Director, US TUKYSA HCP Marketing Lead

ROLE SUMMARY Join us to make history — for patients, for their families, for the future. At Pfizer Oncology, our mission is to "Outdo Cancer" by developing transformative therapies that make a meaningful impact for patients. Pfizer Oncology currently boasts an industry-leading portfolio spanning breast as well as genitourinary (GU) cancers, hematology-oncology, gastrointestinal-oncology, and thoracic cancers. The US Breast Cancer Business is one of the largest businesses within Pfizer Oncology. It is anchored by a multibillion-dollar asset IBRANCE, as well as TUKYSA in metastatic breast cancer, and a robust pipeline of breast cancer innovation. Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you — across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. At Pfizer Oncology, our mission is to "Outdo Cancer" by developing transformative therapies that make a meaningful impact for patients. Pfizer Oncology currently boasts an industry-leading portfolio spanning breast as well as genitourinary (GU) cancers, hematology-oncology, gastrointestinal-oncology, and thoracic cancers. The US Breast Cancer Business is one of the largest businesses within Pfizer Oncology. It is anchored by a multibillion-dollar asset IBRANCE, as well as TUKYSA in metastatic breast cancer, and a robust pipeline of breast cancer innovation. TUKYSA is entering one of the most consequential windows in the brand's history with the anticipated launch of the HER2CLIMB-05 first-line maintenance (1Lm) indication in human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (mBC, PDUFA Oct 17, 2026). HER2CLIMB-05 marks a new era for the Pfizer Breast Cancer Franchise, with TUKYSA poised as the franchise growth driver. TUKYSA is also indicated for HER2+ metastatic colorectal cancer (mCRC). Over the next years, several pivotal trial readouts are anticipated across both mBC and mCRC for TUKYSA. The HCP Marketing Lead is a critical strategic and operational leadership role. Operating as an individual contributor in a highly matrixed environment, the Director is the strategic architect of TUKYSA HCP marketing, owning positioning, value proposition, core claims and messaging architecture. The role leads the HCP agency partnership and serves as the primary Marketing partner to Sales for personal promotion, ensuring strategy translates into effective field execution. The Director, US TUKYSA HCP Marketing Lead will report to the Sr. Director, US TUKYSA Lead and be part of a mission-driven, innovative, and talented team of diverse colleagues, partnering closely with Sales, Insights & Analytics, Medical, Regulatory, Legal and other cross-functional partners. ROLE RESPONSIBILITIES Set and evolve the HCP marketing strategy through launch and beyond, translating emerging customer, competitive and performance dynamics into strategic, executional and investment decisions. Define TUKYSA HCP positioning, value proposition, messaging and claims architecture, ensuring compelling competitive differentiation as the market evolves. Establish HCP segmentation and targeting strategy, defining priority customers and differentiated engagement approaches in partnership with Insights & Analytics. Direct HCP personal promotion from strategy through execution, including core promotional resources, objection handling and MLR review. Direct the integrated HCP marketing tactical plan and investment portfolio, making prioritization and resource-allocation decisions across HCP Marketing and establishing success measures with Insights & Analytics. Serve as the primary Marketing partner to Sales, translating HCP strategy and messaging into effective field execution and rapidly incorporating field insights. Synthesize customer, clinical, competitive and performance insights into strategic action, continually optimizing messaging, execution and investment based on in-market learning. Drive HCP marketing execution through others, setting priorities and accountability and providing strategic direction, coaching and development to HCP marketing colleagues and agency partners Here Is What You Need (Minimum Requirements) Bachelor's Degree with 8+ years of experience; OR MBA/MS with 7+ years of experience; OR PhD/PharmD with 5+ years of pharmaceutical/biotech commercial experience, including HCP marketing Demonstrated experience developing HCP positioning, messaging, and segmentation strategies. Experience leading promotional materials through MLR review Ability to independently interpret clinical evidence, primary market research and customer insights and translate them into commercial strategy. Demonstrated success leading complex, high-impact initiatives across a matrixed organization. Demonstrated ability to influence stakeholders, coach and develop others, and achieve results through the work of other colleagues. Strong commercial judgment and demonstrated agency, investment and budget management capabilities. Strong written, verbal and executive communication skills. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Bonus Points If You Have (Preferred Requirements) Advanced degree such as MBA, PharmD, PhD or equivalent. Oncology commercial experience, particularly breast cancer or solid tumor. Launch experience in a highly competitive and evolving market Field Sales or other customer-facing experience. Experience developing integrated HCP strategies spanning personal and non-personal promotional channels. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Domestic travel of up to 20%. Last date to apply: October 27, 2026 The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information you during the first interview. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave health benefits to include medical, prescription drug, dental and vision coverage Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email View email address on click.appcast.io. 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