Research Associate II - Cutaneous Lymphoma

Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Research Associate II will work under the supervision of the Principal Investigator to help establish and operate a basic science/translational research laboratory focused on cutaneous lymphoma biology at City of Hope. This individual will perform molecular biology experiments, manage laboratory workflows, maintain supplies/equipment, and help generate high-quality datasets for downstream analyses.

As a successful candidate, you will:

Molecular Biology & Sequencing

• Perform molecular biology techniques including DNA/RNA extraction, PCR, qPCR, gel electrophoresis, and nucleic acid quantification.

• Conduct next-generation sequencing library preparation (DNA, RNA, or targeted panels) following established protocols.

• Assist with sample preparation for single-cell sequencing, proteomic assays, or spatial profiling as the lab develops.

• Process patient-derived biospecimens (blood, tissue, PBMCs, skin biopsies) following IRB and biosafety protocols.

Laboratory Operations & Equipment

• Operate, maintain, and troubleshoot laboratory equipment, including thermal cyclers, centrifuges, biosafety hoods, sequencers, microscopes, and flow cytometers.

• Prepare solutions, reagents, buffers, stains, and media according to standard laboratory formulas.

• Track inventory levels, order supplies, and ensure an efficiently functioning laboratory environment.

Experimental Design & Data Handling

• Assist in planning experiments, optimizing protocols, and interpreting results in collaboration with the PI.

• Maintain accurate electronic laboratory notebooks, sample logs, and project documentation.

• Perform basic computational analysis (e.g., qPCR data analysis, gel quantification, flow cytometry gating) with opportunities to advance in bioinformatics.

Collaboration & Translational Support

• Interface with the clinical team to coordinate transfer and tracking of patient samples from the cutaneous lymphoma cohort.

• Ensure chain-of-custody documentation for samples entering the laboratory.

• Participate in multidisciplinary translational research meetings.

Your qualifications should include:

• Bachelor’s degree. Master’s degree preferred.

• Two years related research/ laboratory experience with a Bachelor’s degree or one year related research/ laboratory experience with a Master’s degree.

Preferred qualifications:

• Hands-on experience with core molecular biology techniques.

• Prior experience with sequencing library preparation, PCR optimization, or advanced molecular techniques.

• Experience in dermatology, immunology, cancer biology, or related research.

• Familiarity with R, Python, or Linux in a bioinformatics context.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE .