Senior / Principal Computational Biologist
Cellarity
Cellarity seeks a computational biologist to analyze single-cell omics and patient datasets, identifying disease-associated cellular states and predicting therapeutic compounds. The role involves developing analysis strategies, co-leading drug programs, and collaborating across computational, experimental, and clinical teams. Requires a Ph.D. in biology or related field, 2+ years post-doctoral experience, and expertise in single-cell transcriptomics and Python programming.
Responsibilities
- Apply computational biology and machine learning tools to high-dimensional molecular datasets including scRNA-seq and snRNA-seq disease atlases
- Develop and lead data analysis strategies across diverse biological projects with internal and external stakeholders
- Co-lead computational biology work on drug programs, ensuring study designs and data interrogation deliver high-value results
- Present findings to interdisciplinary teams spanning biologists, chemists, clinicians, and machine learning scientists
Requirements
- Ph.D. or equivalent in biology, computational biology, or related scientific field
- 2+ years of post-Ph.D. experience in relevant computational biology role
- Extensive experience analyzing single-cell transcriptomic data and large-scale atlases
- Demonstrated understanding of molecular and systems biology with diverse data types
- Python programming and scripting skills
- Strong analytical thinking, communication, and independent/collaborative work abilities
- ...integrated molecular, genetic, biophysical, computational, and engineering approaches to... ...are seeking an experienced computational biologist to support the Morphogenesis and Regeneration... ...collaboratively alongside other senior scientists and team members, this individual...Suggested
$138.6k - $257.4k
...scientific and technical leader with expertise in digital pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers.... ..., pathologists, physician-scientists, computational biologists, data scientists, and project teams to design, analyze, and interpret...PrincipalSeniorFull time$146k - $236.5k
...backed stealth AI x bio company, is seeking a Sr. Scientist / Principal Scientist, Molecular Simulations. Here you will build the... ...predictions are unreliable. Must-have Qualifications: PhD in computational chemistry, biophysics, chemical physics, structural biology,...PrincipalSenior$148k - $208k
...coordinating external scientific collaborators. Experience with automated chemistry, scientific modeling or the translation of computational findings into physical experiments. Compensation We offer competitive base compensation with bonus potential and...PrincipalSeniorFull timeWork at officeLocal areaFlexible hours- Mass Digital Health is seeking a Senior Principal Scientist to drive real-world evidence generation in Cambridge, MA. This role involves leading indication prioritization and expansion for R&D assets, leveraging large-scale EHR datasets to understand disease trajectories...PrincipalSenior
- Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA seeks an Imaging Scientist to lead AI-enabled digital pathology and biomarker workflows. You will drive scalable whole-slide image analysis and high-plex tissue imaging strategies across oncology programs...PrincipalSenior
- Scholar Rock, Inc. seeks an accomplished leader in clinical bioanalysis to join the Bioanalytical Sciences team as Principal Scientist, Bioanalytical Specialist. You will provide scientific and operational leadership across our clinical programs, representing the bioanalytical...PrincipalSenior
- ...Administration and Policy (OTAP). Job Description As a principal gifts frontline fundraiser in University Development, the Senior Director plays a leadership role in shaping... ...confidential materials with discretion. Computer literacy required must have experience with Windows...PrincipalSeniorWork at officeAfternoon shift
$115k - $215k
..., qualification, execution, and data quality oversight.Present scientific findings and strategic recommendations to project teams, senior leadership, and external collaborators in a clear, concise, and impactful manner.Skills and experience you’ll bring:PhD in Biochemistry...PrincipalSenior- ...assessment and authorization, confidentiality, integrity, and availability.Education Requirements:• Bachelor’s degree in engineering, computer science, cybersecurity, networking, or programming.• Master’s degree in engineering, computer science, cybersecurity, networking,...PrincipalSeniorFor contractorsWork at office
$105k - $120k
...Computational Biologist Application Deadline: 19 October 2026 Department: Informatics Employment Type: Full Time Location: Boston Compensation: $105,000 - $120,000 / year Description Outpost Bio is building models of how microbial communities respond to drugs and other...Full timeTemporary workHome officeFlexible hours$180k - $220k
...development and large-scale platformsExposure to AI-driven automation, agent-based systems, or adaptive workflowsBachelor’s degree in Computer Science or a related technical fieldCompensation: The base salary range for this role is $180,000-$220,000, depending on...PrincipalSeniorWork at officeRemote workWorldwide$75k - $91.5k
...The Computational Biologist I is responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators...Work experience placement$119.7k - $222.3k
...overseeing ADME/DMPK project strategy in clinical development, or in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.Extensive and in-depth knowledge of pharmacokinetics including, drug...PrincipalSeniorFull time- ...Electrical Engineer (Senior/Staff/Principal) Nanopath is developing a first-in-class in vitro diagnostics platform to transform how diseases are diagnosed. We aim to replace lengthy molecular testing workflows by bringing rapid, high-quality diagnostics closer to the...PrincipalSeniorFull timeWork at office
$150k - $225k
Sr. Principal Systems Engineer- HanscomAs a Senior Principal Systems Engineer with MTSI you will provide technical and programmatic advice and support services... ...on a suite of advanced weapon systems, sensors, and computer processing related technologies and programs. This...PrincipalSeniorContract workWork experience placementWork at office- Everforth Apex Systems in Cambridge, MA is seeking a Senior Scientist in Toxicology to shape the preclinical safety strategy for oligonucleotide programs across all development stages, influencing discovery, development, and regulatory decisions with cross‑functional teams...Senior
- ...Laboratory is seeking a highly motivated and multidisciplinary biologist to support research and development efforts focused on... ...challenges. We are looking for an individual with expertise in computational biology, data science, and biodefense, who can contribute to...
$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge, MAAbout the JobImmunology and Inflammation Therapeutic AreaWe have an exciting opportunity to join Sanofi's Translational Biology team as a Senior Principal Scientist within the Type 2 Immunology...PrincipalSeniorFull time$188k - $282k
...patterns and technology to support AI adoption at scale. As a Senior Principal AI Engineer in the Data Platforms team, you will unlock and... ...understanding of agile methodologies and practices. Bachelor's degree in computer science, Software Engineering, or related field, or relevant...PrincipalSeniorFull timeSummer work$168k - $252k
Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week$108k - $209k
...over 100 groundbreaking companies since 2000, including Moderna. The Role We are seeking an experienced, creative, and talented Principal / Senior Software Engineer. The ideal candidate will have a strong background in software and product development, with the ability to...PrincipalSenior$230k - $295k
...and everyone is a stakeholder.As a Sr. Principal Product Manager on the Circle product team... ...for money.Collaborating with senior product leadership and other product managers... ...management skills.Bachelor’s or Master’s in Computer Science, Engineering, Economics, or a related...PrincipalSeniorFlexible hours$143k - $193.05k
...truly BELIEVE in what they're doing!Job Description Summary:The Senior Principal Software Engineer serves as a technical leader for the... ...communication and collaboration skills.Ph.D. or Master’s degree in Computer Science, Database Systems, Computer Engineering, or a related...PrincipalSeniorFull timeRemote work$168k - $252k
...systems across drug discovery. Working at the intersection of Computational Drug Design, project teams, Data & Methods, and Digital Technology... ...to influence scientists, engineers, data scientists, and senior leaders across a matrixed organization.Education and ExperiencePh...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week- Akamai Technologies GmbH is seeking a Senior Product Manager for Core Compute to define and guide the product strategy for their compute offerings. This role involves connecting technical hardware with developer experiences and overseeing the compute lifecycle within a...Senior
- Senior, Principal or Lead Software Engineer, Artificial Intelligence, fully remote, 145k to 195k base, bonusCompensation Commensurate with... ...regulations.Qualification Bachelor’s and/or advanced degree in Computer Science or related technical disciplineStrong experience in...PrincipalSeniorPermanent employmentH1bRemote workVisa sponsorship
$128.6k - $210k
The Senior Toxicologist utilizes their scientific expertise and regulatory experience to lead nonclinical development programs with guidance from their direct supervisor working effectively within cross‑functional project teams. The Sr. Toxicologist will demonstrate a...SeniorContract work$188k - $282k
Job DescriptionVertex is seeking a Senior Principal AI Engineer to design, build, and optimize the shared platform capabilities that power... ...platform strategy Required Qualifications Bachelor’s degree in Computer Science, Software Engineering, Machine Learning, Data...PrincipalSeniorFull timeSummer work$142.5k - $256.5k
...seeking a talented, experienced, and highly motivated Principal Scientist to support computational protein design across therapeutic research. This role... ...science, preclinical development, external partners, and senior scientific stakeholders.Strong publication record or...PrincipalPermanent employmentFull timeWork at officeWork from home
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior / Principal Computational Biologist. Be the first to apply!
- senior mulesoft developer Somerville, MA
- senior mainframe developer Somerville, MA
- senior level Somerville, MA
- senior network engineer remote Somerville, MA
- senior manager product development Somerville, MA
- senior implementation engineer Somerville, MA
- senior manager creative operations Somerville, MA
- senior medical science liaison Somerville, MA
- senior manager m&a tax Somerville, MA
- senior manager product engineering Somerville, MA


