Associate Director, Chemical Engineering
Nurix Therapeutics
Nurix Therapeutics seeks an Associate Director of Chemical Engineering to lead end-to-end chemical engineering support for bexobrutideg drug substance from late-stage development through commercial launch. The role involves oversight of contract manufacturing organizations, process optimization, technology transfer, and regulatory strategy for a targeted protein degradation therapeutic.
Responsibilities
- Design, develop, and optimize scalable routes for small-molecule drug substance manufacturing
- Oversee equipment engineering and scale-up operations at external manufacturing sites with hands-on troubleshooting
- Lead technology transfer and process demonstration to contract manufacturers
- Review and approve batch records, campaign reports, and change controls for drug substance operations
- Author and review CMC regulatory sections for INDs and NDAs, including responses to health authority queries
Requirements
- Advanced degree in chemical engineering or related discipline
- Demonstrated expertise in small-molecule drug substance manufacturing and scale-up
- Strong knowledge of unit operations, process modeling, and equipment selection
- Experience with contract development and manufacturing organizations (CDMOs)
- Familiarity with FDA, EMA, ICH, and cGMP regulatory standards
- Track record of leading cross-functional teams and regulatory submissions
- Nurix Therapeutics is seeking an experienced Associate Director, Chemical Engineering to lead end‑to‑end DS manufacturing support for bexobrutideg (NX-5948) from late-stage development through commercial launch, including oversight of CDMOs. The Associate Director will...Suggested
$189.8k - $216.7k
...Powered by a fully AI-integrated discovery engine capable of tackling any protein class,... ...who will be accountable for end‑to‑end chemical engineering support of bexobrutideg (NX... ...of external manufacturing sites. The Associate Director, Chemical Engineering will work closely...SuggestedContract work$142.4k - $224.1k
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