Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Sr Director R&D DDSAI Discovery Biologics

$196k - $342.7k
Full-time

Johnson & Johnson

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Data Analytics & Computational Sciences

Job Sub Function:

Data Science

Job Category:

People Leader

All Job Posting Locations:

Spring House Pennsylvania United States of America

Job Description:

J&J Innovative Medicine is hiring for a Sr Director - R&D DDSAI - Biologics Discovery opportunity. This position has a primary location of Spring House PA and will require up to 25% travel.

J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology immunology neuroscience cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market from patients to practitioners and from clinics to hospitals. To learn more about Johnson & Johnson Innovative Medicine visit the Opportunity

Help shape the next generation of Discovery Biologics by bringing together exceptional science biologics data lab robotics and AI to discover better medicines for patients faster.

Johnson & Johnson Innovative Medicine is seeking an accomplished scientific and organizational leader to oversee all Data & AI activities supporting Discovery Biologics. Your mission will be to help our scientists discover the best possible molecules with speed to double our rate of clinical candidates in our already industry leading organization.

You will set the organizations data and AI strategy for Discovery Biologics build outstanding multidisciplinary capabilities and translate advances in Tech Data & AI into productive scientific practice. Working closely with Discovery Biologics scientists and IT you will connect molecular design experimentation data generation and analytical insight into a new AI-Native Biologics engine that learns from every experiment.

Key Responsibilities

Set the Data & AI Strategy

  • Define and execute an integrated strategy spanning data advanced analytics machine learning and AI across Discovery Biologics.
  • Translate scientific and portfolio priorities into a focused multiyear roadmap balancing immediate discovery needs with differentiated long-term capabilities.
  • Oversee the Data & AI project portfolio aligning investments resources partnerships and delivery priorities with scientific impact.
  • Serve as a senior strategic partner to the Discovery Biologics leadership team communicating opportunities progress risks and investment tradeoffs clearly.

Make AI Productive in Biologics Discovery

  • Lead the development evaluation and deployment of AI approaches that support antibody engineering lab data analytics profiling and candidate optimization.
  • Partner with experimental scientists & IT to define the questions that matter design meaningful evaluations and translate process opportunities into project investments with clear measurable impacts
  • Advance predictive generative and multimodal approaches where they offer demonstrable value in collaboration with our Discovery modeling and IT teams.
  • Ensure promising methods become reliable scalable capabilities embedded in discovery workflows rather than isolated proofs of concept.

Connect Molecular Design and Experimental Learning

  • Partner with scientific and automation teams to connect molecular design experimental execution data capture analysis and subsequent design decisions.
  • Ensure experimental data continuously strengthens models and scientific understanding.
  • Enable scientists at the center of AI-enabled discovery through the use of AI tools and lab automation. Combining computational recommendations with experimental evidence and scientific reasoning.

Build Connected AI-Ready Data Foundations

  • Oversee the data strategy and engineering capabilities needed to capture integrate curate and reuse Discovery Biologics data.
  • Establish durable data products connecting sequence assay results profiling biophysical measurements automation outputs and external partner datasets.
  • Champion FAIR principles semantic alignment metadata quality shared ontologies and provenance.
  • Partner with downstream development colleagues to maintain continuity of molecular knowledge and developability evidence across the Discovery-to-CMC interface.

Deliver Trusted Sustainable Capabilities

  • Partner with technology platform and enterprise AI teams to align scientific requirements with scalable architecture and infrastructure.
  • Oversee the full lifecycle of analytical and AI solutions including development testing deployment monitoring maintenance and improvement.
  • Promote reusable capabilities and standards that strengthen collaboration across R&D.

Build Talent and Scientific Adoption

  • Attract exceptional talent and develop leaders who can bridge experimental science and computational innovation.
  • Foster a culture of scientific rigor curiosity collaboration and accountability for usable outcomes.
  • Strengthen scientists data and AI Literacy through partnership coaching and practical demonstrations of value.

Shape External Innovation

  • Build strategic collaborations with academic groups biotechnology companies technology partners and scientific consortia.
  • Evaluate emerging methods and external capabilities against Discovery Biologics priorities.
  • Represent the organization in scientific and industry forums and support publications and intellectual property where appropriate.

Required Qualifications

Proposed requirements for this role:

  • Ph.D. or equivalent experience in Computational Biology Bioinformatics Protein Engineering Biomedical Engineering Computer Science AI/ML Applied Mathematics or a related discipline.
  • 12 years of relevant experience applying data science computational methods or AI in drug discovery or related scientific environments including 7 years building and leading scientific or technical teams.
  • Substantial experience in biologics discovery with the scientific depth to partner credibly with antibody and protein engineering scientists.
  • Demonstrated success translating ML/AI and data capabilities into experimentally grounded discovery decisions and adopted scientific workflows.
  • Strong technical judgment across ML/AI scientific computing data engineering and model lifecycle management.
  • Experience setting strategy prioritizing investments and delivering complex programs through multidisciplinary teams and matrix partnerships.
  • Expertise in building reusable interoperable data foundations with high standards for quality governance and reproducibility.
  • Exceptional executive communication and stakeholder leadership with the ability to connect technical opportunities to scientific and organizational priorities.

Preferred Qualifications

  • Experience with AI-enabled experimentation laboratory automation or closed-loop optimization.
  • Familiarity with knowledge graphs ontologies semantic search and scientific data integration.
  • Experience connecting discovery data and insights with developability and downstream development needs.
  • A record of scientific publications intellectual property or impactful academic and industry collaborations.

Why Join Us

This is an opportunity to shape how Discovery Biologics invents new medicines of the future not simply how discovery data is analyzed in the largest health company on the planet.

You will bring scientific ambition and computational innovation together around a compelling purpose: helping scientists explore more possibilities learn faster and create better molecules for patients. Your influence will span strategy talent data foundations AI capabilities and the everyday decisions that move discovery forward.

If you are energized by deep science bold leadership and turning AIs potential into meaningful discovery impact we invite you to help us build the future of Discovery Biologics.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

#JRDDS

#JNJDataScience

JNJIMRND-DS

Required Skills:

Preferred Skills:

Advanced Analytics Budget Management Business Alignment Compliance Management Consulting Critical Thinking Data Analysis Data Privacy Standards Data Quality Data Reporting Data Savvy Data Science Data Visualization Developing Others Digital Fluency Inclusive Leadership Leadership Strategic Thinking

The anticipated base pay range for this position is :

$196000.00 - $342700.00

Additional Description for Pay Transparency:

Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Companys long-term incentive program.

Subject to the terms of their respective policies and date of hire employees are eligible for the following time off benefits:

Vacation 120 hours per calendar year

Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado 48 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year

Holiday pay including Floating Holidays 13 days per calendar year

Work Personal and Family Time - up to 40 hours per calendar year

Parental Leave 480 hours within one year of the birth/adoption/foster care of a child

Bereavement Leave 240 hours for an immediate family member: 40 hours for an extended family member per calendar year

Caregiver Leave 80 hours in a 52-week rolling period10 days

Volunteer Leave 32 hours per calendar year

Military Spouse Time-Off 80 hours per calendar year

For additional general information on Company benefits please go to: - Experience:

Exec

Vacancy posted 6 days ago
Similar jobs that could be interesting for youBased on the Sr Director R&D DDSAI Discovery Biologics in Spring House, PA vacancy
  •  ...Johnson & Johnson Innovative Medicine seeks a senior leader to oversee data and AI strategy for Discovery Biologics. The role focuses on translating computational advances into drug discovery practices, building multidisciplinary teams, and accelerating clinical candidate... 
    Senior

    Johnson & Johnson

    Spring House, PA
    6 days ago
  • $186.5k - $266.5k

    Job Title:Senior Director, R&D Management, Specialty ChemicalsJob Description:The RoleThe Head of Specialty Chemicals R&D will serve as...  ...Quality, Supply Chain, and Manufacturing to move molecules from discovery through qualification and commercial production.Strategic... 
    Senior
    Full time
    H1b
    Flexible hours

    Entegris

    Ambler, PA
    2 days ago
  • $117k - $201.25k

     ...Principal Scientist, Data Science – AI & Generative AI Systems – R&D DDSAI – Therapeutics Development & Supply (TDS). The primary...  ...work will directly accelerate Johnson & Johnson’s scientific discovery, fuel AI innovation, and impact patients globally. Johnson... 
    Suggested
    Full time
    Local area
    Immediate start
    Worldwide

    Johnson & Johnson Innovative Medicine

    Spring House, PA
    3 days ago
  •  ...Johnson seeks a Senior Machine Learning Engineer to build and operate ML/AI deployment and lifecycle management systems for biologics discovery. The role bridges model development and production environments, enabling AI solutions to scale reliably across scientific discovery... 
    Senior

    Johnson & Johnson

    Spring House, PA
    13 days ago
  • $164k - $282.9k

     ...Johnson & Johnson Innovative Medicine is recruiting for a Director, Physical AI for Autonomous Discovery to join our In Silico Drug Discovery team. The...  ...robotics, computer science, engineering, computational biology, or a related quantitative field. Demonstrated... 
    Suggested
    Full time
    Temporary work
    Local area
    Remote work

    Johnson & Johnson Innovative Medicine

    Spring House, PA
    3 days ago
  • $109k - $174.8k

     ...Johnson & Johnson seeks a Senior Ontologist to design and govern semantic models for biologics discovery data across antibodies, proteins, assays, and sequences. This cross-functional role transforms complex scientific terminology into reusable ontologies and controlled... 
    Senior

    Johnson & Johnson

    Spring House, PA
    29 days ago
  • $273.37k - $314.99k

     ...right time, in the right way.The Senior Director, Bioanalysis will provide strategic leadership...  ...Medicine, Regulatory, and other R&D functions to support program progressionContribute...  ...LC-MS/MS for quantitative bioanalysis in biological matrices is requiredDeep expertise in... 
    Senior
    Minimum wage
    Full time
    Local area
    Flexible hours

    Madrigal Pharmaceuticals

    Conshohocken, PA
    21 hours ago
  • $117k - $201.25k

     ...recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Pharmaceutical Product R&D Job Category: Scientific/Technology...  ...our In Silico Discovery (ISD), In Silico Biologics team. In this role, you will help shape the... 
    Full time
    Contract work
    Temporary work
    Local area
    Remote work

    Johnson & Johnson Innovative Medicine

    Spring House, PA
    3 days ago
  •  ...Johnson & Johnson in Horsham, PA, seeks a Senior Director to lead CAPA, escalation, and investigation programs across the organization....  ...global team, drive continuous quality improvement, and partner with R&D, Regulatory, and Operations to ensure robust quality systems.... 
    Senior

    6084-Janssen Research & Development, LLC Legal Entity

    Horsham, PA
    2 days ago
  •  ...Principal Scientist position in biologics optimization at Johnson & Johnson's Spring House, PA facility. Leads integration of experimental...  ..., and automation technologies to advance biologic drug discovery and establish design principles for molecule optimization.... 

    Johnson & Johnson

    Spring House, PA
    13 days ago
  • $178k - $307.05k

     ...124 Switzerland Req#: R-105123 Position Summary The Senior Director, CAPA and Escalations is responsible for developing and leading...  ...Management and Collaboration: Collaborate with internal stakeholders (R&D, Regulatory Affairs, Operations) to integrate quality processes... 
    Senior
    Temporary work
    Local area
    Immediate start

    6084-Janssen Research & Development, LLC Legal Entity

    Horsham, PA
    2 days ago
  • $231.9k - $365k

     ...Job Description The Executive Director, Organization & Talent Partner (OTP), Research & Development Division reports to the Vice President, Human Resources, Research & Development (R&D) Division and serves as the senior strategic organization and talent advisor to... 
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck

    West Point, PA
    3 days ago
  • $117k - $201.25k

     ...regulatory, quality, CMC, and scientific stakeholders to define use cases, validate outputs, and drive adoption Collaborate with DDSAI AI/ML teams on infrastructure, architecture, evaluation, and reusable components Requirements ~ Bachelor's degree in Engineering... 

    Johnson & Johnson

    Spring House, PA
    1 day ago
  •  ...recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: People Leader...  ...at are searching for the best talent for Director Omics Enabling Platforms in Spring House PA.... 
    Full time
    Local area

    Johnson & Johnson

    Spring House, PA
    6 days ago
  •  ...Johnson & Johnson seeks a Director to build and lead an Omics Enabling Platforms organization...  ..., robotics, and agentic AI for drug discovery. The role combines deep omics expertise...  ...platforms and translate high-dimensional biological data into actionable insights. Responsibilities... 

    Johnson & Johnson

    Spring House, PA
    13 days ago
  • $190.8k - $300.3k

     ...administration)Desired Experience and Skills:Expertise in Real-world evidence generation, advanced biostatistics and computational biology.Prior experience in digital pathology related analytics.Laboratory experience to understand how tissue is processed, including sample... 
    Full time
    For contractors
    Local area
    Visa sponsorship
    Flexible hours

    Merck Sharp & Dohme (MSD)

    North Wales, PA
    4 days ago
  •  ...Johnson & Johnson seeks an Associate Director to lead laboratory automation and intelligent orchestration platforms in drug discovery. The role combines strategic technology roadmap...  ...Lead cross-functional initiatives across biology, data science, and engineering... 

    Johnson & Johnson

    Spring House, PA
    10 days ago
  •  ...recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: People Leader...  ...searching for the best talent for Associate Director Expression Sciences in Spring House PA.... 
    Full time
    Local area

    Johnson & Johnson

    Spring House, PA
    6 days ago
  •  ...Merck seeks a Principal Scientist to lead sterile biologics drug product commercialization activities, including process development, scale-up, technology transfer, and regulatory submissions. The role requires deep expertise in late-stage manufacturing of large-molecule... 

    Merck

    West Point, PA
    5 days ago
  • $164k - $282.9k

     ...Johnson & Johnson seeks a Director to lead Physical AI strategy and build a team developing autonomous laboratory experimentation systems...  ..., robotics, and scientific reasoning to create self-improving discovery workflows that operate in real laboratory environments.... 

    Johnson & Johnson

    Spring House, PA
    1 day ago
  • $190.8k - $300.3k

     ...motivated Principal Scientist (Director) to serve as an Immunology...  ...connect drug mechanism, disease biology, precision medicine,...  ...biomarker strategies across discovery, early- and late-stage clinical...  ...experience. Autoimmune Diseases R&D and/or experience in translational... 
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    West Point, PA
    3 days ago
  •  ...Senior Director leading global CAPA, escalation, and quality issue management strategies across Johnson & Johnson's Innovative Medicine division. Oversees a 35-40 person team spanning Americas, Europe, and ASPAC regions, ensuring robust quality systems, regulatory compliance... 
    Senior

    Johnson & Johnson

    Horsham, PA
    3 days ago
  • $264k - $322k

     ...Madrigal Pharmaceuticals seeks a Senior Director of Biostatistics to lead statistical activities across clinical development phases for...  ...Oversee biostatisticians and programmers at company or CRO to execute R&D activities Conduct complex statistical analyses, develop... 
    Senior

    Madrigal Pharmaceuticals

    Conshohocken, PA
    13 days ago
  •  ...external innovation capability, and we're looking for a Senior Director of Search & Evaluation to help shape the future of our Immunology...  ...transactions.To be hybrid-based onsite (3 days a week) at one of our R&D hub sites: Zurich (CH), Maidenhead (UK), Waltham (US), King of... 
    Senior
    Full time
    3 days per week

    CSL

    King of Prussia, PA
    2 days ago
  •  ...Johnson & Johnson seeks two Principal Scientists for oncology discovery in Spring House, Pennsylvania. The role involves leading scientific...  ..., and manuscript writing Requirements Ph.D. in Cancer Biology or Immunology with 6+ years industry experience Demonstrated... 

    Johnson & Johnson

    Spring House, PA
    1 day ago
  • $173.2k - $272.6k

     ...group in West Point, Pennsylvania. The team primarily supports discovery programs across modalities (small molecules and conjugates)...  ...enabling strategic decisions from lead selection through FIH. As Director in the West Point DMPK group, your main responsibility is... 
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    West Point, PA
    21 hours ago
  • $173.2k - $272.6k

     ...talent to achieve exceptional results. The selected candidate will manage a team of ~10-12 scientists and manage a broad portfolio of Biologics, Antibody Drug Conjugate, and/or Vaccine programs. The leader will be expected to demonstrate subject matter expertise across... 
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    West Point, PA
    2 days ago
  • $117k - $201.25k

     ...Principal Scientist role in AI-native biologics discovery within Johnson & Johnson's In Silico Drug Discovery team. The position integrates artificial intelligence, computational design, and predictive modeling into therapeutic discovery programs across three U.S. locations... 

    Johnson & Johnson

    Spring House, PA
    1 day ago
  • $210.4k - $331.1k

     ...Senior Director position leading field-based medical professionals in oncology at a pharmaceutical company. Responsibilities include team management, performance oversight, disease state support plan execution, and regional budget management while ensuring regulatory... 
    Senior

    Merck

    Upper Gwynedd, PA
    10 days ago
  • $273.37k - $314.99k

     ...Madrigal Pharmaceuticals seeks a Senior Director of Bioanalysis to lead bioanalytical strategy and oversight across clinical and nonclinical...  ...LC-MS/MS expertise for quantitative bioanalysis in biological matrices ~ Deep knowledge of bioanalytical assay development... 
    Senior

    Madrigal Pharmaceuticals

    Conshohocken, PA
    13 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Sr Director R&D DDSAI Discovery Biologics. Be the first to apply!