Scientist / Sr Scientist - Therapeutic Discovery (Protein Engineering)

Scientist / Sr Scientist – Therapeutic Discovery (Protein Engineering) 3T Biosciences is solving a major bottleneck in the field of immunotherapy – identifying novel targets that can be used to generate therapies to treat cancer in broad patient populations. We are developing transformative T cell receptor therapies for cancer and other immune-related diseases. Our proprietary experimental and computational technology allows us to identify novel T cell receptor targets as well as clinical toxicities to develop safe and effective therapies. Your Typical Responsibilities: Design, execute, and manage antibody lead discovery and optimization against novel peptide-HLA targets using yeast display Lead antibody bi/multispecific design, screening, and characterization to support development candidate nomination against peptide-HLA targets Peptide-HLA binding specificity determination using proprietary yeast display peptide libraries Molecular cloning of antibodies & bispecifics for recombinant expression Mentor RA/SRAs to support company projects Work in a matrixed team environment, routinely collaborating with Protein Science and Biology groups Required Qualifications: Doctoral (PhD) degree and 2-6 years relevant industry experience in immuno‑oncology and bispecific therapies Experience with yeast display antibody engineering Experience with SPR for antibody/bispecific affinity measurement Experience in designing and generating libraries for antibody optimization Experience in molecular biology techniques Ability to work independently to design, execute, interpret, and troubleshoot experiments A team player with excellent verbal and written communication skills, highly organized, and able to thrive in a fast‑paced environment The annual salary range for this position is $140,000 USD to $160,000 USD. This salary range is an estimate of what we reasonably expect to pay for this posted position and the actual salary may vary based on various factors, including without limitation individual education, experience, tenure, skills and abilities, as well as internal equity and alignment with market data. This position is also eligible for annual performance bonus, benefits, paid time off and participation in company stock options. 3T Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. 3T is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non‑disqualifying physical or mental disability, national origin, veteran status or any other legally protected status. #J-18808-Ljbffr 3T Biosciences, Inc.