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Computational Protein Engineer

Gables Search Group

Protein Modeling Specialist

We are seeking a skilled Protein Modeling Specialist to drive innovative antibody and protein engineering projects in Rockville, Maryland. This role involves utilizing computational tools and wet-lab techniques to enhance research outcomes and facilitate discovery.

Join a dynamic biotechnology organization that encourages independence, collaboration, and impactful scientific endeavors.

Responsibilities
  • Lead antibody and protein engineering initiatives, focusing on affinity maturation, novel binder development, and multispecific antibodies
  • Develop workflows for protein expression, purification, and analytical characterization across various platforms
  • Create binding, functional, and biochemical assays to assess engineered candidates
  • Utilize tools like Rosetta, AlphaFold, and ProteinMPNN to prioritize designs and inform laboratory strategies
  • Collaborate with computational scientists and structural biologists to implement modeling insights in experimental projects
  • Provide technical guidance on complex, interdisciplinary research endeavors
  • Present project updates, findings, and recommendations to scientific stakeholders
Requirements
  • PhD in molecular biology, biochemistry, protein science, or similar field
  • Industry background in hands-on protein engineering or antibody research
  • Proficiency in protein expression, purification, characterization, and assay development
  • Experience with bispecific antibodies, multispecific proteins, nanobodies, or related modalities
  • Familiarity with computational protein design and structure prediction tools
  • Evidence of scientific contributions through patents, publications, or successful development programs
  • Capability to lead technical projects and collaborate effectively across scientific domains

Take the opportunity to be part of a team where computational design and experimental protein engineering intersect to drive significant scientific breakthroughs.

Vacancy posted 5 days ago
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