Senior Scientist

Career Category Research Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist What You Will Do Let’s do this. Let’s change the world. Amgen is seeking a Senior Scientist to join our Pharmacokinetics, Drug Metabolism & Bioanalytical (PKDM-BA) team in Thousand Oaks, California.. The successful candidate will be able to work both independently and in collaboration with cross-functional partners, including protein therapeutics, medicinal chemistry, pharmacokinetics, toxicology, clinical pharmacology and regulatory affairs. Together, we design and validate quantitative methods that support drug candidate identification, preclinical development, clinical evaluation and regulatory submissions. Key Responsibilities A Senior Scientist at Amgen is responsible for supporting all facets of the bioanalytical method lifecycle from drug development through clinical trial support as a subject matter expert. You will design, lead, and participate in the execution of experiments to support development, validation and production phases for quantitative bioanalytical methods. You will contribute to optimizing study protocols, reviewing experiments, and authoring bioanalytical reports. Your expertise will be used to improve bioanalytical methods, lead troubleshooting efforts, and ensure quality. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist, we seek is a scientifically driven, collaborative, and innovative expert. Basic Qualifications Doctorate degree OR Master’s degree and 2 years of pharmaceutical, biotechnology, CRO, or related scientific experience experience OR Bachelor’s degree and 4 years of pharmaceutical, biotechnology, CRO, or related scientific experience experience Preferred Qualifications 6+ years of laboratory experience. Experience in immunology, immunochemistry, biochemistry, cell biology, or related disciplines. Ligand binding assay experience. Experience with biosimilars, oligonucleotide and antibody drug conjugates a plus. Working knowledge of GxP regulations and bioanalytical requirements in drug development. Bioanalytical Principal Investigator, or functional equivalency, highly desired. Ability to work independently on tasks with strong critical thinking and problem solving skills. Experience with automated liquid handlers (e.g. Tecan, Hamilton) Proven ability to communicate scientific concepts effectively to audiences with varying levels of technical expertise. Demonstrated commitment to scientific excellence, innovation and quality. Strong collaboration, verbal communication and technical writing skills. Supervisory experience is valued. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Salary Range 126,354.20USD -170,949.80 USD Equal Opportunity Statement Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit and follow us on #J-18808-Ljbffr Amgen Inc. (IR)