Executive Director, Global Program Lead, Early Development Oncology - Targeted Therapies
$286.31k - $346.95kBristol Myers Squibb
Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Position Summary Global Program Leads at BMS are strategic-thinking, problem-solving, and action oriented business leaders who bring drug development and commercialization insights to drive a sustainable pipeline of innovative medicines. GPLs serve as the “point of accountability” for their assets and are respected, matrix leaders, overseeing multi-disciplinary teams typically responsible for the development of assets from later stage Discovery (pre-GT2) through commercialization. They will foster a high performing, highly collaborative, play to win team environment aimed at developing and implementing compelling, integrated asset strategies to achieve ambitious near- and long-term portfolio objectives. Each leader is accountable to therapeutic area, R&D, commercial and Company Leadership for: (i) creating a vision and defining the strategy and integrated development plan for each asset within their portfolio, (ii) developing a set of objective criteria against which each asset advancing through the pipeline will be evaluated to enable robust debate and rapid, data-driven decision making; and (iii) ensuring that only high quality and differentiated assets enter the market. Key Responsibilities Strategy and Execution Uses an understanding of disease biology, the drug development process (particularly cross-functional connectivity), and relevant late-stage challenges (e.g., trends in disease area therapeutic advances, and evolving regulatory, patient advocacy and market access environments) to create a vision for each asset, then design and execute effective development programs in support of the overall R&D portfolio goals. Effectively engages cross company expertise and utilizes advisory groups and governance bodies to define, revise and champion asset development strategies and implementation plans. Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving toward delivering key data and interpretation essential for robust debate and rapid, data-driven decision making on assigned projects. Delivers high quality assets to commercial which have the potential for a competitive profile to address the unmet medical needs of patients and to provide favorable shareholder return. Ensures the process and output of the team meets established program standards (per PD&C Process expectations, within budget, on schedule, compliant, etc.), while also looking for opportunities to streamline development and enable continuous improvements without compromising quality. Engages senior leaders and functional area stakeholders to ensure alignment of program strategy and operational plans with functional area capabilities, and clearly communicates program risks, implications of changes in the competitive landscape and progress toward key milestones. Actively provides input to and drives portfolio level strategy for both internal and external opportunities. Participates in regulatory filings (NDA, BLA filings) as well as develops strategy for orphan drug designation. Engages with Health Authorities and/or Advisory Committees in the design of clinical trials and endpoints. Leads team to develop program strategy and clinical program, commercialization strategy plans, business case development, and understands how access, pricing and reimbursement needs for supporting value proposition will inform trial design. Builds and maintains collaborative relationships with external stakeholders (Opinion Leaders, Strategic Alliance Partners, Patient Advocacy Leaders, Health Authorities) and appropriately incorporates insights and advice to maximize program impact. Understands clinical trial operational complexities from study start up through enrollment, quality assurance, and study readout. Has an active role in analysis and/or interpretation of clinical data and translation into scientific communication strategy, including publications, and commercial strategy. Understands and reflects the impact of VAP inputs (Early Access Review and DEX recommendations, commercial opportunity assessment, TOP / TPP requirements, and value drivers as inputs in clinical trial design. Actively supports Investor Relations and Public Affairs in managing external BMS communications. Integrates commercialization inputs and deliverables to design the late program strategy that enables approval of a meaningfully differentiated asset with potential to maximize asset value. Understands necessary commercial inputs needed to inform the end-to-end development process leading to regulatory approval and successful commercialization. Integrates market inputs (e.g., TPP, DEX/VAP, CI insights) into the integrated development plan, including, clinical plans and labeling strategy; Appreciates translation of clinical data into claims and considerations for label development. Understands and contributes to development of forecasts and investment scenarios, how to assess risk and conduct valuations, and implications for decision-making. Contributes to the development of brand hallmarks and brand strategy (generic name, brand name, logo, brand colors, positioning, messaging, campaign, segmentation, promotional strategy) understanding the relationship to clinical trial design. In partnership with Medical Affairs, supports development of KOL plans and engagements, and leverages KOL input in context of development programs and communicating evidence. Supports commercial needs and recommendations to guide CMC and GPS on trade packaging and commercial product. Leadership and Matrix Alignment Inclusively Collaborates Across the BMS Matrix with an Enterprise Mindset: Effectively collaborates with matrix functions by building trust and driving toward the collective success of the program Demonstrates Enterprise Mindset Problem-Solving and Decision Making: Gathers diverse perspectives assess alternate resolutions and makes thoughtful, informed Enterprise decisions Develops and Leads a High Performing Matrix Team: Builds, leads and inspires high performing cross functional matrix team through a unified program strategy on behalf of our patients Holds Oneself and Others Accountable: Takes initiative to address challenges, removes barriers, holds others accountable for the collective success of the program outcomes and team collaboration Demonstrates Character: Leads with integrity & the values of self-awareness & humility and seeks feedback Qualifications & Experience MD, PhD, DVM, PharmD, MBA or equivalent advanced degree of relevance, with experience in the drug development process. 10+ years of experience in the drug development process and leadership experience in academic or industry setting, including education where applicable. Expertise in the drug development process with in-depth know how and experience in matrix team leadership, relevant regulatory expectations, and overall drug development and commercialization. Successful track record of leading through influence and working across complex, global organizational matrix. Significant experience in cell therapy preferred, with demonstrated understanding of the role of basic biology, pharmaceutical optimization, translational medicine, and clinical pharmacology, including exposure-response relationships and dose selection. Strong understanding of relevant regulatory health authority expectations and regulations for drug development and impact on commercialization. Working knowledge of all functional areas of exploratory development, including chemistry/biochemistry, biology, toxicology, CMC, translational medicine, early clinical development, etc. Demonstrated scientific acumen and mechanistic understanding of pharmacology and disease biology. Ability to create a clear purpose, global vision, strategies and key priorities for competing successfully in the evolving pharmaceutical and health care industry. Demonstrated ability to lead cross-functional team to execute Development Plans which have global perspective and focus on product differentiation, including opportunities for data driven acceleration. Demonstrated ability to objectively assess complex but relatively sparse data sets, make informed decisions and take action in the face of uncertainty. Demonstrated ability to present complex programs to senior leaders and influence decision making. Experience in successfully managing and leading high performing, cross-functional matrix teams or complex multi-functional organizations. Demonstrated ability to coach and mentor others to enhance performance and/or facilitate career progression. Ability to effectively and seamlessly multi-task, and prioritize across multiple development assets, with complex strategies and accelerated development timelines. Demonstrated ability to successfully and effectively cooperate, collaborate and work across functions. Demonstrated ability to advise and participate in business development due-diligence evaluations and transaction recommendations. If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: $286,310 - $346,945 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. *Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to View email address on click.appcast.io. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Candidate Rights BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at View email address on click.appcast.io. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email a
$164k - $205k
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$164k - $205k
...stage clinical oncology company developing novel targeted therapies for patients... ...currently in clinical development. As a new... ...designated program budgets. Partner... ...ability to lead and manage multiple... ...Study Execution Team (CSETs) and... ...Oncology experience, early and/or late...SuggestedFull timeContract workTemporary workWork at office$265k - $331k
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...precision medicine oncology company... ...discovery, development, and... ...transformative therapies for cancer.... ...first‑in‑class targeted therapies aligned... ...operational lead and subject‑... ...for ICSR execution across the development... ...by the Director of Safety... ...across programs and vendors....Temporary workLocal area$399.6k - $427.5k
...platform of novel therapies for people... ...approach targets upstream C1q... ...President, Clinical Development-Neuroscience.... ...strategy and execution of the portfolio of programs in... ...functional teams, lead clinical aspects... ..., from early-phase through... ...alignment with global regulatory guidelines...Remote workFlexible hours$265k - $331k
...‑stage clinical oncology company developing novel targeted therapies for patients with... .... Opportunity Executive Director of GCP QA is a senior... ...executes the global GCP quality... ...across clinical development programs. The role ensures... ...QA activities, leads a high‑performing...Full timeContract work$146.54k - $189.64k
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...Executive Director, Clinical Quality Assurance Boston... ...best‑in‑class therapies that address... ...diseases. Jade’s lead candidate, JADE101, targets the cytokine... ...in preclinical development. Jade was launched... ...our clinical programs in addition to... ...Stay current on global regulations, industry...Work at officeRemote work- ...the lack of new therapies resulting from... ...drug development model, that has... ...accelerate better, targeted treatments so... ...The RWE/HEOR Lead will work alongside... ...the Senior Director, Evidence Generation... ...generation programs that advance... ...strategy and execution and will assist...Contract work
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...first-in-class therapies to address genetically... ...disease targets. Our therapies... ...a syndicate of leading life science investors... ...company’s lead program, MAR001, is a... ...2b clinical development. Our second... ...second program into early-stage clinical... ..., develop and execute life cycle plans...Local area- ...including immunology, oncology and neuroscience -... ...Purpose Leads the direction, planning, execution, and interpretation... ...or more clinical development programs, with principal responsibility... ...and/or Scientific Directors and of Clinical... ...studies and global drug development and...Local area
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...discovery and development of novel... ...therapeutics to target this... ...Ventures, a leading healthcare venture... ...the Senior Director, Clinical Operations... ...'s clinical programs with... ...portfolio are executed on time,... ...5+ years of global clinical operations... ...teams. ~ Oncology or rare...Full time3 days per week$225k - $250k
...Director, Clinical Operations... ...the industry-leading G protein-coupled... ...of GPCR-targeted small molecule programs with potential... ...committed to the development of... ...directly help move therapies through... ...strategic planning, execution, and... ...patient-facing, global studies) in...Full timeContract work- ...the discovery, development and... ...small molecule therapies designed to modulate... ...drug candidates targeting E3 ligases, a... ...progressing multiple programs through... ...Reporting to the Director, Regulatory... ...authorities (US FDA and global equivalents).... ...tracking and execution of submissions...
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