Postdoc Scientist: Mechanistic Modeling for Biocatalysis
BioSpace
BioSpace is seeking a scientist to develop predictive mechanistic models and computational workflows to optimize the biocatalytic assembly of oligonucleotides. You will leverage high‑throughput experimentation to parameterize kinetic models and collaborate with multidisciplinary teams to accelerate process development. Requirements include a PhD in chemical engineering, chemistry, or a related field with modeling and simulation experience; proficiency in MATLAB or Python is highly preferred, and #J-18808-Ljbffr BioSpace
- The scientist will develop predictive mechanistic models and computational workflows to optimize the biocatalytic assembly of oligonucleotides. This involves leveraging high-throughput experimentation to parameterize kinetic models and collaborating across multidisciplinary...SuggestedFlexible hours
$146k - $236k
...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms... ...behind Flagship’s drug development and investment decisions through mechanistic modeling and quantitative analysis. The individual will work...Suggested$126k - $234k
...Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal ScientistLocation... .... We are seeking a translational modeler eager to accelerate oligonucleotide therapeutics... ...systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions...SuggestedFull time$170k - $200k
...looking for a talented Machine Learning Scientist who is passionate about delivering impactful... ...machine learning and deep learning models based on financial and other modalities... ...related field2+ years of relevant industry or postdoc experienceSolid understanding of...For PostDocFull timeWork at office$126k - $234k
...radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team... ...development and application of in vivo models for evaluating novel cancer therapies... ...5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industryDeep...For PostDocFull timeRemote work$100k - $181.5k
...visit SummaryWe are seeking an exceptional Scientist or Senior Scientist to lead and support... ...and experience designing and executing mechanistic and pharmacology studies that bridge in... ...studies using state-of-the-art models and technologiesLead target validation efforts...For PostDoc$100.5k - $145.17k
Job Title: Senior Scientist, Systems BiologyLocation: Cambridge, MAAbout the JobAs a Senior... ..., generating actionable mechanistic insights and novel target hypotheses that... ...innovative algorithms and computational models.Contribute to the evaluation and application...For PostDocFull time- ...Company in Boston is seeking a Postdoctoral Scientist to investigate α-synuclein biology and... ...in disease. You will build cellular models and apply biochemical readouts in a collaborative... ...a strong publication record. Fixed-term postdoc with potential for full-time...For PostDocFull timeFixed term contract
- ...Pioneering and ProFound Therapeutics are seeking a Scientist or Senior Scientist to lead discovery... ...disease. The role focuses on target validation, mechanistic studies, and translational biology bridging in vitro and in vivo models. Ideal candidates bring a PhD in a relevant...For PostDoc
- ...in Boston, MA is seeking a Translational PK/PD Senior Scientist to design and execute modeling analyses that guide drug discovery for biologics, proteins... ...and Translational divisions while leading or contributing to mechanistic modeling projects with #J-18808-Ljbffr Merck
- ...in physics to test the reasoning capabilities of large language models (LLMs). You’ll create physics problems, analyze model responses... ...“Physicist” roles. Physics Expert - AI Trainer (Ph.Ds or Postdocs) We’re unlocking community knowledge in a new way. Experts add...For PostDocContract workFor contractorsFreelanceRemote workWorldwide
- ...Job Description Job Description Scientist/Senior Scientist, Biology Lead – Kidney Experience... ...translationally relevant kidney disease models to build and lead our kidney biology... ...platforms that enable target discovery, mechanistic validation, therapeutic screening, and...For PostDoc
- ...matters for patients, we invite you to join us. Postdoctoral Scientist - Neuroscience (Synuclein Biology) Position Overview... ...engineered cellular systems, and iPSC-derived neuronal disease models to build a mechanistic foundation for new therapeutic strategies in...For PostDocFull timeH1bVisa sponsorshipWork visa
- Lilly is seeking a highly motivated postdoctoral scientist to join the Global PKPD group, developing Quantitative Systems Pharmacology (QSP) models and applying AI-powered approaches to integrate biology, pharmacology, and data for drug discovery decisions. The role involves...For PostDocFixed term contract
- ...responses to cancer therapies. This role blends computational biology, genomics, and AI, using clinical trial samples to build predictive models of treatment outcomes. You will develop pipelines for integrating RNA-seq, ATAC-seq, ChIP-seq, spatial transcriptomics and single-...For PostDoc
$70k - $92.67k
...publications. Ideal candidates should have a Ph.D. in neuroscience, strong experimental skills, and experience with RNA-seq and rodent models. The position offers a pay range between $70,000 and $92,666.67 per year, in addition to a comprehensive benefits package. #J-1880...For PostDoc$58k - $123.2k
...seeking a highly motivated Postdoctoral Scientist to join the Lilly Gene Therapy (LGT) organization... ...various in vitro and in vivo system. Mechanistic Pathway Analysis Develop and apply... ...disease. In Vivo Study Design & Model‑Based Investigation Collaborating with...For PostDocFull timeFixed term contractH1bVisa sponsorshipWork visaFlexible hoursShift work$58k - $123.2k
...We are seeking an ambitious postdoctoral scientist with strong research and communication... ...human iPSC-derived tri- and quad-culture models containing excitatory neurons, inhibitory... ..., transcriptomic) to establish mechanistic links between genetic perturbations and...For PostDocPermanent employmentFull timeTemporary workH1bVisa sponsorshipWork visaFlexible hours$58k - $123.2k
...PKPD group deploys a powerful suite of model-based approaches—including PBPK, PK/PD,... ...curious, and collaborative postdoctoral scientist to join the Global PKPD group working... ...an ODE-based QSP model structure that mechanistically captures the relevant drug pharmacokinetics...For PostDocFull timeTemporary workH1bVisa sponsorshipWork visaFlexible hours- ...Research Fellow to join the Center for Functional Cancer Epigenetics. The project focuses on multiomic analyses and developing predictive models of therapy response using clinical trial data. You will collaborate with computational biology, genomics, and clinical teams,...For PostDoc
$178.5k - $257.83k
Job title: Distinguished Scientist, Transgenic Model and TechnologyLocation: Cambridge, MAAbout the jobThe Translational In Vivo Models (TIM) department within Sanofi's R&D is seeking an exceptional Distinguished Scientist to lead our Transgenic Model & Technology (TMT)...Full timeContract workWork at officeRemote workFlexible hours$192k - $265k
The Role: Generate:Biomedicines is seeking a creative, rigorous, and execution-oriented machine learning scientist to join our Model-Driven Design team. This role will focus on building the ML methods, data strategies, and closed-loop systems that determine what we design...Work at officeShift work- ...’s Neurodegeneration Biology group in Boston seeks a Postdoctoral Scientist to investigate α-synuclein biology, aggregation, and disease mechanisms. You will use physiologically relevant cellular models, including engineered cell lines and iPSC-derived neurons, to study...For PostDoc
- ...seeking a highly motivated, collaborative, and innovative Senior Scientist to lead high-impact translational research at the intersection... ..., patient-derived induced pluripotent stem cell (iPSC) neuron models, and advanced bioinformatics/multi-omic pipelines to systematically...For PostDocFull timeRemote work
$116k - $182.27k
...DescriptionJob DescriptionAbout the role:We are seeking a Research Scientist to help shape the future of AI-enabled drug discovery at Takeda... ....How you will contribute:Develop and iterate on deep learning models across the molecular modeling stack — structure prediction,...For PostDocMinimum wageLocal area$126k - $181.5k
...necessary for training the next generation of generative chemistry models to unlock the future of small molecule drug discovery. FL129 is... ...to this challenge and is recruiting a team of top-tier scientists to build this powerful and first-in-category platform. This is...For PostDocContract work$145k - $161k
...OverviewWe are seeking an exceptionally driven, discovery-minded Senior Scientist to join our Platform Technology & Innovation team. This team... ...technologies from in vitro systems into in vivo animal models, using non-viral (e.g., LNP) or viral (e.g., AAV) delivery systemsWorking...For PostDocFull timeTemporary work- Lilly invites a postdoctoral scientist to join a high‑visibility program at the intersection of human iPSC biology, neuroscience, and functional... ...genomics. You will develop iPSC-derived neuron-glia co‑culture models and apply MEA and patch‑clamp methods to study network dynamics...For PostDoc
- Lilly seeks a postdoctoral scientist to advance a cutting-edge human iPSC-derived co-culture platform studying neuron-astrocyte interactions... ...psychiatric contexts. You will develop tri- and quad-culture models, apply MEA and automated patch-clamp, and use LNP delivery for...For PostDoc
- ...methodological innovation by identifying, evaluating, and deploying emerging approaches (e.g., multi-omics integration, polygenic modeling, rare variant aggregation, AI/ML-enabled prioritization).Help to establish best practices for data organization, knowledge management...For PostDocFull timeTemporary workLocal areaFlexible hours
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