Principal Scientist, Translational Clinical Biomarkers

Principal Scientist position leading translational and clinical biomarker strategies across cardiovascular, metabolic, infectious disease, and vaccine development programs. The role involves designing decision-centric biomarker approaches, partnering with cross-functional teams, and translating complex scientific findings into actionable recommendations for program advancement.

Responsibilities

• Develop and lead integrated biomarker strategies across cardiovascular/metabolic and infectious disease/vaccine programs with cross-functional teams
• Translate disease biology and therapeutic mechanisms into translational hypotheses and fit-for-purpose biomarker approaches
• Serve as biomarker representative on program teams, providing strategic input to program-level decision-making
• Lead interpretation of biomarker and clinical datasets, translating findings into clear, actionable recommendations for stakeholders
• Mentor biomarker scientists and support publications, presentations, external collaborations, and expert interactions

Requirements

• Ph.D., M.D., or equivalent advanced degree in translational medicine, biomarker science, or drug development
• Significant experience developing and executing translational or clinical biomarker strategies in drug or vaccine development
• Scientific expertise in cardiovascular disease, metabolic disease, infectious diseases, vaccines, immunology, or related areas
• Ability to lead cross-functional scientific work in matrix environments and influence without direct authority
• Strong analytical and problem-solving skills with ability to synthesize complex datasets into decision-oriented conclusions
• Working knowledge of biostatistics, bioinformatics, quantitative sciences, and multidimensional biomarker data analysis
• Excellent written and verbal communication skills for scientific strategy communication to stakeholders