Sr. Manager, Global Demand Planning

Overview Senior Manager, Global Planning is a key member of the Global Supply Planning Organization and is responsible for ensuring uninterrupted supply to all Alnylam patients both late-stage clinical and commercial, in line with corporate and program objectives. The position entails building strong cross-functional relationships throughout the organization, understanding overall program risk, providing scenario planning and generating an achievable production plans. The position is also a key contributor to the Global Sales & Operations Planning (S&OP) process, helping to develop and mature related systems and processes. The successful candidate brings strong S&OP expertise, experience managing transfer of products from clinical to commercial phase with the associated launch, global supply planning, implemented and maintained ERP systems and has a clear understanding of late-stage development timelines and challenges. This is a hybrid position based in our Cambridge, Massachusetts office. Responsibilities Collect and understand demand-planning assumptions by working closely with Finance, Commercial, Clinical Supply, and Program Teams, with particular focus on clinical and commercial milestones. Maintain a holistic understanding of the demand and supply dynamics affecting assigned program(s), with the ability to process data, identify problematic areas and propose solutions in conjunction with cross-functional team. Manage the Commercial Supply planning process, this includes but not limited to, development of global finished goods packaging plans, global inventory management, and launch planning. Develop annual long-range manufacturing plans based on available information and clearly communicate constraints and risks. Partner with Commercial teams, Finance, internal and external manufacturing, Quality Assurance, Global Logistics, and IT to ensure material availability aligns with commercial timelines and budget. Segregate and allocate inventory versions to mitigate supply risk and ensure compliance with respective countries regulatory approval timelines. Serve as a key contributor to the monthly Commercial S&OP meeting. Facilitate Regional S&OP reviews in conjunction with Global S&OP process Partner cross-functionally to develop scenario plans and strategies that translate into production plans meeting program, capacity, and budget requirements. Lead Supply Chain Continuous Improvement Projects. Engage partners to make and sustain changes. Qualifications Bachelor's degree in Business, Supply Chain, Engineering, or a science-related discipline (Masters Degree is a plus) Minimum 7 years of relevant experience in a Supply Chain Planning role, preferably in a Biotechnology or Pharmaceutical environment Strong knowledge of advanced planning and scheduling systems: SAP IBP, Kinaxis or similar tools High level of proficiency in Excel, Data Analysis and Modelling Experience with site capacity planning and/or global product supply planning and knowledge of Biotech, Pharmaceutical Sales & Operations Planning processes Excellent communication skills, with the ability to influence and present complex information to diverse audiences and levels of the organization U.S. Pay Range $136,900.00 - $185,200.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. About Alnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. #J-18808-Ljbffr