Sr. Process Engineer

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you'll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact-on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio:

Summary

RayzeBio is seeking an experienced Senior Process Engineer to drive technical excellence and mentor team members in our rapidly expanding radiopharmaceutical operations. As our business continues to grow and scale, this role will be pivotal in leading initiatives that enhance hot cell and radioisotope production/purification processes, supporting both clinical and commercial expansion.

The successful candidate will provide engineering expertise to evaluate, select, and startup critical equipment in a new facility. This will include troubleshooting and problem solving across multiple areas as you work cross-functionally with Radiochemistry, Health Physics, and Production teams to evaluate, transfer, and scale cutting-edge radiopharmaceutical technologies, supporting the organization's strategic growth trajectory.

This position offers the unique opportunity to lead transformative projects that directly impact RayzeBio's continued growth and leadership in the industry.

As a technical leader, you will champion the integration of advanced solutions, oversee optimization efforts, and help build a robust infrastructure to support increased production capacity and business expansion.

Job Responsibilities

Essential duties and responsibilities include the following. Other duties may be assigned.

• Provide technical leadership and expertise across radiopharmaceutical production, process development, and facility operations, supporting strategic expansion and innovation.

• Guide the evaluation, selection, commissioning, and optimization of critical production and purification equipment within the new facility.

• Lead troubleshooting and problem resolution efforts, collaborating with multidisciplinary teams to deliver effective solutions in a dynamic manufacturing environment.

• Identify and drive process improvements and technology enhancements to increase operational efficiency, reliability, and safety.

• Oversee the development and approval of technical documentation to ensure compliance with regulatory standards and best practices.

• Analyze process data and trends to advise on opportunities for quality and throughput enhancements as RayzeBio scales its operations.

• Build and foster collaborative relationships with internal stakeholders and external partners to support business growth and transformation.

• Provide mentorship, training, and thought leadership to engineering, operations, and technical staff; promote a culture of continuous improvement and excellence.

• Support the implementation and integration of new technologies and automation solutions in alignment with business objectives.

• Maintain current knowledge of industry advancements, proactively recommending and implementing improvements to maintain RayzeBio's leadership position.

• Champion safety and regulatory compliance throughout all engineering activities.

• May require up to 15% travel for project support and provide guidance during off-hours for critical needs.

• Provide guidance and support during off-hours for critical equipment emergencies.

Education and Experience

· Bachelor's degree in Chemical Engineering, Nuclear Engineering, Mechanical Engineering, or related discipline (Master's or PhD preferred).

· 7+ years of experience in radiopharmaceuticals, pharmaceuticals, or regulated manufacturing environments.

· Hands-on experience with particle accelerator operation and maintenance a plus.

· Advanced knowledge of hot cell systems, radiation safety protocols, and radioisotope handling.

· Expertise in purification methods, analytical instrumentation, and material transfer in controlled environments.

· Comprehensive knowledge of OSHA/NRC regulations and thorough understanding of cGMP, GDP, and FDA requirements applicable to radiopharmaceutical processing.

· Proven ability to lead projects and teams within a radiation-controlled environment.

Skills and Qualification

• Recognized technical leader with excellent mentoring, interpersonal, and cross-functional collaboration skills.

• Demonstrated expertise in project management, process improvement, and change leadership.

• Advanced written and verbal communication skills, including technical writing, report preparation, and presentation abilities.

• Strong analytical skills with acute attention to detail and strategic problem-solving capabilities.

• Ability to interpret and validate complex technical drawings, schematics, and manuals.

• Champions a "can-do" attitude, fostering a culture of innovation, adaptability, and responsiveness within the team.

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Physical Demands

• While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision and distance vision

Work Environment

• The noise level in the work environment is usually moderate.

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If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Indianapolis - RayzeBio - IN: $124,449 - $150,803

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

? Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to View email address on click.appcast.io . Visit careers.bms.com/ ( eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Data Protection

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Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at View email address on click.appcast.io . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.

R1599441 : Sr. Process Engineer Company: BMS

Req Number: R1599441

Updated: 2026-06-02 01:44:31.864 UTC

Location: Indianapolis-IN

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.