Director, In Vivo Pharmacology - Metabolic Disease
Jobleads-US
Pioneering Medicines in Cambridge, MA seeks a Director of in vivo Pharmacology focused on metabolic disease. You will lead in vivo pharmacology programs across obesity and metabolic diseases, mentor scientists, and drive cross‑functional collaboration with platform companies and external partners.
This on‑site/hybrid role requires hands‑on lab leadership, managing studies with CROs, and delivering strategic plans and robust biomarker readouts to advance programs toward IND‑enabling studies.
#J-18808-Ljbffr Jobleads-US$172k - $236.5k
...Medicines is seeking a highly motivated and strategic Director of in vivo Pharmacology to support a growing portfolio of assets. This key role... ...modalities using their deep expertise in obesity and metabolic diseases. The candidate will work in cross-functional teams leading...Suggested- ...Pioneering Medicines is seeking a highly motivated Director of in vivo Pharmacology to support a growing portfolio, directing in vivo efforts across obesity and metabolic diseases. The role involves leading cross-functional teams, mentoring junior scientists, and building...Suggested
- ...Pharma GroupContact: ApplicationsEmail: ****@*****.*** ResponsibilitiesStudy design and executionLead in vivo pharmacology for assigned ADC programs, from target validation through IND-enabling efficacy packages, within the strategy set by research...Suggested
$174.4k - $261.6k
...difference, there’s only one choice.Director, In vivo Expert, CVRI (... ...further strengthen in vivo disease modelling and help build up... ...alignment and timely delivery of pharmacology related deliveries to... ...cardiovascular, renal, and metabolic space;Collaborate with other...SuggestedContract workLocal area$194.1k - $305.6k
...Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB... ...collaborative Senior Director to contribute to our... ...across multiple disease indications and therapeutic... ...of in vitro and in vivo studies to understand... ...disposition on disease biology, pharmacological response (PK/PD) and...SuggestedFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$163.5k - $281.6k
...Generation Therapeutics (NGTx) team as Director of In Vitro Pharmacology. If you're driven by discovery and... ...and primary cellular systems, engineer disease-relevant models that recapitulate... ...high-dimensional dataPartner with In Vivo Pharmacology, Discovery Research, and...Flexible hours$156.9k - $247k
...of Pharmacokinetics, Dynamics, Metabolism & Bioanalytics (PDMB) is... ...collaborative Scientific Associate Director for our growing Translational... ...areas;Integrate in vitro and in vivo data to build PKPD, PBPK, quantitative systems pharmacology (QSP), or other mechanistic...Full timeFor contractorsLocal areaFlexible hours$286.9k
...Principal Scientist (Senior Medical Director) Translational Medicine,... ...potential targets to human disease in order to justify... ...development and execution of clinical pharmacology strategies for late-stage... ..., biostatistics, drug metabolism, modeling and simulation, regulatory...Full timeFor contractorsLocal areaWorldwideFlexible hours$240k - $340k
...and massively multiplexed in vivo screening to unlock tissue-targeted... ...our discovery biology and pharmacology teams, while also serving as... ..., or 7+ years for Senior Director levelDrug-hunter track record... ...fibrosis, pulmonary and kidney disease also of interest. Familiarity...$194.1k - $305.6k
...for protein therapeutics across multiple disease indications and therapeutic areas. Mentor... ...and analysis of in vitro and in vivo studies to understand the impact of drug disposition on disease biology, pharmacological response (PK/PD) and safety. Contribute...For contractorsWorldwideRelocationVisa sponsorship$165k - $200k
...Associate Director, Pharmacology Cambridge, MA Parabilis Medicines is a clinical-stage biopharmaceutical... ...medicines for patients with serious diseases by unlocking biologically important... ..., interpret, and communicate in vivo PK/PD and efficacy studies (internally...Shift work$177.5k - $232k
...Formation Bio is seeking an Associate Director, Pharmacology to join our Development team. In this role... ...fluidly across mechanisms, modalities, disease areas, and stages of development, with... ...of action, target biology, in vivo proof of concept, dose-response, pharmacodynamic...Work at officeLocal areaRelocation3 days per week$286.9k
...Principal Scientist (Senior Medical Director) Translational Medicine,... ...evaluate relevance to human disease. Develop biomarker... ...develop and execute clinical pharmacology strategies for late‑stage development... ...Medicine‑EU, Drug Metabolism/Modeling & Simulation, Regulatory...For contractorsWork at officeRemote workWorldwideMonday to FridayMonday to ThursdayShift work3 days per week- ...for the better. Chiesi Global Rare DiseasesChiesi Global Rare Diseases is a Chiesi Group’s business unit established in February 2020... ...here.Who we are looking forThis is what you will doThe Senior Director, RWE is accountable for the global real-world evidence generation...Hourly payWork at officeLocal areaRemote workRelocation packageFlexible hours
$238k - $327k
About This RoleAs the Senior Director, Head of Global Pricing and Access (V&A) for Alzheimer’s Disease, you will be at the forefront of Biogen's market access and pricing strategies, with a focus on our Alzheimer’s Disease pipeline. You will guide the development and execution...Full timeTemporary workLocal areaWorldwide$225k - $300k
## Director, Medical Affairs, Rare DiseaseApplylocations: Cambridge (US)time type: Full timeposted on: Posted Todayjob requisition id: R-21734**Title:**Director, Medical Affairs, Rare Disease**Company:**Ipsen Biopharmaceuticals Inc.**About Ipsen:**Ipsen is a mid-sized...Temporary workLocal areaFlexible hours$205k - $341.6k
...agents and combinations with bispecific antibodies across multiple disease areas (Oncology and Immunology). In this highly matrixed role,... ...laboratories and groups (e.g. BioAnalytical, Clinical Pharmacology, Molecular Profiling, CDX, Discovery Research, Analytical Innovations...Contract work$205k - $341.6k
...with bispecific antibodies across multiple disease areas (Oncology and Immunology). In this... ...clinical biomarker assays. As a Director, a typical day may include the following... ...and groups (e.g. BioAnalytical, Clinical Pharmacology, Molecular Profiling, CDX, Discovery Research...Contract workLocal area$152.6k - $283.4k
...neuroscience and cardiovascular disease areas with a robust... ...closely with clinical pharmacology and pharmacometrics... ...of preclinical in vivo and in vitro studies to... ...at the Associate Director level will have additional... ...neuroscience, cardiovascular, metabolism) and drug modalities (...Full time$196.7k - $353.4k
...RoleModerna’s Clinical and Quantitative Pharmacology (CQP) function is seeking an innovative,... ...and strategic leader to serve as Senior Director, Head of Quantitative Systems Pharmacology... ...and application of mechanistic models (disease progression, target engagement, immune...Permanent employmentFull timeWork at officeWork from home$183k - $252k
About the RoleThe Global Associate Medical Director, Evidence Generation and Education is a key member of the Global Medical Rare Disease team, reporting into the Rare Disease Global Medical Lead and supporting the Global Medical Directors, Rare Disease - ALS and SMA....Full timeTemporary workLocal areaWorldwide- ...Ipsen Group in Cambridge, MA seeks a Director of Medical Affairs for Rare Disease to lead the strategy for pediatric cholestatic diseases. This role involves collaborating with internal teams and external stakeholders to ensure alignment in medical strategies. The...
$165k - $200k
...Associate Director, Discovery DMPK Cambridge Parabilis... ...patients with serious diseases by unlocking... ...Parabilis Medicines' Drug Metabolism and Pharmacokinetics (... ...in vitro and in vivo ADME studies to inform... ...medicinal chemistry and pharmacology to guide chemical design...Shift work- ..., and combinations with bispecific antibodies across multiple disease areas (Oncology and Immunology). In this highly matrixed role... ...Regeneron laboratories and groups (e.g., BioAnalytical, Clinical Pharmacology, Molecular Profiling, CDX, Discovery Research, Analytical...
- Ipsen is seeking a Director, Epidemiology and RWE Sciences in Cambridge, MA. This role leads the global evidence strategy for Rare Diseases, overseeing real-world evidence generation for various products. The ideal candidate will have over 8 years of experience in epidemiology...
- ...to execute and adapt global pricing strategies. Develop and communicate long-range Value and Access strategies for the Alzheimer’s Disease and Neurodegeneration portfolio. Represent Biogen at scientific and technical external events to advocate and advance access...Worldwide
$214.9k - $358.1k
...Development Team including but not limited to clinical, clinical pharmacology, statistics, safety, commercial, patient access, and... ...of the complexities and recent developments in the principal disease areas; confident discussing scientific / mechanistic aspects of...Permanent employmentFull timeH1bLocal areaWorldwideVisa sponsorshipWork visaRelocation package2 days per week- ...flexibility and capability to function at a high level across multiple disease areas, including the therapeutic area of Dementia, and will be... ...Safety, Research, Regulatory, Clinical Operations, Clinical Pharmacology, Quantitative Sciences, Translational Sciences, Worldwide...Worldwide
- ...multi-disciplinary Clinical Pharmacology development plans and strategies... ...explaining MoA and disease specifics, available relevant... ...meetings. Qualifications Associate Director, Clinical Pharmacology PhD... ...systems pharmacology, Drug metabolism/Transporters. Excellent interpersonal...
$174k - $196k
...Associate Director, Clinical Pharmacology Cambridge, Massachusetts, United States City Therapeutics is advancing a next-generation platform for RNAi... ...of transformative medicines for patients with serious diseases. We are seeking a highly motivated and scientifically rigorous...Work at officeWork from homeFlexible hours
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