Medical Director

Insilico Medicine is a clinical-stage biotechnology company that integrates generative AI with biology, chemistry, and clinical trial analysis to accelerate drug discovery and development. The company’s proprietary AI platforms leverage deep generative models, reinforcement learning, transformers, and other advanced machine learning techniques to identify novel targets and design new molecular structures with specific desired properties. Insilico Medicine focuses on developing innovative therapies across multiple disease areas, including cancer, fibrosis, immune and central nervous system disorders, infectious and autoimmune diseases, and aging-related conditions. Joining Insilico Medicine offers the opportunity to work at the intersection of AI and medicine, contributing to breakthrough solutions that may transform patient care worldwide. Job Title: Associate Medical Director / Medical Director / Senior Medical Director Job Summary: We are seeking a highly motivated clinical trial physicianwith expertise in oncology to join our clinical development team. The ideal candidate will provide medical support in early - phase oncology trials (Phase I/II) in the US, ensuring scientific rigor and patient safety while collaborating cross-functionally to advance our pipeline. Key Responsibilities: Serve as the medical lead for early-stage oncology clinical trials, providing oversight of protocol development, medical monitoring, and data interpretation. Partner with Clinical Operations, Biostatistics, and Regulatory teams to drive trial execution and meet key milestones. Build and maintain scientific relationships with U.S. investigators, clinical sites, and key opinion leaders (KOLs) to support study conduct, enrollment strategies, and clinical development objectives. Provide medical and scientific leadership to optimize trial design and address complex clinical and scientific questions arising throughout the study lifecycle. Participate in regulatory interactions, including support for FDA meetings and responses to health authority inquiries, as appropriate. Contribute to translational research efforts, bridging preclinical findings to clinical applications. Ensure compliance with GCP, ICH guidelines, and internal SOPs. Requirements: Education & Qualifications: MD required. Fluent English communication skills (written and spoken) are required to effectively operate in a global working environment; proficiency in Mandarin Chinese would be considered a strong asset. Experience: 5–10 years of experience in oncology, with direct exposure to early-phase clinical development programs, including Phase I and Phase II studies. Demonstrated hands‑on experience with protocol development, medical monitoring, safety reviews, and interpretation of clinical data. Experience engaging with investigators, clinical trial sites, and key opinion leaders (KOLs) to support study execution and scientific exchange. Familiarity with regulatory interactions and supporting communications with health authorities, including the FDA, is preferred. Experience working within cross‑functional clinical development teams, including Clinical Operations, Biostatistics, Regulatory Affairs, and Translational Medicine. Prior experience in biotechnology, pharmaceutical, or oncology‑focused clinical development environments is strongly preferred. Proactive communicator : Ability to articulate complex medical concepts to diverse stakeholders. Collaborative mindset : Thrives in cross‑functional teams (e.g., with Clinical Operations, Data Science). Adaptability : Comfortable navigating ambiguity in fast‑paced R&D environments. Patient‑centric mindset: Maintains focus on patient outcomes and unmet medical needs throughout the drug development process. Innovation orientation: Embraces new technologies, including AI‑enabled approaches to drug discovery and development. Global perspective: Experience working effectively across cultures, geographies, and time zones within international teams. #J-18808-Ljbffr