Business Systems Analyst, SharePoint & Collaboration Platforms

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.


What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.


Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.


Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.

Business Systems Analyst - SharePoint & Collaboration Platforms

Job Summary

The Business Systems Analyst (BSA) - SharePoint & Collaboration Platforms is responsible for the administration, optimization, and strategic enablement of Flagship Pioneering's knowledge management and collaboration ecosystem, with a primary focus on SharePoint as the enterprise knowledge platform.

This role combines hands-on SharePoint administration with broader collaboration tooling support (e.g., Slack, Notion, Smartsheet), ensuring systems are well-governed, user-friendly, and aligned with evolving business needs. The BSA serves as a subject matter expert for SharePoint, driving adoption, improving knowledge structures, and enabling scalable, efficient ways of working across the organization.


Key Responsibilities

SharePoint Administration & Knowledge Management

• Administer, configure, and maintain SharePoint Online environment, ensuring performance, security, and reliability.
• Design and manage site architecture, libraries, lists, metadata, and content types to support scalable knowledge management.
• Establish and enforce governance standards, permissions models, and content lifecycle policies.
• Develop and optimize knowledge structures (hubs, document management frameworks).
• Troubleshoot and resolve issues related to access, performance, integrations, and usability.
• Serve as the primary subject matter expert (SME) for SharePoint across the organization.

Collaboration Platform Management

• Administer and support tools such as Slack, Notion, Smartsheet, and other collaboration applications.
• Partner with teams to design workspaces, templates, and workflows that improve usability and adoption.
• Monitor system usage and optimize licensing, performance, and configuration.
• Maintain system documentation, runbooks, and governance guidelines.

Workflow Automation & Integration

• Design and implement workflows using Power Automate and other automation tools.
• Support integrations across Microsoft 365 and third-party platforms.
• Identify opportunities to streamline collaboration and knowledge-sharing processes through automation.

User Enablement & Adoption

• Lead onboarding, training, and support for SharePoint and collaboration tools.
• Promote best practices for knowledge organization, content management, and collaboration.
• Act as a trusted advisor to business teams on how to effectively leverage SharePoint as a knowledge platform.

Continuous Improvement & Projects

• Identify and drive improvements in knowledge management, collaboration, and productivity.
• Support implementation of new tools, enhancements, and migrations (e.g., SharePoint modernization).
• Collaborate with IT, security, and business stakeholders to ensure solutions meet technical and business requirements.

Key Skills & Competencies

• Deep expertise in SharePoint Online (architecture, governance, administration).
• Strong understanding of knowledge management principles and content organization.
• Experience with Microsoft 365 ecosystem (Teams, OneDrive, Power Platform).
• Ability to balance governance with flexibility and user experience.
• Strong problem-solving, troubleshooting, and analytical skills.
• Excellent stakeholder engagement and communication abilities.

Education & Experience

• Bachelor's degree in Information Systems, Business, Computer Science, or related field (or equivalent experience).
• 3-5+ years of SharePoint administration experience in enterprise environments.
• Experience supporting collaboration platforms (e.g., Slack, Notion, Smartsheet) preferred.
• Hands-on experience with:
• SharePoint site architecture, permissions, and governance
• Power Automate / Power Platform
• Workflow design and system configuration
• Experience with migrations, integrations, or enterprise application support is a plus.

We are an equal opportunity employer . All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.


We recognize that great candidates often bring unique strengths without fulfilling every qualification . If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.


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The salary range for this role is $76,000 - $104,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact View email address on click.appcast.io.