Oncology Medical Science Liaison Manager (Regional)

Job Description

Job Description

Oncology MSL Manager

Natera is a clinical genetic testing company using our proprietary cell-free DNA (cfDNA) platform to help oncology patients make earlier, better-informed decisions. As an Oncology MSL Manager, you will lead a regional team of field-based Medical Science Liaisons (MSLs) focused on scientific engagement for Signatera, our personalized, tumor-informed minimal residual disease (MRD) test. This role requires a blend of scientific rigor and operational urgency to help clinicians change the management of disease worldwide.

The Manager operates with a high degree of ownership, translating strategy into clear direction for the field team while partnering cross-functionally to support Natera's oncology diagnostics. This role is accountable for team performance, field execution, and alignment with Medical Affairs priorities. The MSL Manager ensures MSLs are effectively engaging healthcare providers, generating actionable insights, and delivering accurate genetic testing insights to clinicians when timing matters most for patient outcomes.

PRIMARY RESPONSIBILITIES

People Leadership & Development

• Lead, develop, and manage a regional team of MSLs, with clear accountability for performance and results.

• Provide consistent coaching through regular 1:1s, field co-travel, and structured performance feedback.

• Own onboarding, training, and ongoing development of MSL team members.

• Assess individual performance and implement development or corrective action plans as needed.

• Support team engagement, retention, and ongoing professional development.

Field Execution & Territory Oversight

• Ensure consistent, high-quality scientific engagement across the region aligned to Medical Affairs priorities.

• Maintain strong visibility into regional activities, key accounts, and KOL engagement.

• Ensure appropriate field coverage to support clinical engagement, commercial team alignment, and educational initiatives.

• Guide MSLs in prioritizing field activities and managing competing stakeholder demands.

• Act as a resource for MSLs on complex or high-stakes field engagements.

Cross-Functional Alignment

• Collaborate cross-functionally with commercial and regional leadership to ensure everyone pulls in the same direction for patient care while maintaining scientific integrity.

• Support MSLs in building strong, collaborative relationships with regional and area stakeholders.

• Participate in cross-functional planning and collaboration with Medical Affairs leadership and regional teams.

• Ensure effective communication and alignment between field activities and organizational priorities.

Performance & Insights

• Use data and field insights to keep the team accountable, moving fast, and focused on patient impact.

• Drive accountability for documentation, insights, and engagement quality across the team.

• Aggregate and communicate key field insights, including clinical trends, competitive dynamics, and unmet needs.

• Identify performance gaps and implement targeted improvements across the team.

Additional Responsibilities

• Maintain proficiency in the role of an MSL, including the ability to support scientific discussions as needed.

• Travel up to 40% for field engagement, co-travel, and conferences.

• Adapt quickly to emerging field and clinical needs to support the oncology portfolio.

QUALIFICATIONS

• Advanced scientific or healthcare degree required (PhD, PharmD, MD, or equivalent)

• 4–8+ years of Medical Affairs or MSL experience

• Prior experience managing or leading teams strongly preferred

• Demonstrated success operating in a field-based, cross-functional environment

• Must reside within assigned region

KNOWLEDGE, SKILLS, AND ABILITIES

• Proven ability to lead and develop field-based teams, driving performance and accountability

• Strong ability to translate strategy into clear direction and execution for field teams

• Demonstrated ability to manage performance using data, metrics, and field insights

• Strong cross-functional collaboration skills, particularly with Commercial, Marketing, and Clinical teams

• Thrive and lead without rigid structure, operating with a sense of urgency to solve problems and advance clinical adoption

• Strong problem-solving skills and ability to address complex field challenges

• Excellent communication skills, including the ability to convey complex scientific information clearly

• High level of independence, accountability, and sound judgment

PHYSICAL DEMANDS & WORK ENVIRONMENT

• This is a remote position, and often work requires frequent sitting, standing, and walking. Daily use of a computer is required. May stand for extended periods when facilitating meetings or walking long distances. Ability to travel is required.

• This position requires the ability to use a computer keyboard, communicate over the telephone, and read printed material.

• Duties may require working outside normal working hours (evenings and weekends) based on field flexibility needs.

• Employees must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training, and security training within the first 30 days of hire.

• Must maintain current status on Natera training requirements.

• Reasonable accommodation is available for individuals with disabilities to perform essential job functions.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$200,000—$220,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: -of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page