Sr Scientist

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Sr Scientist What you will do Let’s do this. Let’schange the world. We are seeking a motivated Senior Scientist in mass spectrometry–based proteomics to join our talentedand collaborativeteam in Thousand Oaks, CA. In this vital role, you will deliver critical insights to support target identification and drug discovery, while advancing innovative proteomics platform technologies. You will contribute to bothpipeline advancement and screening platform innovationby developing and implementingcutting‑edge, high‑throughput proteomics approaches. This includes executing automated sample preparation and mass spectrometry analyses across a range of assays, as well as designing,optimizing, and continuouslyenhancing next‑generation screening workflows and analytical platforms. This role requires hands‑on experienceoperatingand troubleshooting high‑throughput mass spectrometry systems. Your work will play a key role in enabling innovative drug screening strategies, accelerating discovery efforts, and strengthening pipeline support. Design,develop, andoptimizehigh‑throughputmass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery Execute automated sample preparation and LC‑MS/MS analysis across abroadrange of high‑throughput proteomicsassays Collaborate closely with chemistry, biology, and disease area teams as a technical and scientific subject matter expert, contributing to data‑driven decision‑making Perform data analysis and generate insights into mechanism of action, target engagement, and selectivity using proteomicsapproaches Present research findings at internal and external meetings and effectively communicate plans, results, and analyses to cross‑functional teams Maintainaccurateand organized documentationof experiments, protocols, and analyses What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist weseekis a scientifically driven, collaborative, and innovative proteomics expert. Basic Qualifications: Doctorate degree (PhD, PharmD, or MD) with relevant experienceOR Master’s degree and 4 years ofdirectly relatedexperienceOR Bachelor’s degree and 6 years ofdirectly relatedexperience Preferred Qualifications: Doctorate degree in proteomics,chemoproteomics, biochemistry, chemistry, ora relateddiscipline Strongtrack recordin developing mass spectrometry–based proteomics assays,operatingadvanced platforms (e.g., Orbitrap Astral), and analyzing proteomics data Experience with sample preparation miniaturization and automation platforms 3+ years of experience in the biotech or pharmaceutical industry Demonstrated innovation inassay,method, or platformdevelopment Strong quantitative and computationalexpertiseinhigh‑dimensionalproteomicsdata analysis Ability to work effectively in a highly integrated, collaborative team environment, with excellent organizational, verbal, and written communication skills, and a proventrack recordof producing reliable and reproducible results. Knowledge of targeted protein degradation or E3 ligase biology is a plus What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan Stock‑based long‑term incentives Award‑winning time‑off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Sponsorship Sponsorship for this role is not guaranteed. In any materials you submit, you may redact or remove age‑identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #J-18808-Ljbffr Amgen SA