposition—proactively engaging, influencing, and shaping both HTA policy and payer decisions to safeguard and expand market access opportunities. Monitor and anticipate trends in the global HTA/reimbursement landscape to guide, shape, and transform Takeda’s HE and access strategies at the enterprise level. Communication/Publication: Elevate Takeda’s visibility and reputation through global HEOR communications, policy publications, and leading contributions to industry discourse. Lead global communication strategy, translating complex technical analyses into actionable, compelling value stories for executive, payer, and policymaker audiences. Foster Superior Collaboration: Mobilize, empower, and align cross‑functional and external networks to deliver enterprise‑wide HEOR and Market Access innovation. Facilitate global knowledge sharing, mentoring, and continuous capability‑building. Cultivate and manage advanced collaborations with HE opinion leaders, vendors, and academic partners to ensure Takeda remains at the forefront of innovation and excellence in health economics. Basic Qualifications/Requirements: Doctorate with 7+ years of experience, Master's with 9+ years of experience or Bachelor's with 12+ years of experience in healthcare industry with direct experience in global product value proposition development (industry or consulting) and interaction with payers, HTA bodies, relevant policymakers and strong patient‑centered focus. Robust understanding of the global payer environment and in‑depth understanding of ex‑US payer landscape including HTA trends and guidance (e.g., NICE, CADTH, PBAC, EU JCA), along with knowledge of US Medicare (Part D), ICER in the US and trends in Emerging Markets (e.g., China) – including reimbursement methodologies, pricing/reimbursement authorities’ decision‑making process and current reimbursement issues. Strong knowledge and hands‑on experience in health economics, health technology assessment (HTA) tools, methods and filings, SLRs, ITCs, statistical analyses and economic modelling. Strong knowledge and understanding of clinical and epidemiological information, innovative global pricing models, all phases of drug development methods of analysis of large databases (e.g., claims data, electronic health records) and the major areas of Outcomes Research (PROs, modelling). Leadership – strong ability to work in a highly matrixed organization. Strong analytical capabilities and excellent communication skills (written and oral). Strategic thinking and demonstrated problem‑solving capability. Influencing skills (one‑on‑one and in group setting) – consensus builder with ability to effectively drive decision‑making. Ability to translate technical issues to non‑technical experts. 5 to 10% Domestic and/or International travel may be required.

PREFERRED QUALIFICATIONS:

Previous experience in Hematology and/or Oncology. A combination of in‑depth knowledge of Global HTA (including EU JCA) requirements and direct experience in HTA submissions. Direct payer experience and/or experience in Market Access. Track record of peer‑reviewed publications. Locations Boston, MA This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary For Location: Boston, MA U.S. Base Salary Range: $177,000.00 - $278,080.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short‑term and/or long‑term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short‑term and long‑term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well‑being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. #J-18808-Ljbffr Initial Therapeutics, Inc.