Research Associate, Clinical Virology

Research Associate, Clinical Virology

We are seeking a creative and highly motivated Research Associate to join our Clinical Virology team at our South San Francisco location. You will work closely with members of the clinical virology team to support antiviral drug discovery and development.

Specific responsibilities include, but are not limited to:

• Performing testing of clinical isolates to assess viral replication, fitness, and drug susceptibility
• Designing and executing in vitro resistance selection experiments
• Characterizing resistance-associated substitutions through both phenotypic and genotypic analyses
• Generating and evaluating recombinant viruses carrying clinically relevant mutations
• Performing viral propagation, titration, infectivity, and replication assays
• Conducting nucleic acid extraction, qPCR, RT-qPCR, and related molecular assays
• Collaborating with senior research members and cross-functional teams to analyze data, interpret results, and prepare technical reports and study summaries
• Effectively supporting multiple projects and learning new techniques to support novel exploratory discovery work, as needed
• Utilizing data analysis software and MS Office applications
• Participating in general lab maintenance including reagent preparation, ordering of general lab supplies, and maintenance of equipment

This job description outlines the primary duties and responsibilities of the role; however, it is not intended to be all-inclusive. The scope of responsibilities may be modified, expanded, or adjusted at the discretion of the organization to meet evolving business needs.

Qualifications Include:

• Sc./M.S. or equivalent degree in Virology, Molecular Biology, Cell Biology, or relevant scientific discipline
• Minimum of 2 - 5 years of relevant experience in industrial or academic settings, preference given to experience in biomarker and translational research activities.
• Strong expertise in assay development, virology, cell biology, and molecular biology techniques, e.g. viral stock preparation, titration, and replication assays; in vitro resistance selection; (RT)-PCR, (RT)qPCR; Sanger sequencing and NGS; molecular cloning and mutagenesis; data analysis and visualization; etc.
• Must be comfortable working in a BSL2 setting with potentially infectious agents
• Demonstrated expertise in ensuring good laboratory practices and BSL2 standards
• Ability to present experimental rationale and data to other scientists
• Motivated, and proactive molecular virologist and/or cell biologist with desire to work in a fast-paced, dynamic environment

• Familiarity with Microsoft Office applications, GraphPad Prism, molecular cloning programs, and scientific informatics tools for data input, analysis, and management

Pay Range: $87,000 - $91,260 annualized

The stated pay range for this position reflects the San Francisco Bay Area job market. Assembly Bio establishes pay ranges based on geographic work locations. Additional factors such as academic credentials and relevant experience will influence the actual salary offered.

About Assembly Bio

Assembly Bio (NASDAQ: ASMB) is an ambitious biopharmaceutical company with cutting-edge therapeutic candidates capable of improving the lives of millions living with devastating viral and liver diseases. We have multiple ongoing clinical programs focused on the development of novel treatments for herpesviruses, hepatitis delta virus (HDV), cholestatic liver diseases and hepatitis B virus (HBV). Further, our research organization is dedicated to the discovery of new therapies to change the treatment paradigm for individuals living with serious viral and liver diseases.

We pride ourselves on creating a culture and work environment that is scientifically driven, ambitious, and collaborative. We encourage diversity of thought that leads to great innovation and are looking to add great people to our dynamic team who are driven to transform the lives of patients. We set our sights highand pursue our goals with determination. Our unique organization stands ready to welcome talented, motivated individuals, who share our ambitions.

As an equal opportunity employer, we are committed to diversity and inclusion and will not tolerate discrimination and harassment of any kind. All employment decisions are based on business needs, job requirements and individual qualifications, without regard to race, color, religion or belief, national, social or ethnic origin, sex (including pregnancy), age, physical, mental or sensory disability, HIV status, sexual orientation, gender identity and/or expression, marital, civil union or domestic partnership status, past or present military service, family medical history or genetic information, family or parental status, or any other status protected by the laws or regulations in the locations where we operate.