Sr. Director, Sales Operations & Commercial Excellence (United States)

Company Background:

Cerenome (Nasdaq: CNSY) is a clinical-stage central nervous system (CNS) oncology company focused on transforming how rare and severe brain and spinal cancers are diagnosed, monitored, and treated. Our work brings together advanced diagnostics, targeted radiotherapeutics, and data analytics to address some of the most difficult challenges in neuro-oncology.

Our portfolio includes CNSide®, our proprietary cerebrospinal fluid-based diagnostic platform designed to support the diagnosis and management of cancers involving the central nervous system, and REYOBIQ™, our investigational radiotherapeutic currently in clinical development.

As we grow, many of the systems, capabilities, and ways of working that will support our next stage are being built now. We see that as an opportunity—and we're looking for people who do, too.

Role:

Cerenome is looking for a Senior Director, Sales Operations & Commercial Excellence to help build the commercial infrastructure supporting our CNSide Diagnostics business and its next stage of growth. This is a builder role. You'll work closely with our Vice President, Commercial Sales and other leaders to establish the commercial foundation for our next stage, beginning with two immediate priorities: territory design and sales incentive compensation.

As our commercial organization grows, you'll help shape how we structure territories and accounts, measure performance, leverage commercial data, manage our CRM, forecast the business, and build scalable operating processes. We're looking for someone with demonstrated experience building commercial infrastructure who can operate at both the strategic and tactical levels—setting strategy and advising senior leaders while also rolling up their sleeves to build the models, processes, and tools that bring those decisions to life.

As our commercial organization grows, this role is expected to evolve and may eventually include responsibility for building and leading a Sales Operations/Commercial Excellence team.

Responsibilities:

• Develop and evolve the territory and account model for our growing field organization, including territory architecture, account segmentation, targeting, coverage, capacity, and resource allocation.
• Partner with Commercial Leadership, Finance, and HR to design sales incentive compensation plans that reinforce appropriate commercial behaviors and business outcomes.
• Build the quota structures, performance measures, payout mechanics, and modeling needed to administer and evaluate incentive compensation plans effectively.
• Establish HubSpot as a reliable and disciplined source of commercial information, including appropriate data structure, workflows, pipeline management, reporting, and governance.
• Build commercial data and CRM infrastructure with an eye toward what Cerenome may require as the commercial organization becomes larger and more complex.
• Develop practical dashboards, forecasts, KPIs, and reporting that provide Commercial Leadership and the Executive Management Committee with meaningful visibility into performance, productivity, opportunities, and emerging risks.
• Establish scalable commercial operating rhythms, workflows, processes, and governance to support a growing sales organization.
• Identify opportunities to simplify and automate commercial processes as the organization grows.
• Partner across Commercial, Marketing, Finance, HR, and other functions on commercial planning, sales capacity, organizational growth, and related initiatives.
• Help determine when existing commercial infrastructure needs to evolve and identify additional capabilities required to support continued growth.

Qualifications:

• Significant experience in Sales Operations, Commercial Excellence, Revenue Operations, Commercial Analytics, or a closely related discipline, ideally within diagnostics, biopharma, laboratory services, life sciences, healthcare, or another complex commercial environment.
• Demonstrated experience building commercial infrastructure, not simply managing an established function.
• Experience designing or substantially building territory and account models and sales incentive compensation programs.
• Strong knowledge of sales planning, quota setting, forecasting, pipeline management, performance measurement, and commercial analytics.
• Hands-on CRM experience, including data structure, workflows, reporting, dashboards, and governance. Our current commercial platform is HubSpot.
• Strong analytical capabilities and the ability to turn imperfect or disparate data into actionable business insights.
• Experience developing practical dashboards, forecasting models, and executive-level commercial reporting.
• Ability to work effectively across Commercial, Finance, Marketing, HR, and other functions where priorities and perspectives may differ.
• Strong judgment and communication skills, including the ability to advise senior leaders, challenge assumptions when appropriate, and translate decisions into practical execution.
• Experience in oncology, molecular diagnostics, precision medicine, or laboratory services is highly valued.
• Experience supporting the commercialization of a new product or emerging technology and/or building Sales Operations capabilities during significant organizational growth is preferred.
• Advanced HubSpot or Salesforce experience, including CRM implementation or migration, is preferred.
• Experience integrating commercial, marketing, financial, or other business data is preferred.
• Technical experience with data, analytics, APIs, or related tools is valuable; however, we are more interested in what you've been able to build and enable with technology than in a particular list of technical credentials.
• Bachelor's degree or equivalent combination of education and relevant experience.

Requirements:

• Ability to operate effectively at both strategic and tactical levels in a growing organization.
• Strong analytical, organizational, problem-solving, and communication skills.
• Ability to work effectively in a fast-paced environment with evolving priorities.
• Ability to collaborate cross-functionally and influence stakeholders at multiple levels of the organization.
• Ability to work effectively in a remote or hybrid environment.
• Ability to travel approximately 15–25%, based on business needs.

Position Details:

Reports to: Vice President, Commercial Sales

Employment Type: Full-time

Location: Remote or Hybrid

Travel: Approximately 15–25%, based on business needs

Cerenome is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, veteran status, or any other characteristic protected by federal, state, or local law.