Principal Scientist / Associate Director - Translational Biology

Job Description

Job Description

About Dualitas Therapeutics  

At Dualitas Therapeutics, we are redefining bispecific antibody discovery and development for autoimmune disease. Based in South San Francisco, California, our scientists are pioneering innovative technology to advance the next generation of antibody therapeutics. Our employees are our most important asset, and together we are dedicated to making Dualitas a scientifically superb and highly collegial place to work.

Position Summary

We are seeking a highly motivated and experienced Principal Scientist / Associate Director to join our Translational Biology team. The successful candidate will report to the Senior Director of Translational Biology. The incumbent will have hands on experience leading research programs and will be skilled in developing and executing experiments to advance novel biologics. This role will have the opportunity to lead programs from early discovery to IND-enabling studies, working collaboratively across groups in research and development and will be the scientific team leader responsible for data analysis, thorough documentation in advancement of INDs, and clear communication of results.

Key Responsibilities

• Lead research programs and work collaboratively with researchers and management to define strategic direction and execute on programs 

• Design and implement critical experiments to advance programs into clinical development

• Keep detailed, accurate, and up-to-date records of all experimental procedures and results  

• Present data at project team meetings and internal reviews with key stakeholders

• Lead, mentor, and develop scientists to drive scientific excellence and build a high-performing biology team

Qualifications & Skills

We’re looking for candidates who are curious, proactive, and collaborative, with a strong scientific foundation and hands-on technical expertise. Key qualifications include:

• Demonstrated success leading autoimmune or inflammatory disease programs
• Experience drafting/managing in vivo/ex-vivo pharmacology studies
• Experience in CRO management
• Demonstrated track record of independent critical thinking and scientific achievement in immunology as evidenced by contributions to INDs, patents, and/or publications
• Ability to thrive in a highly collaborative, fast-paced, team-oriented environment with colleagues from diverse disciplines is essential
• Outstanding oral and written communication skills, critical thinking and problem-solving skills are required

Education & Experience

• PhD in Immunology, Pharmacology, or related field preferred
• 8+ years of relevant industry experience (may include post doc)

• The expected base pay range for this position is $175,000 - $200,000 annually and will depend on several factors, including but not limited to, the candidate’s experience, skills and competencies. The pay range reflects several levels within the Scientific job family, and final title and compensation will be determined based on the candidate’s qualifications and relevant experience.

 

• This role is also eligible for annual performance bonuses, equity grants, and a comprehensive benefits package that includes medical, dental, vision, retirement plan, paid time off, and other employee programs.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.