Post-Doctoral Scientist - Mechanistic Modeling & Simulation(SMDD)
BioSpace
The scientist will develop predictive mechanistic models and computational workflows to optimize the biocatalytic assembly of oligonucleotides. This involves leveraging high-throughput experimentation to parameterize kinetic models and collaborating across multidisciplinary teams to accelerate process development. Requirements: Candidates must hold a PhD in chemical engineering, chemistry, or a related field with expertise in modeling and simulation. Proficiency in programming tools like
MATLAB
or Python and experience with biocatalytic systems are highly preferred. Key Skills: Mechanistic Modeling Simulation Biocatalytic Reaction Systems Kinetic Modeling MATLAB Python Nucleic Acid Thermodynamics High-Throughput Experimentation Lab Automation Chemical Engineering Oligonucleotide Synthesis Enzymatic Ligation Process Optimization Scientific Writing Collaboration Data Analysis Benefits: Company bonus 401(k) Pension Vacation benefits Medical insurance Dental insurance Vision insurance Prescription drug benefits Flexible spending accounts Life insurance Death benefits Employee assistance program Fitness benefits #J-18808-Ljbffr BioSpace$58k - $123.2k
...Design and Development (SMDD) is a dynamic group... ..., pharmaceutical scientists, analytical chemists... ...the engineer will use mechanistic modeling to develop a... ...Laboratories (LRL) post-doctoral program funds challenging... ...experience in modeling and simulation Qualified applicants...SuggestedFull timeTemporary workFixed term contractH1bVisa sponsorshipWork visaFlexible hours$126k - $234k
...Internal Title: Principal Scientist II or Senior Principal... ...a translational modeler eager to accelerate oligonucleotide... ...(QSP) and mechanistic PBPK/PD approaches to... ...reports to a Modeling and Simulation (M&S) team lead within... ...) role.This is a dual posting. The final level &...SuggestedFull time$105.28k - $213.8k
Modeling & Simulation Research Scientist United States, Cambridge -Us Digital Technology & Research, Engineering & Design, Manufacturing Schlumberger-Doll Research (SDR), SLB's global research and innovation center, is seeking a Modeling & Simulation Research Scientist...SuggestedContract workFor contractorsLocal areaImmediate start- ...thinking environment where collaboration, innovation, and high-quality biotherapeutics development go hand in hand. As a Scientist, PK/PD Modeling & Simulation, you will be responsible for developing, validating, and applying population PK, PK/PD, exposure-response and QSP...Suggested
$142.8k - $193.2k
We are looking for an Applied Scientist to join the Robotics Simulation team at Amazon Robotics. In this role you will design, build, and validate the simulation... ...who consume your environments and pipelines for their model development.This is a hands-on, execution-focused role....SuggestedFull timeTemporary workSeasonal workFlexible hours$146k - $236k
...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms... ...behind Flagship’s drug development and investment decisions through mechanistic modeling and quantitative analysis. The individual will work...$180k - $258.75k
...cross‑functional expertise across hardware, simulation, perception, controls, and machine... ...robots and general‑purpose robot foundation models. Implement, extend, and create state‑of‑... .... Collaborate with internal research scientists and our partner labs at top academic research...Local areaShift work$178.5k - $257.83k
Job title: Distinguished Scientist, Transgenic Model and TechnologyLocation: Cambridge, MAAbout the jobThe Translational In Vivo Models (TIM)... ...Developmental Biology, or a related discipline• Extensive post-doctoral or industry experience in mouse molecular genetics and transgenic...Full timeContract workWork at officeRemote workFlexible hours- Alnylam Pharmaceuticals, Inc. in Cambridge, MA is seeking a DMPK Scientist to design and interpret in vitro and in vivo ADME and PK/PD... ...and candidate selection. You will build quantitative models and simulations using Phoenix WinNonlin, Monolix, and R, integrate PK/PD and...
- Schlumberger Limited in Cambridge, Massachusetts, is seeking a Modeling & Simulation Research Scientist to join the Geosciences Department. You will develop and validate advanced numerical models for subsurface processes, collaborating with geoscientists, reservoir engineers...
- Hemab is seeking a Scientist, PK/PD Modeling & Simulation in Cambridge, MA to develop population PK/PD, PBPK and QSP models to support dose selection and trial design. You will collaborate with clinical pharmacology, nonclinical, and regulatory teams to inform clinical...
$60 - $65 per hour
Job Description Research Scientist, Human Cell Models — Immunology & Molecular Cell Biology Location:... ...cell models, assay development, and mechanistic biology. Role Summary Vertex is seeking... .../HR Requisition Disclaimer This job posting is for a temporary role with a third...Contract workTemporary work- ...in Boston, MA is seeking a Translational PK/PD Senior Scientist to design and execute modeling analyses that guide drug discovery for biologics, proteins... ...and Translational divisions while leading or contributing to mechanistic modeling projects with #J-18808-Ljbffr Merck
- As a VLA Research Scientist on the Atlas team, you will architect, train... ...the large-scale behavior models that enable high-performance... ...demonstrations, teleoperation, and simulation data.Develop policies capable... ...humanoids.SummaryLocation: Waltham Office (POST)Type: Full timeFull timeWork at office
- ...quantitative pharmacology and modeling, consequently guiding... ...highly motivated scientists across a broad array... ...PK/PD, PBPK, and mechanistic/systems modeling—to characterize... ...document models and simulations using tools such as... ...role at the time of posting. Base pay will be...Full timeTemporary workLocal areaFlexible hours
$122.25k - $176.58k
Job Title: Principal Scientist, Systems and Disease BiologyLocation... ...and computational models.Leading projects involving internal... ...workflows and/or complex follow-up mechanistic assays (organoid, CRISPR,... ...biology.At least 2 years of post-doctoral experience in relevant...Full time$192k - $265k
The Role: Generate:Biomedicines is seeking a creative, rigorous, and execution-oriented machine learning scientist to join our Model-Driven Design team. This role will focus on building the ML methods, data strategies, and closed-loop systems that determine what we design...Work at officeShift work$79k - $127.65k
...Career Programs Job Sub Function Post Doc — Data Analytics &... ...seeking a Translational Post Doctoral Researcher — Agentic AI for Neurodegeneration... ...Evaluating whether an AI co‑scientist can synthesize across... ...specialized, domain‑specific models for neurodegeneration Build...Temporary workFixed term contractLocal areaRemote work$260.3k - $409.7k
...opportunity for a physician-scientist to join our group as a-... ...biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and... ...applications. - Education: ~ Doctoral degree: MD or MD/PhD (or... ...role at the time of this posting. An employee's position...Full timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- Generalist is seeking a talented individual to help build the core intelligence for robotics through large-scale training of models. You will design pretraining protocols, define model architectures, and develop data strategies across multimodal datasets. The successful...
$142.22k - $172.34k
...sites in Cambridge and Seattle, scientists focus on novel targets and... ...vitro, in vivo and ex-vivo models of Cancer biology and Immuno... ...oncogenic targets and drug mechanistic studies.Interact with project... ...Qualifications:Ph.D. with post-doctoral experience and/or 1-3 years...Hourly payFull timeContract workTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$90k - $100k
Karen Clark & Company in Boston is seeking an earthquake hazard professional to enhance our global earthquake models. You will collaborate with scientists and engineers, collecting seismic data and developing seismic models. The ideal candidate will have a PhD in Seismology...- ...based at the Seaport Innovation Center in Boston. The postdoctoral scientist will extend an established tri‑culture system to disease... ...compound assessment in neurodegeneration. The role emphasizes leading model development, evaluating compounds, and generating datasets to...
$58k - $123.2k
...deploys a powerful suite of model‑based approaches—including PBPK... ...collaborative postdoctoral scientist to join the Global PKPD... ...based QSP model structure that mechanistically captures the relevant drug pharmacokinetics... ...parameter estimation, model simulations and model analysis to inform...Full timeTemporary workH1bVisa sponsorshipWork visaFlexible hours$80k - $120k
Alnylam Pharmaceuticals in Cambridge is seeking a Senior Associate Scientist to join their Research department. The successful candidate... ...experience, particularly in RNA analysis and working with rodent models. This full-time position offers a competitive salary ranging...Full time- Recentive Analytics Inc. is seeking an Optimization Scientist to join its Operations Research team in Boston. The ideal candidate will have... .... Responsibilities include developing advanced optimization models for scheduling and resource allocation and collaborating with various...
$67.86k - $95.85k
...Opportunity The Associate Research Scientist will conduct integrated... ...data and develop physics-based models (e.g., porous electrode... ...tools for data analysis and/or simulation Qualifications are normally acquired... ...lead to degrees through the doctorate in 10 colleges and schools...Work experience placementWorldwide$70k - $90k
A prominent research institution in Cambridge, MA, is seeking a Research Scientist I to develop advanced cellular models for cancer studies. The ideal candidate will hold a Ph.D. in a biological science and have 2+ years of postdoctoral or industry experience. Key responsibilities...- ...Robotics is seeking leaders in robotics research to help advance AI-powered robots through foundation models and real-world deployment. You will work across research, simulation, and hardware to push the capabilities of robotic agents and intelligent systems. We value...
$70k - $90k
Overview Research Scientist I, Cancer Cell Model Development and Resistance Project at Broad Institute of MIT and Harvard. The primary goal of this role is to develop advanced laboratory cellular models to enable functional genomics, drug screening, and drug resistance...
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