Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal AI Engineer

Full-time

Velsera

Principal AI Engineer — Velsera AI Platform & Enablement · Reports to the CTO · Senior individual contributor About the role Velsera builds software and infrastructure for precision medicine — research platforms, clinical and diagnostic applications, and the systems that keep them running in regulated environments. We are adding AI capability across that portfolio and inside our own operations: governed model access, self-hosted and managed LLM serving, evaluation and audit, and integration into the products and business processes people already depend on. This is a deliberately broad role. You will be deployed where the highest-value AI work is at the time — a customer-facing product capability in one quarter, an internal enterprise workflow in the next, a strategic account or funded program after that. The mandate stays the same wherever you land: design and ship production AI systems that hold up under real compliance requirements, work across AWS, Azure, and GCP, and leave behind reusable patterns rather than one-off builds. You will set technical direction for what is expected to grow into an AI platform and enablement team. What you'll work on - Build a governed model access layer — self-hosted open-weight models, cloud-managed models (Bedrock, Vertex AI, Azure OpenAI), and customer- or partner-supplied models — designed to be consumed by more than one product or business function. - Integrate AI capabilities into product experiences and enterprise workflows across batch, interactive, and agentic patterns. - Establish the patterns everyone else reuses: evaluation, versioning, approvals, audit trails, cost control, guardrails, and safe rollout and rollback. - Partner with product, engineering, security, QARA/compliance, IT, and scientific and commercial teams to introduce AI-native architectures that people can actually adopt. - Move between assignments as business priorities shift, and make what you build in one part of the business usable in the next. What you'll deliver (first 6–12 months) - A production-ready, compliant AI/LLM serving and invocation layer that at least two products or business functions adopt — multi-tenant, auditable, and secure. - A model governance workflow (intake, evaluation, approval, versioning, deprecation) that satisfies both regulated customers and our own quality system. - Two or three AI capabilities shipped end to end in different parts of the business — for example a customer-facing product feature, an internal process automation, and assisted validation or compliance tooling. - Integration patterns that preserve reproducibility, traceability, and standards alignment wherever the work lands. - Operational readiness: monitoring, evaluation harnesses, incident playbooks, cost visibility, and measurable SLOs for key AI services.

- A defensible internal point of view on where we should build, buy, or not use AI at all — backed by what you shipped. How we build (and what we'll expect you to optimize for) You will make trade-offs in an environment that is multi-product, multi-cloud, standards-driven, and compliance-heavy. A few things matter a lot here: - Reusability over one-offs. Design the second and third use case into the first one. A solution that only works for one product or one team is a partial solution. - Standards and clean interfaces. Prefer open standards and well-defined boundaries over bespoke integrations. - Multi-cloud, multi-deployment reality. AWS, Azure, and GCP are all in play, alongside customer-managed and self-hosted environments. Avoid hard dependencies on a single provider's AI stack. - Security and auditability by default. Access control, logging, traceability, and data governance are part of the design, not add-ons. - Reproducibility. AI features have to fit into workflows and processes that need to be repeatable and explainable, sometimes years later. - Proportion.

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Principal AI Engineer in Remote vacancy
  • $103.2k - $128.9k

     ...Purpose Lead the design, development, and deployment of advanced AI and machine learning solutions supporting Honda’s automotive R&D...  ..., and digital twins—owning solutions end-to-end and mentoring engineers while partnering with CAE, CAD, manufacturing, and data platform... 
    Suggested
    Full time
    Temporary work
    Work experience placement
    Work at office
    Work from home
    Relocation package

    Honda Dev. and Mfg. of Am.,LLC

    Raymond, OH
    more than 2 months ago
  • $117k - $201.25k

     ...championing patients every step of the way.Learn more at the opportunityJohnson & Johnson Innovative Medicine is seeking a Principal Agentic Workflow & AI Engineer to help build the agentic layer of our Biologics Discovery data engine. This is an opportunity to be one of the... 
    Suggested
    Full time
    Temporary work
    Work at office
    Local area
    Remote work

    Johnson & Johnson

    Titusville, NJ
    4 days ago
  • $206.6k - $284.3k

     ...decisions today about how it will leverage AI over the next decade. Few have leaders...  ...its viability through hands-on engineering. This role requires both.We build the platform...  ...real healthcare outcomes for members.As a Principal AI Applied Engineer, you will define the... 
    Suggested
    Full time
    Temporary work
    Apprenticeship
    Work at office
    Remote work
    Relocation
    3 days per week

    Humana

    New York, NY
    3 days ago
  • $149.82k - $198.37k

     ...Are you ready to join a company with a strong purpose and a winning culture? Start your Voyage -Apply NowProfile Summary:The AI Principal Engineer (IC Director) role is responsible for leading the design and delivery of complex, production-grade AI systems with... 
    Suggested
    Full time
    Part time
    Work experience placement
    Local area
    Work from home
    Flexible hours

    Benefitfocus

    New York, NY
    16 hours ago
  •  ...for current or future sponsorship.The Cognitive and Generative AI Engineering team is responsible for developing and implementing AI-driven...  ...and scale AI adoption across Navy Federal Credit Union. The Principal AI Engineer is a senior, hands-on technical leader... 
    Suggested
    Internship
    Monday to Friday

    Navy Federal Credit Union

    Vienna, VA
    2 days ago
  • $149k

     ...Fairfax Financial Holdings. For more information about C&F, please visit our website: Job DescriptionCrum & Forster is seeking a Principal AI Engineer (GenAI & Agentic AI) to lead the AI solution architecture, and delivery of next-generation AI solutions that transform... 
    Work at office
    Remote work

    Crum & Forster

    Morristown, NJ
    16 hours ago
  • $217k - $325k

     .... As a Fortune 500 company and a leading AI platform for managing people, money, and...  ...that bring together product leaders, AI engineers, and full-stack builders to create intelligent...  ..., but brighter.About the RoleAs a Principal AI Engineer in Agent Factory, you will lead... 
    Full time
    Work at office
    Remote work
    Home office
    Flexible hours

    Workday

    Atlanta, GA
    1 day ago
  • $133.6k - $222.6k

     ...SummaryLPL Financial is seeking a highly technical and hands-on AI engineering leader to help design, build, and deploy next-generation AI...  ...log in or create an account to apply to this position. Principals only. EOE.Information on Interviews:LPL will only communicate... 
    Full time
    Work from home

    LPL Financial

    Austin, TX
    1 day ago
  • $130k - $196k

     ...health support, and an annual professional development stipend.To learn more about our offerings, click here. What You'll Do The Principal AI Engineer is a senior individual contributor who helps Strive turn AI into real operating leverage across the business. This role will... 
    Work at office
    Remote work
    Work from home
    Flexible hours

    Strive Health

    Denver, CO
    3 days ago
  • $180k - $200k

     ...our global team and see what makes Mitratech a truly exceptional place to work! Role Overview We are looking for a Principal AI Engineer to guide a distributed team of developers in building modern, scalable, and AI-integrated software solutions. As a... 
    Work at office
    Remote work

    Mitratech

    Remote
    6 hours ago
  • $207.2k - $259k

     ...visit transamerica.com.  Job Description SummaryAegon’s Core AI Team is scaling rapidly to meet growing demand for AI-driven...  ...Agentic AI capabilities. We are seeking an experienced Associate Principal AI Engineer to join Aegon’s Core AI team, evolve the organizations AI... 
    Full time
    Contract work
    Work at office
    Remote work
    Work from home
    Worldwide
    Work visa
    Relocation package
    3 days per week

    Transamerica

    Denver, CO
    1 day ago
  •  ...better way, and we create possibilities. Interested in joining us on our journey? We are looking for a highly motivated Principal Applied AI Engineer to join our digital innovation team and help revolutionize how we serve our B2B (Business-to-Business) and B2C (Business... 
    Full time
    Work at office
    Remote work
    Flexible hours

    GE Appliances

    Louisville, KY
    2 days ago
  •  ...MicrosoftOverviewAre you a customer-obsessed software engineer and technical architect who is passionate about applying AI to complex, real-world problems? The...  ...customer issues at Azure scale. We are seeking a Principal Applied AI Engineer to serve as a hands-on technical... 
    Ongoing contract
    Local area
    3 days per week

    Microsoft

    Redmond, WA
    1 day ago
  •  ...Agentic Ai & Mcp Specialist eSimplicity is a modern digital services company that partners with government agencies to improve...  ...veterans and service members to children, families, and seniors. Our engineers, designers, and strategists cut through complexity to create... 
    Remote work

    eSimplicity Inc

    United States
    16 hours ago
  • $180k - $200k

     ...company, Next Net , is investing heavily in AI. We're building a next-generation SaaS...  ..., distributed systems, and modern engineering practices to help businesses understand...  ...About the Position We're looking for a Principal AI Engineer to help build the future of... 
    Full time
    Casual work
    Work at office
    Local area
    Remote work
    Monday to Friday

    TheHOTH

    United States
    16 hours ago
  •  ...Location: US(NYC)- 3(WFO) Employment Type: Full Time (Overlapping EST) About the Role Hiring a Staff/Principal AI Engineer to lead enterprise-scale agentic AI implementations for Fortune 500 clients. This is a hands-on engineering role focused on designing and shipping... 
    Full time

    IMR SOFT LLC

    New York, NY
    3 days ago
  • $296.3k - $423.9k

     ...on a global scale.  We are looking for a Principal Technical Lead Manager (TLM) to lead the...  ...Trajectory Generation team within the Embodied AI organization. This role combines deep...  ...You will lead a high-performing team of engineers building ML-driven trajectory generation... 
    Full time
    Local area
    Remote work
    Work from home
    Relocation
    Relocation package
    Flexible hours

    General Motors

    Sunnyvale, CA
    4 days ago
  • $164.6k - $282.2k

     ...everyone. From advanced data analytics and AI to cybersecurity, we use innovative...  ...enterprise AI team. We are AI/ML scientists and engineers with deep expertise in AI/ML engineering...  ...AI/ML development platform.As a principal engineer within the enterprise AI Platforms... 
    Minimum wage
    Full time
    Contract work
    Work experience placement
    Work at office
    Local area
    Remote work

    UnitedHealth Group

    Eden Prairie, MN
    4 days ago
  • $132.8k - $250.8k

    The Principal Engineer - AIOps role at EPEO requires 12+ years of experience in AI/ML and software engineering with strong skills in Python, SQL, and cloud platforms. This position focuses on designing and deploying advanced AI/ML solutions for Security (Cyber & Identity... 
    Immediate start
    Visa sponsorship
    Flexible hours

    Ford

    Dearborn, MI
    3 days ago
  • $180k - $200k

     ...Principal Ai Engineer As a Principal AI Engineer at MRO, you will own the technical vision and implementation of AI capabilities that power our healthcare software products. You will design and build production AI systems — RAG pipelines, LLM integrations, human-in-... 
    Remote work

    Q-Centrix by MRO

    United States
    2 days ago
  • $166.64k - $250k

    Job DescriptionPosition SummaryVertex is seeking an AI Full-Stack Engineer to create the next generation of AI-powered applications and agents that deliver practical value across internal and user-facing experiences. This role will own solutions end to end—from user experience... 
    Full time
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    4 days ago
  • $164.6k - $282.2k

     ...work better for everyone. From advanced data analytics and AI to cybersecurity, we use innovative approaches to solve some...  ...start Caring. Connecting. Growing together.We are looking for a Principal AI/ML Engineer to lead the architecture, design, and end-to-end development... 
    Minimum wage
    Full time
    Work experience placement
    Work at office
    Local area
    Remote work

    UnitedHealth Group

    Plymouth, MN
    3 days ago
  • $187.5k - $229.1k

     ...authorizations to delivering comprehensive medication histories to facilitating messages between providers. Job Summary: The Principal AI Engineer is the most senior individual contributor and technical lead for Surescripts' AI solutions. The role owns the how, the... 
    Work at office
    Local area
    Immediate start
    Remote work
    Flexible hours

    Surescripts

    Minneapolis, MN
    16 hours ago
  • $5,000 per month

     ...love to connect with you. Join our team and build a career that you will be proud of. Explore Opportunities Today The Principal AI Engineer is a role where the domain is the entire business. The Principal AI Engineer will work directly with teams across Finance, Team... 
    Temporary work
    Local area
    Work from home
    Flexible hours
    3 days per week

    Stanley Martin

    Reston, VA
    5 days ago
  • $170k - $240k

    Seattle, Washington, United StatesProducts - Engineering /Fulltime /RemoteOver 50,000 customers globally trust our end...  ...the Extreme team.Position detailsTitle of position: Principal Machine Learning Engineer - Gen AI, Machine Learning, Graph MLPosition type: Full timeLocation... 
    Full time
    Local area
    Work from home
    Shift work

    Extreme Networks, Inc.

    Seattle, WA
    2 days ago
  • $190.2k - $360.5k

    The Opportunity We are looking for a Principal AI Systems Engineer with deep C++ expertise to help build the next generation of AI-enabled product and platform capabilities. This role sits at the intersection of large-scale systems engineering, applied AI, and production... 
    Full time
    Temporary work
    Local area
    Remote work
    Worldwide

    Adobe Systems

    San Francisco, CA
    16 hours ago
  • $120.5k - $231k

     ...we show up, everywhere & always. Want in? Join the #VTeamLife.What you’ll be doing...The Enterprise AI Control Plane team is looking for a hands-on architectural engineer to build the complex system connecting Verizon’s AI developer platforms (AWS Bedrock, Atlas AI)... 
    Full time
    Temporary work
    Part time
    Work experience placement
    Work at office
    Work from home
    Shift work
    3 days per week

    Verizon

    Irving, TX
    2 days ago
  • $114.6k - $252.1k

    Job Title: Principal AI/ML Engineer (Large Language Model)Job Category: ScienceTime Type: Full timeMinimum Clearance Required to Start: TS/SCI with PolygraphEmployee Type: RegularPercentage of Travel Required: Up to 10%Type of Travel: LocalAnticipated Posting End: 12/3... 
    Contract work
    Work experience placement
    Local area
    Remote work
    Flexible hours

    CACI International

    Philadelphia, PA
    16 hours ago
  • $175k - $200k

     ...Job Description Job Description Founded in 2012, H2O.ai is on a mission to democratize AI. As the world’s leading agentic...  ...information, visit  About This Opportunity  We are looking for a Principal AI Engineer who builds things that matter. You will design and ship end-... 
    Remote work
    Worldwide
    Flexible hours

    h2o.ai

    Dallas, TX
    24 days ago
  •  ...25%Profession: Software EngineeringDiscipline: Business ApplicationsCompany: MicrosoftOverviewAre you a customer-obsessed, AI-curious engineering leader who thrives in an inclusive, collaborative global team? The Azure Engineering Operations (EngOps) team's mission is... 
    Ongoing contract
    Local area
    3 days per week

    Microsoft

    Redmond, WA
    8 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal AI Engineer. Be the first to apply!