Director, Quantitative Science and Biometrics - Evinova

WHY JOIN US? Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor, and deep human insight, we design digital solutions that enable healthcare to work better for everyone.

Operating at the intersection of healthcare, technology, data, and analytics, we are helping unlock the full potential of digital health, transforming how clinical research is conducted, how care is delivered, and how patients experience healthcare. Our solutions are built to scale, driving efficiency, improving decision-making, and ultimately delivering better outcomes for patients worldwide. 

At Evinova, we are driven by a shared purpose to transform health through data and digital innovation. Our teams collaborate across disciplines to solve complex challenges, continuously learning and evolving in a fast-paced, high-impact environment. 

We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and team collaboration. To foster connection and collaboration, employees are expected to work from the office three days per week , creating opportunities for in-person teamwork, innovation, and meaningful connection.

About the Opportunity:

Are you ready to set new standards for how digital health measures capture what matters most to patients and clinicians? In this Director role, you will lead the strategy and execution of patient-centric measurement science—advancing clinical outcomes assessments and digital endpoints that shape decisions across oncology development. Your work will help define benefit–risk with clarity and speed, so more patients get effective treatments sooner.You will connect science-based rigor with human-centered design to build evidence that regulators, payers, sites, and patients trust. As part of a multidisciplinary team spanning product, clinical, data science, and regulatory, you will transform qualitative and quantitative insights into robust measures that improve trial design, enhance patient experience, and inform pivotal filings. The impact of your leadership will be visible in how we define, collect, and apply evidence to guide oncology decisions worldwide.

What You’ll Do:

As the Director, Quantitative Science and Biometrics, you will provide enterprise-level scientific leadership to make a positive impact on changing patients'

lives through the following:

• Strategic leadership: Own and drive the overarching strategy for quantitative evidence generation across therapeutic areas and the full product lifecycle - from clinical development through commercialization and market access

• Evidence framework development: Design and establish scalable frameworks and analytic approaches that address evidence gaps across multiple programs simultaneously

• Cross-functional influence: Lead and influence cross-functional stakeholders - including Clinical Development, Medical Affairs, Market Access, Commercial, and Regulatory teams - to refine endpoint strategy, comparator selection, and evidence positioning

• PRO and COA expertise: Serve as the enterprise authority on Patient-Reported Outcomes strategy, psychometric/clinimetric evaluation, measure selection, and clinical integration across pivotal and post-marketing studies

• Real-world evidence integration: Shape real-world evidence initiatives that support regulatory, payer, and market access strategies, leveraging population health data and digital health platforms

• Team leadership and mentorship: Provide scientific mentorship and oversight to Associate Directors and Scientists, building team capability and ensuring delivery excellence across concurrent workstreams

• Analytic delivery oversight: Oversee the conduct, interpretation, and communication of psychometric, clinimetric, and statistical analyses for the validation of novel endpoints leveraging COA data, sensor/wearable data, and hybrid sources in clinical trials

• Scientific communication: Lead the preparation, review, and publication of evidence, ensuring clinical validation findings are communicated effectively in scientific reports, conference presentations, peer-reviewed publications, and regulatory dossiers

• AI and automation strategy: Set direction for integrating AI-enabled analytics into quantitative workflows to enhance efficiency, scalability, and rigour of evidence generation at enterprise scale

• Digital product contribution: Lead the design and refinement of AI-powered decision-support tools within Evinova's digital health products, enabling external clients to optimise clinical trial execution and derive deeper insights from COA and sensor-based data

• Business development and thought leadership: Contribute to business development activities, proposal creation, and external thought leadership that advances Evinova's scientific credibility and market position

• Stakeholder engagement: Represent Evinova in external scientific forums, regulatory interactions, and industry partnerships

Essential Skills and Experience:

• Demonstrated strategic leadership in PRO, outcomes research, real-world evidence, or quantitative evidence generation across the product lifecycle (development through commercialization)

• Deep expertise in psychometric evaluation, COA validation, endpoint strategy, and measure selection for clinical trials and longitudinal studies

• Experience influencing cross-functional decision-making across Clinical Development, Medical Affairs, Market Access, and Commercial functions

• Programming and visualization proficiency using Python, R, SAS, SQL, or similar tools (hands-on working knowledge; able to lead, support, and interpret analyses)

• Experience with digital health platforms, ePRO systems, and/or sensor/wearable-derived data in clinical or population health contexts

• Proven ability to lead teams, mentor scientists, and manage a portfolio of concurrent activities in a fast-paced, matrixed environment

• Strong working knowledge of drug development and the regulatory landscape governing research with human subjects

• Exceptional communication and stakeholder engagement skills, with demonstrated ability to influence strategically and build relationships across organisational levels

• Experience in scientific communication, including publications, conference presentations, and regulatory submissions

• Creative, innovative, and solution-focused with the ability to navigate ambiguity, challenge the status quo, and drive accountability 

Education

• Doctoral degree (e.g., PhD, ScD, DrPH) in a relevant field such as Population Health Sciences, Statistics, Biostatistics, Psychology, Testing and Measurement, Epidemiology, Pharmaceutical Sciences, Neuroscience, or other quantitative-related fields, plus five or more years of relevant and progressive experience in pharmaceutical, digital health, consulting, or healthcare settings

OR:

• Master's degree in a related field, plus eight or more years of progressive practical experience

Desirable for the role:

• Oncology experience — familiarity with oncology clinical development, endpoints, or evidence strategy

• Experience in business development, proposal creation, or client-facing strategic engagement

• Background spanning multiple settings (e.g., pharmaceutical, digital health/health-tech, consulting, and/or healthcare

• provider environments)

• Experience with population health analytics, comparative effectiveness research, or health economic modelling

• Understanding of novel digital development frameworks and regulatory considerations for digital endpoints

• Track record of thought leadership — publications, conference presentations, or industry working group participation

• Experience scaling digital health or ePRO programs across large organisations

• Resilience and adaptability — ability to motivate and lead others through change in a dynamic environment

SO, WHAT’S NEXT?

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

Where can I find out more?

• Explore what we’re building:
• Stay connected and see our impact in action:

Apply today to bring smarter, faster clinical trials to life!

Evinova is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Evinova is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing  View email address on careers.astrazeneca.com .

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Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.