Regional Business Director, Mid-Atlantic

MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY The Regional Business Director (RBD) is a first-line field leader responsible for leading, coaching, and developing a team of (7) Regional Account Managers to deliver strong, sustainable business performance and meaningful patient impact across an assigned region. The RBD translates national and zone strategy into focused local execution, builds a culture of continuous learning and accountability, and ensures the team operates with clinical credibility, business discipline, and a deep commitment to patients and caregivers. This leader will create clarity in a complex rare disease environment, set high standards for execution, and develop talent through frequent field coaching, timely feedback, individualized development plans, and stretch opportunities. The RBD will also serve as a trusted cross-functional partner, bringing forward actionable field insights and aligning Marketing, Medical Affairs, Market Access, Patient Services, Commercial Training and Effectiveness, Operations, and Advocacy around the needs of customers, patients, and the business. Assigned Area: NY, NJ, PA, MD, DC, VA JOB FUNCTIONS/RESPONSIBILITIES Regional Strategy & Performance Leadership - Translate national and zone priorities into a focused regional business plan with clear objectives, account priorities, resource allocation, and measures of success. - Set a disciplined operating rhythm that includes field coaching, business reviews, performance tracking, opportunity planning, and rapid course correction. - Use data, market intelligence, and field insights to identify growth opportunities, anticipate barriers, and improve execution across the region.

- Own regional results and resource stewardship, including budget management, forecasting, and alignment of team activity to the highest-impact opportunities. People Leadership, Coaching & Development - Recruit, onboard, develop, engage, and retain high-performing Regional Account Managers who demonstrate strong clinical credibility, business judgment, and patient focus. - Spend meaningful time in the field observing customer engagement, coaching in the moment, reinforcing strengths, and addressing capability gaps through clear, actionable feedback. - Create individualized development plans, provide stretch opportunities, and build succession and promotion readiness across the team. - Set clear expectations and hold self and team accountable for behaviors, execution quality, and results; address performance concerns promptly, consistently, and fairly. Customer, Account & Patient Impact - Ensure the team develops thoughtful account strategies that reflect local patient journeys, referral networks, access dynamics, customer needs, and competitive realities. - Raise the quality and consistency of customer engagement across pediatric and adult hepatology and gastroenterology settings, including priority systems and centers of excellence. - Support compliant coordination across field partners to help remove appropriate barriers in the patient journey from identification through treatment initiation and persistence. - Promote a customer’s experience grounded in trust, empathy, responsiveness, and follow-through with healthcare professionals, and care teams. Clinical & Business Acumen - Build a team that can confidently bridge science and strategy in a high-science rare disease market.