Principal, Statistician

Position Summary The Principal, Statistician will own the statistical and quantitative work that connects clinical evidence to the most important decisions Roivant makes across its pipeline. This is not a strategy role — this is a figure‑things‑out and get‑things‑done role in a high‑stakes environment with substantial ownership. We expect you to get to ground truth on the hardest clinical and scientific questions the company faces, working directly in trial datasets and translating rigorous analysis into recommendations that leadership acts on. The Principal will pressure‑test the clinical assumptions underpinning key pipeline and commercial decisions, build the statistical frameworks needed to evaluate evidence across assets, and ensure Roivant has a clear‑eyed view of what its data actually shows. The scope is intentionally broad and is well‑suited to a high‑potential individual earlier in their career with exceptional upside and a strong desire to take on responsibility. Responsibilities Clinical Trial Data & Signal Detection Work directly in ongoing and completed clinical trial datasets (CSRs, patient‑level data, interim readouts) to identify efficacy signals, safety patterns, and subgroup effects that inform go/no‑go and commercialization decisions Build rigorous statistical analyses from scratch: mixed‑effects models, longitudinal models, Bayesian frameworks, subgroup analyses, and sensitivity analyses across Roivant's pipeline assets Monitor emerging safety signals and unexpected findings in real time across ongoing studies; surface and contextualize them for leadership before they become surprises Pressure‑test clinical assumptions: challenge endpoint choices, scrutinize statistical analysis plans, and flag where the data does not support the narrative Execute focused 1‑5 day analytical sprints on the highest‑priority questions from Roivant and Vant leadership Develop a deep, differentiated read of the clinical evidence base for Roivant's near‑commercial assets: what the data shows, what it does not, and where the science is genuinely uncertain Analyze competitors' trial data, published and unpublished, with the same rigor applied to Roivant's own: endpoints, patient populations, effect sizes, and durability Synthesize findings from literature, registries, claims, and proprietary datasets into coherent evidence narratives that hold up under scrutiny Data Infrastructure & Cross‑Platform Work Drive selection and integration of the data sources needed to support portfolio decisions, including claims, labs, clinical trial data, and genomics Help build shared analytical infrastructure across Roivant and Vant companies Identify opportunities to apply consistent statistical frameworks across assets and therapeutic areas Qualifications Exceptional academic background from a top‑tier program in statistics, mathematics, computer science, or a related quantitative field Deep command of statistical and computational methods: mixed‑effects models, longitudinal analyses, Bayesian approaches, machine learning, and the judgment to know which tool fits the problem Demonstrated interest in life sciences, biology, or health. While you do not need a biology degree, you are genuinely curious about how medicines work and what clinical data means Hands‑on experience working with large, complex datasets; you have built analyses from scratch, not just run existing pipelines High capacity for learning; you pick up new domains quickly and are comfortable operating in areas where you are not yet an expert Track record of translating rigorous analysis into decisions; your numbers have changed something Able to communicate complex quantitative findings clearly to non‑technical audiences, including CEO‑level stakeholders Intensely curious, resourceful, and motivated; you run toward hard, ambiguous problem Context Roivant is preparing to become the next breakout commercial‑stage biotech, with the commercialization of brepocitinib, IMVT‑1402, and mosliciguat. Getting those launches right requires an unusually rigorous understanding of the clinical evidence that defines each market: what the data actually shows, not what anyone wishes it showed. This role ensures that understanding exists. It carries real ownership, direct exposure to senior leadership, and a trajectory that can serve as a foundation for future senior roles across the platform. This is a full‑time position. The role offers meaningful equity participation and a comprehensive company‑sponsored benefits package. Base salary will be determined during the interview process and will vary based on multiple factors, including prior experience, relevant expertise, current business needs, and market conditions. The expected base salary will generally be between $130,000 to $220,000 per year at commencement of employment, but the final salary offered may be outside this range based on individual circumstances. This position is at‑will and Roivant reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance and business and market conditions. Roivant Sciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. #J-18808-Ljbffr Roivant Sciences