Principal Scientist, Translational Science Program Lead, Immunology
$117k - $195.13kJohnson & Johnson
Principal Scientist leading translational science strategy for immunology programs from discovery through clinical development. This role owns end-to-end translational planning, biomarker strategy, and cross-functional execution for assigned therapeutic assets at Johnson & Johnson.
Responsibilities
- Develop and maintain integrated translational plans connecting disease biology, mechanism, biomarkers, and clinical endpoints
- Lead precision medicine strategy including patient stratification, biomarker endpoints, and target product profile development
- Anticipate program inflection points and define critical evidence requirements, decision criteria, and risk mitigation
- Represent translational science across discovery and clinical teams, aligning partners around integrated recommendations
- Interpret preclinical and clinical data to generate actionable insights and communicate findings to governance bodies
Requirements
- Deep expertise in immunology and translational medicine
- Proven ability to develop integrated translational strategies and stage-appropriate evidence plans
- Strong proficiency analyzing multidimensional biomarker data and high-dimensional datasets
- Experience leading in matrixed environments and influencing cross-functional teams
- Track record translating disease biology and therapeutic mechanisms into clinical development decisions
- Demonstrated scientific credibility and external collaboration experience
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist, Translational Science Program Lead, Immunology in Spring House, PA vacancy
$231.9k - $365k
...pipeline of oncology, immunology, vaccines, biologics,... ...team of scientists (12 anatomic pathologists... ...works with multiple program development teams. Key... ...safety pharmacology, and translational teams to define mechanisms... ...:An industry-leading suite of on-site in vitro...PrincipalFull timeFor contractorsLocal areaMerck Sharp & Dohme (MSD)
West Point, PA6 days ago$255.8k - $402.7k
...opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early... ...Working with basic science teams on specific... ...strategyTaking a lead role in developing... ...pharmacology studies for programs in all phases (I -...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
West Point, PA3 days ago$137k - $235.75k
...patients, whose insights fuel our science-based advancements.... ...more at Purpose: The Senior Principal Scientist will be a key member of... ...Scientist, Preclinical Safety & Translational Sciences-Translational... ...Pharmacology, Pharmacometrics, Program Management, Report Writing,...PrincipalLocal area- ...Merck seeks a physician-scientist to lead translational medicine and early clinical development for neuroscience therapeutics. The role bridges discovery... ...support for neurologic and psychiatric disease programs. Responsibilities Collaborate with discovery teams...Principal
Merck
West Point, PA4 days ago - Role Principal Scientist in High-Content Imaging within Johnson & Johnson'... ...advancing therapeutic discovery in Immunology, Neuroscience, and Oncology... ...analysis pipelines, and translate imaging readouts into... ...collaborations, data integration, and programming in R/Python; familiarity...Principal
- ...Principal Scientist position leading immunology biomarker strategy across clinical development programs. The role combines scientific expertise with cross-functional... ...spanning clinical, discovery, translational, regulatory, and data sciences Champion analysis plans and...Principal
Merck
West Point, PA6 days ago $190.8k - $300.3k
...accomplished and highly motivated Principal Scientist (Director) to serve as an Immunology Biomarker Lead within Translational Clinical Biomarkers. This... ..., directly informing program- and portfolio-level... ...regulatory, bio-stats, and data sciences.Collaborate effectively...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
West Point, PA4 days ago$255.8k - $402.7k
...opportunity for a physician-scientist to join our group as a- Principal Scientist (Clinical Director) in Translational Medicine/Early... ...Working with basic science teams on specific... ...strategy Taking a lead role in developing... ...pharmacology studies for programs in all phases (I -...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$255.8k - $402.7k
...opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early... ...Working with basic science teams on specific... ...strategy Taking a lead role in developing... ...studies for programs in all phases (I -...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$117k - $201.25k
...Analytics & Computational Sciences Job Sub Function... ...is recruiting for a Principal Scientist, R&D Data, Data Science... ...(DDSAI) - Immunology . This position will... ...portfolio. This role helps translate emerging capabilities... ...performance-based compensation programs. Under current...PrincipalTemporary workLocal areaRemote work$117k - $201.25k
...& Computational Sciences Job Sub Function... ...recruiting for a Principal Scientist, AI & Autonomous... ...therapeutic programs. The primary location... ...disorders, immunology, neuroscience, and... ...drug discovery and translational research that... ...pharmaceutical industry. Lead cross-functional...PrincipalTemporary workLocal areaRemote work- ...patients whose insights fuel our science-based advancements. Visionaries like... ...for the best talent for Principal Scientist Protein Purification Team Lead in Spring House PA. Purpose:... ...biological activity manufacturability and program strategy. You will set direction...PrincipalFull timeLocal area
Johnson & Johnson
Spring House, PA11 days ago - ...Johnson Biologics Discovery in Spring House, PA seeks a Principal Scientist, Protein Purification, Team Lead to guide a team delivering purified antibodies,... ...across discovery and development to align strategy with program goals while building an inclusive, high-performance...Principal
- Merck seeks a Principal Scientist (Director) to lead Immunology Biomarker strategies within Translational Clinical Biomarkers. You will shape biomarker strategies bridging biology... ...and clinical endpoints across development programs, guiding decision-making in a fast-paced...
$260.3k - $409.7k
Job Description Translational Medicine is responsible for... ...with Discovery Sciences and late-stage Clinical... ...related conditions. The Principal Scientist (Clinical Director) must... ...for novel therapy programs from Preclinical Candidate... ...biomarker plans for Lead Optimization programs...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- MSD Malaysia is seeking a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development for the Neuroscience therapeutic area in the... ...track record. The successful candidate will lead cross‑functional early development activities, design...Principal
$173.2k - $272.6k
...Merck seeks a Principal Scientist to lead biomarker strategy development across neuroscience drug development programs. The role involves designing translational and clinical biomarker approaches that inform clinical decisions from early through late-stage development,...Principal$190.8k - $300.3k
...Senior Principal Scientist leading nonclinical drug safety strategy for immunology programs at Merck. Responsible for overseeing development progression, regulatory submissions... ...with discovery, regulatory affairs, translational medicine, and clinical development...Principal$260.3k - $409.7k
...Leadership position in translational medicine focused on cardiovascular therapeutic development... ...research teams. Responsibilities Lead early clinical development strategy design... ...for novel cardiovascular therapy programs Develop and execute biomarker strategies...Principal$142.4k - $224.1k
...Associate Principal Scientist role overseeing submission data... ...clinical development programs. Responsibilities... ...Enterprise tool usage Lead SDTM version-up... ...BA/BS in Computer Science, Statistics, Applied... ...thinking capability translating standards into practical...PrincipalWorldwide- Johnson & Johnson Biologics Discovery in Spring House, PA seeks a Principal Scientist, Protein Purification, Team Lead to guide a multidisciplinary group delivering purified antibodies, multispecifics, and other biologics for preclinical studies. You will set purification...Principal
- Role Principal Scientist and Team Lead in Protein Purification within Johnson & Johnson's Biologics Discovery, focusing on advancing therapeutic antibodies, multispecifics, and recombinant proteins for preclinical studies. Responsibilities Responsibilities include building...Principal
$173.2k - $272.6k
Job Description The Director (Principal Scientist), Global Regulatory Liaison... ...projects within the Immunology Therapeutic Area. The individual... ...and who can manage complex programs that may involve multiple indications... ...as the Global Regulatory Lead to Product Development Teams...PrincipalFor contractorsLocal areaRemote workWorldwideRelocationVisa sponsorshipFlexible hoursShift work$190.8k - $300.3k
...Area Leader for Immunology, overseeing the progression... ...development programs and post-... ...Compound Leaders, and scientists across NDS and/or... ...affairs, translational medicine, clinical... ...risk assessments, science-based waiver strategies... ...and proactively lead internal cross-departmental...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
West Point, PA4 days ago$173.2k - $272.6k
...and collaborative scientist for the Drug Metabolism... ...(DMPK) group. The Principal Scientist will be... ...They will assess program risks including DDI, metabolism and translation to guide clinical... ...in Pharmaceutical Sciences, Pharmacology,... ...working as a DMPK lead on discovery teams...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
West Point, PA3 days ago$173.2k - $272.6k
...Merck seeks a Principal Scientist in Drug Metabolism and Pharmacokinetics... ...biologics, assessing program risks, authoring... ..., and clinical translation for development teams... ...PhD in pharmaceutical sciences, pharmacology,... ...DDI strategy ~ DMPK lead experience advancing...PrincipalMerck
West Point, PA10 days ago$282.2k
...Merck seeks a Senior Principal Scientist to lead clinical development strategy and execution for investigational immunology compounds. The role encompasses late-stage trial management... ...Evaluate preclinical and translational data to develop early clinical plans and...Principal$173.2k - $272.6k
...Principal Scientist position in regulatory affairs for immunology programs at Merck, responsible for developing global regulatory strategies and serving as the primary... ...regulatory approvals Serve as global regulatory lead and single point-of-contact for assigned...PrincipalWorldwide$142.4k - $224.1k
...Job Description Translational Medicine (TMed) drives early... ...with Discovery Sciences and Late-Stage Clinical... ...The Early Clinical Scientist (ECS) provides operational... ...phase clinical trials and programs in collaboration with... ...development teams. May lead development of departmental...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$71.9k - $113.2k
Job DescriptionAssociate Scientist, Process Analytics Lab Lead, Biologics Drug Substance CommercializationJoin... ...operations. You will engage our program team members to understand their needs... ...Guideline: B.S in Analytical Sciences/ Chemistry/ Chemical Engineering/ Biochemistry...Full timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
West Point, PA3 days ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist, Translational Science Program Lead, Immunology. Be the first to apply!
Related searches
- support scientist Spring House, PA
- decision scientist Spring House, PA
- scientist Spring House, PA
- research scientist Spring House, PA
- qc scientist Spring House, PA
- senior principal scientist Spring House, PA
- applied sports scientist Spring House, PA
- water quality scientist Spring House, PA
- deep learning scientist Spring House, PA
- quality control scientist Spring House, PA