Associate Scientist - Cellular Assay Development, Functional Genomics

Career CategoryScientificJob DescriptionJoin Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Associate Scientist - Cellular Assay Development, Functional GenomicsWhat you will doLet’s do this. Let’s change the world. In this vital role you will be part of a dynamic, cross-functional team to advance target and biological discovery across Amgen’s therapeutic areas.Key Responsibilities:Support the execution of functional arrayed genomic screens in advanced in vitro models in collaboration with therapeutic area partners. Carry out mammalian cell culture, transfection, transduction, and functional assays to enable functional, arrayed genomic screens; experience with iPSC culture and differentiation preferred. Optimize and miniaturize cell-based assays for high-throughput automated screening. Leverage functional assays, particularly high-content imaging, to profile cellular phenotypes and states. Partner with TD&B and cross-functional team members, including automation colleagues, to accelerate model deployment and reproducibility. Collaborate with Amgen therapeutic area scientists to define requirements, ensure biological relevance, and deliver systems that enable mechanistic and translational insights. Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen’s pipeline.What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a researcher with these qualifications.Basic Qualifications:Master’s degree and 1 year of scientific/drug discovery experience and track record of scientific excellence and productivityORBachelor’s degree and 3 years of scientific/drug discovery experience and track record of scientific excellence and productivityPreferred Qualifications:M.S. degree in cell biology, molecular biology, biomedical engineering, or related discipline, or B.S. degree with commensurate scientific/drug discovery experience and track record of scientific excellence and productivity Proficiency with mammalian cell culture, including immortalized and primary lines required; experience with iPSC culture preferred Experience with gene editing/delivery techniques, i.e. CRISPR/Cas9, lentiviral transduction, and transient transfection Experience with cellular assay optimization and miniaturization; familiarity working with plate-based assays and associated equipment/automation Strong hands-on experience with functional assays, particularly high-content imaging Familiarity with high-throughput sreening metrics (e.g. Z’, S/B, MSMR) Demonstrated ability to collaborate with cross-functional teams to translate disease biology into experimental models Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environmentWhat you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accountsA discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plansFlexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.Apply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.SponsorshipSponsorship for this role is not guaranteed.As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation..Salary Range94,340.65USD -127,637.35 USDSummaryLocation: US - California - Thousand OaksType: Full time